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XB-ART-220
Curr Biol 2006 Jun 20;1612:R466-8. doi: 10.1016/j.cub.2006.05.032.
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Cell biology: Ran, mitosis and the cancer connection.

Sanderson HS , Clarke PR .


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The small GTPase Ran has been shown to regulate HURP, a protein that interacts with several mitotic spindle assembly factors. This discovery sheds new light on the role of Ran in the fidelity of mitosis and in cancer.

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Species referenced: Xenopus
Genes referenced: dlgap5 ran

References [+] :
Koffa, HURP is part of a Ran-dependent complex involved in spindle formation. 2006, Pubmed, Xenbase