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Summary Anatomy Item Literature (7381) Expression Attributions Wiki

Papers associated with brain (and gabarap)

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GABAA Receptors Expressed in Oligodendrocytes Cultured from the Neonatal Rat Contain α3 and γ1 Subunits and Present Differential Functional and Pharmacological Properties., Ordaz RP., Mol Pharmacol. January 1, 2021; 99 (2): 133-146.

In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders., Grupe M., Eur J Pharmacol. November 15, 2020; 887 173440.

Erythropoietin Increases GABAA Currents in Human Cortex from TLE Patients., Roseti C., Neuroscience. January 1, 2020; 439 153-162.

Cloning and Expression of Cockroach α7 Nicotinic Acetylcholine Receptor Subunit., Cartereau A., Front Physiol. January 1, 2020; 11 418.            

The desensitization pathway of GABAA receptors, one subunit at a time., Gielen M., Nat Commun. January 1, 2020; 11 (1): 5369.                

Differential Coassembly of α1-GABAARs Associated with Epileptic Encephalopathy., Hannan S., J Neurosci. January 1, 2020; 40 (29): 5518-5530.

Multiple actions of fenamates and other nonsteroidal anti-inflammatory drugs on GABAA receptors., Mansikkamäki S., Eur J Pharmacol. June 15, 2019; 853 247-255.

Design and Synthesis of Novel Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors with the Ability To Rescue Auditory Gating Deficit in Mice., Li Y., J Med Chem. January 1, 2019; 62 (1): 159-173.

Ketone body modulation of ligand-gated ion channels., Pflanz NC., Neuropharmacology. January 1, 2019; 148 21-30.

Involvement of the GABAA receptor α subunit in the mode of action of etifoxine., Mattei C., Pharmacol Res. January 1, 2019; 145 104250.

Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions., Anderson LL., Epilepsia. January 1, 2019; 60 (11): 2224-2234.                    

Steady-state activation of the high-affinity isoform of the α4β2δ GABAA receptor., Pierce SR., Sci Rep. January 1, 2019; 9 (1): 15997.

Direct intertectal inputs are an integral component of the bilateral sensorimotor circuit for behavior in Xenopus tadpoles., Gambrill AC., J Neurophysiol. January 1, 2018; 119 (5): 1947-1961.

A novel action of lacosamide on GABAA currents sets the ground for a synergic interaction with levetiracetam in treatment of epilepsy., Ruffolo G., Neurobiol Dis. January 1, 2018; 115 59-68.

Suramin is a novel competitive antagonist selective to α1β2γ2 GABAA over ρ1 GABAC receptors., Luo H., Neuropharmacology. January 1, 2018; 141 148-157.

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission., Knoflach F., J Vis Exp. January 1, 2018; (138):                                 

A novel GABAergic dysfunction in human Dravet syndrome., Ruffolo G., Epilepsia. January 1, 2018; 59 (11): 2106-2117.

Structural basis of neurosteroid anesthetic action on GABAA receptors., Chen Q., Nat Commun. January 1, 2018; 9 (1): 3972.              

Mutation of the inhibitory ethanol site in GABAA ρ1 receptors promotes tolerance to ethanol-induced motor incoordination., Blednov YA., Neuropharmacology. September 1, 2017; 123 201-209.

HPLC-Based Activity Profiling for GABAA Receptor Modulators in Extracts: Validation of an Approach Utilizing a Larval Zebrafish Locomotor Assay., Moradi-Afrapoli F., J Nat Prod. January 1, 2017; 80 (5): 1548-1557.

Assembly rules for GABAA receptor complexes in the brain., Martenson JS., Elife. January 1, 2017; 6             

Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes., Borghese CM., Sci Rep. January 1, 2017; 7 (1): 6230.        

Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the α5 subunit., Stamenić TT., Eur J Pharmacol. November 15, 2016; 791 433-443.

Functional aspects of early brain development are preserved in tuberous sclerosis complex (TSC) epileptogenic lesions., Ruffolo G., Neurobiol Dis. November 1, 2016; 95 93-101.

Pharmacological induction of skin pigmentation unveils the neuroendocrine circuit regulated by light., Bertolesi GE., Pigment Cell Melanoma Res. March 1, 2016; 29 (2): 186-98.

A Cysteine Substitution Probes β3H267 Interactions with Propofol and Other Potent Anesthetics in α1β3γ2L γ-Aminobutyric Acid Type A Receptors., Stern AT., Anesthesiology. January 1, 2016; 124 (1): 89-100.

Functional sites involved in modulation of the GABAA receptor channel by the intravenous anesthetics propofol, etomidate and pentobarbital., Maldifassi MC., Neuropharmacology. January 1, 2016; 105 207-214.

