| Monarch Ortholog Phenotypes
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Human (54 sources):
Abnormality of skin pigmentation,
Anteverted nares,
Bifid uvula,
Brittle hair,
Capillary hemangioma,
Carious teeth,
Cleft palate,
Coarse hair,
Cryptorchidism,
Decreased skull ossification,
Delayed closure of the anterior fontanelle,
Delayed eruption of teeth,
Delayed speech and language development,
Esotropia,
Forehead hyperpigmentation,
Frontal bossing,
Gastroesophageal reflux,
High iliac wing,
High palate,
Hyperpigmentation of the skin,
Hypertelorism,
Hypoplasia of teeth,
Hypoplasia of the maxilla,
Large fontanelles,
Long philtrum,
Macrocephaly,
Malar flattening,
Microdontia,
Midface retrusion,
Narrow chest,
Narrow iliac wing,
Optic atrophy,
Osteopenia,
Pes planus,
Posterior Y-sutural cataract,
Posterior wedging of vertebral bodies,
Premature loss of teeth,
Prominent nasal bridge,
Prominent supraorbital ridges,
Punctate cataract,
Scoliosis,
Short stature,
Skeletal dysplasia,
Smooth philtrum,
Sparse hair,
Sutural cataract,
Thin upper lip vermilion,
Thin vermilion border,
Wide anterior fontanel,
Wide mouth,
Wide nasal bridge,
Wide nose,
obsolete Joint hyperflexibility,
obsolete Joint laxity
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Mouse (14 sources):
abnormal amnion morphology,
abnormal cartilage development,
abnormal collagen level,
abnormal extraembryonic tissue physiology,
abnormal telencephalon development,
abnormal visceral yolk sac morphology,
collapsed brain ventricles,
decreased embryo size,
decreased embryonic neuroepithelial cell proliferation,
embryonic lethality during organogenesis, complete penetrance,
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.