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XB-ART-19995
J Biol Chem 1995 Mar 03;2709:4197-200.
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Methylation at CpG sequences does not influence histone H1 binding to a nucleosome including a Xenopus borealis 5 S rRNA gene.

Nightingale K , Wolffe AP .


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We demonstrate that methylation of the 12 dinucleotide CpGs within a GC-rich DNA fragment containing a Xenopus borealis 5 S rRNA gene does not influence histone H1 binding to naked or nucleosomal 5 S DNA. Thus a simple mechanism in which histone H1 selectively associates with nucleosomes containing methylated CpG cannot explain the repressive effects of methylation on gene activity.

???displayArticle.pubmedLink??? 7876175
???displayArticle.link??? J Biol Chem