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R-Spondin 2 governs Xenopus left- right body axis formation by establishing an FGF signaling gradient. , Lee H , Lee H ., Nat Commun. February 2, 2024; 15 (1): 1003.
Maternal Wnt11b regulates cortical rotation during Xenopus axis formation: analysis of maternal-effect wnt11b mutants. , Houston DW ., Development. September 1, 2022; 149 (17):
The role of Xenopus developmental biology in unraveling Wnt signalling and antero- posterior axis formation. , Niehrs C ., Dev Biol. February 1, 2022; 482 1-6.
R-spondins are BMP receptor antagonists in Xenopus early embryonic development. , Lee H , Lee H ., Nat Commun. November 4, 2020; 11 (1): 5570.
TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis. , Chen M., Elife. September 14, 2020; 9
The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer. , Chang LS., Elife. January 14, 2020; 9
Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis. , Ding Y ., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.
Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. , Kirsch N., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.
A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway. , Salašová A., Mol Neurodegener. July 11, 2017; 12 (1): 54.
The phosphatase Pgam5 antagonizes Wnt/ β-Catenin signaling in embryonic anterior- posterior axis patterning. , Rauschenberger V., Development. June 15, 2017; 144 (12): 2234-2247.
CD44 functions in Wnt signaling by regulating LRP6 localization and activation. , Schmitt M., Cell Death Differ. April 1, 2015; 22 (4): 677-89.
Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation. , Zhang X., Dev Cell. March 23, 2015; 32 (6): 719-30.
A Molecular atlas of Xenopus respiratory system development. , Rankin SA , Rankin SA ., Dev Dyn. January 1, 2015; 244 (1): 69-85.
PTK7 modulates Wnt signaling activity via LRP6. , Bin-Nun N., Development. January 1, 2014; 141 (2): 410-21.
RAB8B is required for activity and caveolar endocytosis of LRP6. , Demir K., Cell Rep. September 26, 2013; 4 (6): 1224-34.
The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling. , Wang F., Dev Biol. July 1, 2013; 379 (1): 16-27.
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation. , Zhang X., Cell. June 22, 2012; 149 (7): 1565-77.
Maternal xNorrin, a canonical Wnt signaling agonist and TGF-β antagonist, controls early neuroectoderm specification in Xenopus. , Xu S., PLoS Biol. January 1, 2012; 10 (3): e1001286.
Waif1/5T4 inhibits Wnt/ β-catenin signaling and activates noncanonical Wnt pathways by modifying LRP6 subcellular localization. , Kagermeier-Schenk B., Dev Cell. December 13, 2011; 21 (6): 1129-43.
Transdifferentiation from cornea to lens in Xenopus laevis depends on BMP signalling and involves upregulation of Wnt signalling. , Day RC., BMC Dev Biol. January 26, 2011; 11 54.
Cell cycle control of wnt receptor activation. , Davidson G., Dev Cell. December 1, 2009; 17 (6): 788-99.
Extracellular regulation of developmental cell signaling by XtSulf1. , Freeman SD., Dev Biol. August 15, 2008; 320 (2): 436-45.
The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition. , Cruciat CM., J Biol Chem. May 5, 2006; 281 (18): 12986-93.
Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF. , Yamamoto A., Cell. January 28, 2005; 120 (2): 223-35.
Connective- tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex. , Mercurio S., Development. May 1, 2004; 131 (9): 2137-47.
Wise, a context-dependent activator and inhibitor of Wnt signalling. , Itasaki N., Development. September 1, 2003; 130 (18): 4295-305.
Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning. , Davidson G., Development. December 1, 2002; 129 (24): 5587-96.
A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling. , Holmen SL., J Biol Chem. September 20, 2002; 277 (38): 34727-35.
Cloning and expression of Xenopus Lrp5 and Lrp6 genes. , Houston DW ., Mech Dev. September 1, 2002; 117 (1-2): 337-42.