Brosnan RJ , Fukushima FB , Pham TL .

R01 GM092821 NIGMS NIH HHS

Antognini, Exaggerated anesthetic requirements in the preferentially anesthetized brain. 1993, Pubmed

Antognini, Exaggerated anesthetic requirements in the preferentially anesthetized brain. 1993, Pubmed
Bazil, Sympathoexcitation from the rostral ventrolateral medulla is mediated by spinal NMDA receptors. 1993, Pubmed
Brosnan, Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. 2014, Pubmed , Xenbase
Brosnan, Inhaled anesthetics in horses. 2013, Pubmed
Brosnan, Increased NMDA receptor inhibition at an increased Sevoflurane MAC. 2012, Pubmed
Brosnan, Chirality in anesthesia II: stereoselective modulation of ion channel function by secondary alcohol enantiomers. 2006, Pubmed , Xenbase
Brosnan, Does anesthetic additivity imply a similar molecular mechanism of anesthetic action at N-methyl-D-aspartate receptors? 2011, Pubmed , Xenbase
Brosnan, Carbon dioxide negatively modulates N-methyl-D-aspartate receptors. 2008, Pubmed , Xenbase
Brosnan, GABA(A) receptor antagonism increases NMDA receptor inhibition by isoflurane at a minimum alveolar concentration. 2011, Pubmed
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Franks, Molecular targets underlying general anaesthesia. 2006, Pubmed
Fung, Involvement of pontile NMDA receptors in inspiratory termination in rat. 1994, Pubmed
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Hara, Nonhalogenated alkanes cyclopropane and butane affect neurotransmitter-gated ion channel and G-protein-coupled receptors: differential actions on GABAA and glycine receptors. 2002, Pubmed , Xenbase
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Hendrickx, Is synergy the rule? A review of anesthetic interactions producing hypnosis and immobility. 2008, Pubmed
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Lin, General anesthetics potentiate gamma-aminobutyric acid actions on gamma-aminobutyric acidA receptors expressed by Xenopus oocytes: lack of involvement of intracellular calcium. 1992, Pubmed , Xenbase
Liu, Effect of n-alkane kinetics in rats on potency estimations and the Meyer-Overton hypothesis. 1994, Pubmed
Liu, Is there a cutoff in anesthetic potency for the normal alkanes? 1993, Pubmed
McKenzie, Actions of general anaesthetics on a neuronal nicotinic acetylcholine receptor in isolated identified neurones of Lymnaea stagnalis. 1995, Pubmed
Mihic, Potentiation of gamma-aminobutyric acid type A receptor-mediated chloride currents by novel halogenated compounds correlates with their abilities to induce general anesthesia. 1994, Pubmed , Xenbase
Ogata, Effects of anesthetics on mutant N-methyl-D-aspartate receptors expressed in Xenopus oocytes. 2006, Pubmed , Xenbase
Ohtake, NMDA receptors mediate peripheral chemoreceptor afferent input in the conscious rat. 1998, Pubmed
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Petrenko, Reduced immobilizing properties of isoflurane and nitrous oxide in mutant mice lacking the N-methyl-D-aspartate receptor GluR(epsilon)1 subunit are caused by the secondary effects of gene knockout. 2010, Pubmed
Raines, Nonhalogenated alkane anesthetics fail to potentiate agonist actions on two ligand-gated ion channels. 2001, Pubmed
Raines, Modulation of GABA(A) receptor function by nonhalogenated alkane anesthetics: the effects on agonist enhancement, direct activation, and inhibition. 2003, Pubmed , Xenbase
Raines, Nonhalogenated anesthetic alkanes and perhalogenated nonimmobilizing alkanes inhibit alpha(4)beta(2) neuronal nicotinic acetylcholine receptors. 2002, Pubmed , Xenbase
Rau, Gamma-aminobutyric acid type A receptor β3 subunit forebrain-specific knockout mice are resistant to the amnestic effect of isoflurane. 2011, Pubmed
Shafer, Additivity versus synergy: a theoretical analysis of implications for anesthetic mechanisms. 2008, Pubmed
Soares, Solubility of haloether anesthetics in human and animal blood. 2012, Pubmed
Solt, Differential modulation of human N-methyl-D-aspartate receptors by structurally diverse general anesthetics. 2006, Pubmed , Xenbase
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Sonner, Inhaled anesthetics and immobility: mechanisms, mysteries, and minimum alveolar anesthetic concentration. 2003, Pubmed
Stabernack, Spinal N-methyl-d-aspartate receptors may contribute to the immobilizing action of isoflurane. 2003, Pubmed
Taheri, Anesthesia by n-alkanes not consistent with the Meyer-Overton hypothesis: determinations of the solubilities of alkanes in saline and various lipids. 1993, Pubmed
Williams, A note on robust variance estimation for cluster-correlated data. 2000, Pubmed
Won, Hypothermia decreases ethanol MAC in rats. 2006, Pubmed
Yamakura, Effects of gaseous anesthetics nitrous oxide and xenon on ligand-gated ion channels. Comparison with isoflurane and ethanol. 2000, Pubmed , Xenbase
Yang, Anesthetic properties of the ketone bodies beta-hydroxybutyric acid and acetone. 2007, Pubmed , Xenbase
Yang, The plasticizer di(2-ethylhexyl) phthalate modulates gamma-aminobutyric acid type A and glycine receptor function. 2007, Pubmed , Xenbase
Zhang, Both cerebral GABA(A) receptors and spinal GABA(A) receptors modulate the capacity of isoflurane to produce immobility. 2001, Pubmed