Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xtr.foxl2em2NXR | X. tropicalis | foxl2 | 2nd CRISPR knockout of foxl2 (forkhead box L2). Germline transmission confirmed. Mosaic founders and... | |
| Xtr.foxp3em2NXR | X. tropicalis | foxp3 | CRISPR knockout of foxp3 (forkhead box P3). Germ line transmission confirmed. Animals carry a 17 bp ... | |
| Xtr.fermt2tm-/- Huzha | X. tropicalis | fermt2 | This is a CRISPR generated mutant giving rise to a 10bp deletion in the fermt2/kindlin2 gene. | |
| Xtr.apcMRCΔ1/+Vlemx | X. tropicalis | apc | F0 apc mosaics generated by apc TALENs injection, were outcrossed with WT X. tropicalis, and offspri... | |
| Xtr.Tg(mlc2:dnfosl1-eGFP)Qi | X. tropicalis | fosl1 | Fosl1 protein was mutated and truncated to generate 3 mutant polypeptides which then cloned into pc... | |
| Xtr.mtnr1aemNXR | X. tropicalis | mtnr1a | CRISPR knock out of mtnr1a (melatonin receptor 1A ) in X. tropicalis. germ line transmission confirm... | NXR |
| Xtr.six1em2NXR | X. tropicalis | six1 | CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... | NXR |
| Xtr.zmym4emNXR | X. tropicalis | zmym4 | CRISPR KO of zmym4 (zinc finger MYM-type containing 4) in X. tropicalis. Germline transmission confi... | NXR |
| Xtr.zeb2emNXR | X. tropicalis | zeb2 | CRISPR KO of zeb2 (zinc finger E-box binding homeobox 2), a gene associated with Mowat-Wilson syndro... | NXR |
| Xtr.ywhazemNXR | X. tropicalis | ywhaz | CRISPR KO of ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). Ge... | NXR |
| Xtr.xbp1emNXR | X. tropicalis | xbp1 | CRISPR KO of xbp1 ( X-box binding protein 1 ) a gene assocaited with Major Affected Disorder in huma... | NXR |
| Xla.baz1bemNXR | X. laevis | baz1b.L | TALENs knockout of baz1b (bromodomain adjacent to zinc finger domain 1B ) aka 'wstf', a gene associa... | |
| Xla.wnt11bemNXR | X. laevis | wnt11b.L | CRISPR knockout of wnt11b in X laevis. Germline transmission confirmed. F2 animals carry a 13bp de... | NXR |
| Xtr.wnt11bemNXR | X. tropicalis | wnt11b | X. tropicalis CRISPR knockout of wnt11b (wingless-type MMTV integration site family, member 11B ), ... | NXR |
| Xtr.wbp11emNXR | X. tropicalis | wbp11 | CRISPR knockout of wbp11 (WW domain binding protein 11). Germline transmission confirmed, F2s growin... | NXR |
| Xtr.vwa2emNXR | X. tropicalis | vwa2 | CRISPR knock out of vwa2 (von Willebrand factor A domain containing 2 ). Germ line transmission conf... | |
| Xtr.vangl2emNXR | X. tropicalis | vangl2 | CRISPR knockout of vangl2 (VANGL planar cell polarity protein 2 ), a gene associated with neural tub... | NXR |
| Xtr.tspan8em3Horb | X. tropicalis | tspan8 | CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 3rd of 3 tspan lines at... | NXR |
| Xtr.tspan8em2Horb | X. tropicalis | tspan8 | CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 2nd of 3 tspan lines at... | NXR |
| Xla.trilemNXR | X. laevis | tril.L tril.S | CRISPR knockout of tril (LR4 interactor with leucine-rich repeats). Co-injected for both L and S. Ge... | NXR |
| Xla.thrbem3NXR | X. laevis | thrb.L | Double CRISPR mutant line of thrb (thyroid hormone receptor, beta ) with animals carrying a 8bp dele... | |
| Xla.thrbem2NXR | X. laevis | thrb.S | CRISPR knockout of thrb.S thyroid hormone receptor, beta S homolog). germline transmission confirmed... | |
| Xla.thrbem1NXR | X. laevis | thrb.L | CRISPR knockout of thrb.L thyroid hormone receptor, beta L homolog). germline transmission confirmed... | |
| Xtr.tdrd1emNXR | X. tropicalis | tdrd1 | CRISPR knockout of tdrd1 (tudor domain containing 1). Germline transmission not yet confirmed. growi... | NXR |
| Xtr.srd5a3emNXR | X. tropicalis | srd5a3 | CRISPR knockout of srd5a3 (steroid 5 alpha-reductase 3), Germ line transmission confirmed. F1 growin... | |
