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XB-ART-3741
Neuron 2004 Apr 08;421:3-5. doi: 10.1016/s0896-6273(04)00194-1.
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Lipid rafts as organizing platforms for cell chemotaxis and axon guidance.

Ibáñez CF .


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Lipid rafts are thought to serve as plasma membrane platforms for localized trafficking and signaling. Recent findings reported by Guirland et al. in this issue of Neuron and by Gómez-Moutón in a recent issue of JCB support a direct role of lipid microdomains in organizing spatial signaling during axon guidance and cell chemotaxis by concentrating the gradient-sensing machinery at the leading edge.

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Species referenced: Xenopus
Genes referenced: tbx2

References :
Guirland, Lipid rafts mediate chemotropic guidance of nerve growth cones. 2004, Pubmed, Xenbase