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Unexpected Effect of IL-1β on the Function of GABAA Receptors in Pediatric Focal Cortical Dysplasia. , Alfano V., Brain Sci. June 19, 2022; 12 (6):
SLC12A2 variants cause a neurodevelopmental disorder or cochleovestibular defect. , McNeill A., Brain. August 1, 2020; 143 (8): 2380-2387.
Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti-seizure efficacy. , Brandt C., Neuropharmacology. December 1, 2018; 143 186-204.
A novel GABAergic dysfunction in human Dravet syndrome. , Ruffolo G., Epilepsia. November 1, 2018; 59 (11): 2106-2117.
Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium-potassium-chloride-cotransporter human variants hNKCC1A and hNKCC1B. , Hampel P., Sci Rep. June 29, 2018; 8 (1): 9877.
Cotransporter-mediated water transport underlying cerebrospinal fluid formation. , Steffensen AB., Nat Commun. June 4, 2018; 9 (1): 2167.
Functional aspects of early brain development are preserved in tuberous sclerosis complex (TSC) epileptogenic lesions. , Ruffolo G., Neurobiol Dis. November 1, 2016; 95 93-101.
Endocannabinoid signaling enhances visual responses through modulation of intracellular chloride levels in retinal ganglion cells. , Miraucourt LS., Elife. August 8, 2016; 5
The search for NKCC1-selective drugs for the treatment of epilepsy: Structure-function relationship of bumetanide and various bumetanide derivatives in inhibiting the human cation-chloride cotransporter NKCC1A. , Lykke K., Epilepsy Behav. June 1, 2016; 59 42-9.
An in vivo screen to identify candidate neurogenic genes in the developing Xenopus visual system. , Bestman JE ., Dev Biol. December 15, 2015; 408 (2): 269-91.
Contributions of the Na⁺/K⁺-ATPase, NKCC1, and Kir4.1 to hippocampal K⁺ clearance and volume responses. , Larsen BR., Glia. April 1, 2014; 62 (4): 608-22.
Similar effects of all WNK3 variants on SLC12 cotransporters. , Cruz-Rangel S., Am J Physiol Cell Physiol. September 1, 2011; 301 (3): C601-8.
Anomalous levels of Cl- transporters cause a decrease of GABAergic inhibition in human peritumoral epileptic cortex. , Conti L., Epilepsia. September 1, 2011; 52 (9): 1635-44.
WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters. , Rinehart J., J Biol Chem. August 26, 2011; 286 (34): 30171-80.
Anomalous levels of Cl- transporters in the hippocampal subiculum from temporal lobe epilepsy patients make GABA excitatory. , Palma E ., Proc Natl Acad Sci U S A. May 30, 2006; 103 (22): 8465-8.
WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability. , Kahle KT., Proc Natl Acad Sci U S A. November 15, 2005; 102 (46): 16783-8.
WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia. , Kahle KT., Proc Natl Acad Sci U S A. February 17, 2004; 101 (7): 2064-9.
Molecular mechanisms of Cl- transport by the renal Na(+)-K(+)-Cl- cotransporter. Identification of an intracellular locus that may form part of a high affinity Cl(-)-binding site. , Gagnon E., J Biol Chem. February 13, 2004; 279 (7): 5648-54.
Cloning and functional characterization of a cation-Cl- cotransporter-interacting protein. , Caron L., J Biol Chem. October 13, 2000; 275 (41): 32027-36.