| Xtr.srd5a2emNXR | X. tropicalis | srd5a2 | CRISPR knockout of srd5a2 (steroid 5 alpha-reductase 2), Confirmed germ line transmission. animals c... | |
| Xla.sobpemNXR | X. tropicalis | sobp | CRISPR knockout of sobp (sine oculis binding protein homolog ), a gene associated with MRAMS, an in... | |
| Xtr.snai2emNXR | X. tropicalis | snai2 | CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... | NXR |
| Xtr.snai1emNXR | X. tropicalis | snai1 | CRISPR knockout of snai1 (snail family zinc finger 1) in X. tropicalis. germline transmission confir... | NXR |
| Xtr.six1em1NXR | X. tropicalis | six1 | CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... | NXR |
| Xtr.sf3b4emNXR | X. tropicalis | sf3b4 | CRISPR knockout of sf3b4 (splicing factor 3b subunit 4) in X tropicalis. sf3b4 is a gene associated ... | NXR |
| Xla.slc45a2em2NXR | X. laevis | slc45a2.L | CRISPR knockout of slc45a2 (solute carrier family 45 member 2 ). Screened for germline transmission.... | |
| Xtr.foxn1emHuarc | X. tropicalis | foxn1 | An athymic line with TALEN-mediated targeted mutation in foxn1 gene, made by the Yaoita Lab. Absence... | NBRP |
| Xtr.rxraemNXR | X. tropicalis | rxra | CRISPR knockout of rxra (retinoid X receptor alpha ). Germ line transmission confirmed. Animals carr... | NXR |
| Xtr.runx1em3NXR | X. tropicalis | runx1 | CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani... | NXR |
| Xtr.runx1em2NXR | X. tropicalis | runx1 | CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani... | NXR |
| Xtr.rspo2emNXR | X. tropicalis | rspo2 | CRISPR knockout of rspo2 (R-spondin 2 ). Germ line transmission confirmed. Contact NXR for more deta... | NXR |
| Xtr.ror2emNXR | X. tropicalis | ror2 | CRISPR knockout of ror2 (receptor tyrosine kinase like orphan receptor 2). Germ line transmission no... | NXR |
| Xtr.ripply3emNXR | X. tropicalis | ripply3 | CRISPR KO of ripply3 (ripply transcriptional repressor 3). Germ line transmission confirmed. Animal... | NXR |
| Xtr.rfx6emNXR | X. tropicalis | rfx6 | CRISPR KO of rfx6 (regulatory factor X6) in X. tropicalis. Germ line transmission not yet confirm... | NXR |
| Xtr.rflciiemNXR | X. tropicalis | rflcii | CRISPR KO of rflcii ( relaxin family locus C type II ) in X tropicalis. Germ line transmission not y... | NXR |
| Xla.prkdcem1NXR | X. laevis | prkdc.L | CRISPR KO of prkdc (protein kinase, DNA-activated, catalytic subunit ). Germ line transmission confi... | NXR |
| Xtr.pqbp1emNXR | X. tropicalis | pqbp1 | CRISPR KO of pqbp1 (polyglutamine binding protein 1) in X tropicalis. Germ line transmission confirm... | NXR |
| Xtr.pou4f1emNXR | X. tropicalis | pou4f1 | CRISPR knockout of pou4f1 (POU class 4 homeobox 1) in X. tropicalis. germ line transmission confirme... | NXR |
| Xtr.pnhdemNXR | X. tropicalis | pnhd | CRISPR knockout of pnhd (pinhead) in X tropicalis. Germ line transmission confirmed. Mutation is a ... | NXR |
| Xtr.plekhg5emNXR | X. tropicalis | plekhg5 | CRISPR knockout of plekhg5 (pleckstrin homology and RhoGEF domain containing G5 ) Germ line transmis... | NXR |
| Xtr.pigpemNXR | X. tropicalis | pigp | CRISPR knockout of pigp (phosphatidylinositol glycan anchor biosynthesis class P )in X tropicalis. G... | |
| Xtr.olig3emNXR | X. tropicalis | olig3 | CRISPR knockout of olig3 (oligodendrocyte transcription factor 3) in X. tropicalis. Current mosaic ... | |
| Xtr.nr2f2emNXR | X. tropicalis | nr2f2 | CRISPR knockout fo nr2f2 (nuclear receptor subfamily 2 group F member 2 ). Germ line transmission co... | |
| Xtr.naa20emNXR | X. tropicalis | naa20 | CRISPR knockout fo naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit ). Germ line transmi... |
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