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XB-ART-32577
Biochim Biophys Acta 1976 Jan 21;4192:342-8.
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Nature of progesterone action on amino acid uptake by isolated full-grown oocyte of Xenopus laevis.

Bellé R , Marot J , Ozon R .


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L-leucine uptake into full-grown oocytes of Xenopus laevis is a saturable process which is Na+ dependent and presumably coupled to Na+ gradient. Our results indicate that progesterone (10(-6) M) Blocks abruptly, around the germinal vesicle breakdown, the saturable transport of L-leucine. p-Chloromercuribenzoate (10(-4) M) induces maturation and after a short lag of time strongly inhibits L-leucine uptake. Cycloheximide prevents progesterone-induced maturation and permeability changes.

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