Novel positive allosteric modulators of GABAA receptors with anesthetic activity., Maldifassi MC., Sci Rep. January 1, 2016; 6 25943.                  

Zolpidem is a potent stoichiometry-selective modulator of α1β3 GABAA receptors: evidence of a novel benzodiazepine site in the α1-α1 interface., Che Has AT., Sci Rep. January 1, 2016; 6 28674.          

Fragile X mental retardation protein knockdown in the developing Xenopus tadpole optic tectum results in enhanced feedforward inhibition and behavioral deficits., Truszkowski TL., Neural Dev. January 1, 2016; 11 (1): 14.          

Molecular mode of action of CGS 9895 at α1 β2 γ2 GABAA receptors., Maldifassi MC., J Neurochem. January 1, 2016; 138 (5): 722-30.

A pharmacological assessment of agonists and modulators at α4β2γ2 and α4β2δ GABAA receptors: The challenge in comparing apples with oranges., Ahring PK., Pharmacol Res. January 1, 2016; 111 563-576.

Cannabis in epilepsy: From clinical practice to basic research focusing on the possible role of cannabidivarin., Morano A., Epilepsia Open. January 1, 2016; 1 (3-4): 145-151.    

Structure-dependent inhibition of the human α1β2γ2 GABAA receptor by piperazine derivatives: A novel mode of action., Hondebrink L., Neurotoxicology. December 1, 2015; 51 1-9.

A novel GABA(A) alpha 5 receptor inhibitor with therapeutic potential., Ling I., Eur J Pharmacol. October 5, 2015; 764 497-507.

GABAA currents are decreased by IL-1β in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis., Roseti C., Neurobiol Dis. October 1, 2015; 82 311-320.

Direct evidence for GABAergic activity of Withania somnifera on mammalian ionotropic GABAA and GABAρ receptors., Candelario M., J Ethnopharmacol. August 2, 2015; 171 264-72.

Positive modulation of synaptic and extrasynaptic GABAA receptors by an antagonist of the high affinity benzodiazepine binding site., Middendorp SJ., Neuropharmacology. August 1, 2015; 95 459-67.

A Multifaceted GABAA Receptor Modulator: Functional Properties and Mechanism of Action of the Sedative-Hypnotic and Recreational Drug Methaqualone (Quaalude)., Hammer H., Mol Pharmacol. August 1, 2015; 88 (2): 401-20.

Re-engineering a neuroprotective, clinical drug as a procognitive agent with high in vivo potency and with GABAA potentiating activity for use in dementia., Luo J., BMC Neurosci. March 5, 2015; 16 67.        

MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity., Rosso JP., Proc Natl Acad Sci U S A. February 24, 2015; 112 (8): E891-900.

Inhibitory effects of insulin on GABAA currents modulated by the GABAA alpha subunit., Williams DB., J Recept Signal Transduct Res. January 1, 2015; 35 (6): 516-22.

Probing α4βδ GABAA receptor heterogeneity: differential regional effects of a functionally selective α4β1δ/α4β3δ receptor agonist on tonic and phasic inhibition in rat brain., Hoestgaard-Jensen K., J Neurosci. December 3, 2014; 34 (49): 16256-72.

Positive allosteric modulation of the GHB high-affinity binding site by the GABAA receptor modulator monastrol and the flavonoid catechin., Eghorn LF., Eur J Pharmacol. October 5, 2014; 740 570-7.

11-trifluoromethyl-phenyldiazirinyl neurosteroid analogues: potent general anesthetics and photolabeling reagents for GABAA receptors., Chen ZW., Psychopharmacology (Berl). September 1, 2014; 231 (17): 3479-91.

Relative positioning of classical benzodiazepines to the γ2-subunit of GABAA receptors., Middendorp SJ., ACS Chem Biol. August 15, 2014; 9 (8): 1846-53.

Engineering a light-regulated GABAA receptor for optical control of neural inhibition., Lin WC., ACS Chem Biol. July 18, 2014; 9 (7): 1414-9.        

Modulation of ionotropic GABA receptors by 6-methoxyflavanone and 6-methoxyflavone., Hall BJ., Neurochem Res. June 1, 2014; 39 (6): 1068-78.

Sh-I-048A, an in vitro non-selective super-agonist at the benzodiazepine site of GABAA receptors: the approximated activation of receptor subtypes may explain behavioral effects., Obradović ALj., Dev Biol. March 20, 2014; 1554 36-48.

Neurosteroid analogues. 18. Structure-activity studies of ent-steroid potentiators of γ-aminobutyric acid type A receptors and comparison of their activities with those of alphaxalone and allopregnanolone., Qian M., J Med Chem. January 9, 2014; 57 (1): 171-90.

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