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GEO Series: GSE116819

Title: Transcriptome analysis of wild type and RAR deficient frog faces during development

Summary

We utilized RNASeq to investigate the changes in mRNA expression when retinoic acid signaling is inhibited by treatment with an RAR inhibitor, BMS453.


Contributors: Stacey Wahl, Stephen Turner, Amanda Dickinson

Experiment Type: Embryos were treated with RAR inhibtior during the latter stage of facial development, 35-66 hours post fertilzation, facial region was dissection and global changes in gene expression were assessed. Further analyses to determine funcitonal networks that were affected was performed.

Experiment Reagents: BMS 453.

Phenotypes:
Xla Wt + BMS453 + intercanthal region NF40 (RNA-Seq (RNA))

Article: XB-ART-55440, PubMed

Source: NCBI GEO, Xenbase Download

Samples: (DEG = Differentially Expressed Genes; GSM = GEO Sample Number)
Sample View GSMs Assay Type
intercanthal region - NF40 GSM3262255  GSM3262256  GSM3262257  RNA-Seq
Background: Xla.Outbred
Conditions:
Tissue Assay Stages ChIP Antibody
intercanthal region NF stage 40  
   intercanthal region + BMS453 - NF40 DEG GSM3262258  GSM3262259  GSM3262260  RNA-Seq
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
chemical BMS 453 NF stage 35 and 36 embryo
Conditions:
Tissue Assay Stages ChIP Antibody
intercanthal region NF stage 40  
Select All DEG      Select All 
Xtr   
Xla 

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