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Summary Expression Phenotypes Gene Literature (1) GO Terms (10) Nucleotides (183) Proteins (73) Interactants (22) Wiki
XB-GENEPAGE-998623

irf5     interferon regulatory factor 5

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: irf5 assayed (12 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (12 sources): abnormal T-helper 1 physiology, abnormal response to infection, decreased CD4-positive, alpha-beta memory T cell number, decreased circulating interleukin-12b level, decreased circulating interleukin-6 level, decreased circulating tumor necrosis factor level, decreased interferon-alpha secretion, decreased interleukin-6 secretion, decreased susceptibility to bacterial infection, decreased tumor necrosis factor secretion, [+]