Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-4340
Curr Opin Cell Biol 2003 Dec 01;156:672-83. doi: 10.1016/j.ceb.2003.10.013.
Show Gene links Show Anatomy links

Mitotic mechanics: the auroras come into view.

Andrews PD , Knatko E , Moore WJ , Swedlow JR .


???displayArticle.abstract???
Aurora kinases have recently taken centre stage in the regulation of key cell cycle processes. Aurora A is emerging as a critical regulator of centrosome and spindle function. Aurora B mediates chromosome segregation by ensuring proper biorientation of sister chromatids, possibly through the regulation of microtubule dynamics. This enzyme also functions in cytokinesis apparently by interacting with a critical GTPase and a kinesin-like protein. Recent work on both kinases has revealed functional links between Aurora kinase activity and the mechanics of cell division.

???displayArticle.pubmedLink??? 14644191
???displayArticle.link??? Curr Opin Cell Biol