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Temporal and spatial transcriptomic dynamics across brain development in Xenopus laevis tadpoles. , Ta AC ., G3 (Bethesda). January 4, 2022; 12 (1):
A convergent molecular network underlying autism and congenital heart disease. , Rosenthal SB., Cell Syst. November 17, 2021; 12 (11): 1094-1107.e6.
Positive allosteric modulators that target NMDA receptors rectify loss-of-function GRIN variants associated with neurological and neuropsychiatric disorders. , Tang W., Neuropharmacology. October 15, 2020; 177 108247.
De novo GRIN variants in NMDA receptor M2 channel pore-forming loop are associated with neurological diseases. , Li J., Hum Mutat. December 1, 2019; 40 (12): 2393-2413.
An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups. , Perszyk R., Elife. May 24, 2018; 7
Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology. , Ogden KK., PLoS Genet. January 17, 2017; 13 (1): e1006536.
A steroid modulatory domain in NR2A collaborates with NR1 exon-5 to control NMDAR modulation by pregnenolone sulfate and protons. , Kostakis E., J Neurochem. November 1, 2011; 119 (3): 486-96.
Amyloid β peptide oligomers directly activate NMDA receptors. , Texidó L., Cell Calcium. March 1, 2011; 49 (3): 184-90.
Soluble factors from IL-1β-stimulated astrocytes activate NR1a/ NR2B receptors: implications for HIV-1-induced neurodegeneration. , Jing T., Biochem Biophys Res Commun. November 12, 2010; 402 (2): 241-6.
Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit. , Karakas E., EMBO J. December 16, 2009; 28 (24): 3910-20.
Cloning and Phylogenetic Analysis of NMDA Receptor Subunits NR1, NR2A and NR2B in Xenopus laevis Tadpoles. , Ewald RC., Front Mol Neurosci. September 11, 2009; 2 4.
Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/ NR2B N-methyl-D-aspartate receptors. , Mosley CA., Bioorg Med Chem. September 1, 2009; 17 (17): 6463-80.
Structural basis of NR2B-selective antagonist recognition by N-methyl-D-aspartate receptors. , Mony L., Mol Pharmacol. January 1, 2009; 75 (1): 60-74.
Molecular and functional studies of tilapia (Oreochromis mossambicus) NMDA receptor NR1 subunits. , Tzeng DW., Comp Biochem Physiol B Biochem Mol Biol. March 1, 2007; 146 (3): 402-11.
Multivalent interactions of calcium/calmodulin-dependent protein kinase II with the postsynaptic density proteins NR2B, densin-180, and alpha- actinin-2. , Robison AJ., J Biol Chem. October 21, 2005; 280 (42): 35329-36.
Monoamines directly inhibit N-methyl-D-aspartate receptors expressed in Xenopus oocytes in a voltage-dependent manner. , Masuko T., Neurosci Lett. November 16, 2004; 371 (1): 30-3.
Structure-activity analysis of a novel NR2C/ NR2D-preferring NMDA receptor antagonist: 1-(phenanthrene-2-carbonyl) piperazine-2,3-dicarboxylic acid. , Feng B., Br J Pharmacol. February 1, 2004; 141 (3): 508-16.
Oxygen sensitivity of NMDA receptors: relationship to NR2 subunit composition and hypoxia tolerance of neonatal neurons. , Bickler PE., Neuroscience. January 1, 2003; 118 (1): 25-35.
N-Methyl-D-aspartate receptor subtype-selectivity of homoquinolinate: an electrophysiological and radioligand binding study using both native and recombinant receptors. , Grimwood S., J Neurochem. August 1, 2002; 82 (4): 794-800.
Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids. , Malayev A., Br J Pharmacol. February 1, 2002; 135 (4): 901-9.
Ethanol inhibition of N-methyl-D-aspartate receptors is reduced by site-directed mutagenesis of a transmembrane domain phenylalanine residue. , Ronald KM., J Biol Chem. November 30, 2001; 276 (48): 44729-35.
The anti-craving compound acamprosate acts as a weak NMDA-receptor antagonist, but modulates NMDA-receptor subunit expression similar to memantine and MK-801. , Rammes G., Neuropharmacology. May 1, 2001; 40 (6): 749-60.
Evidence for direct protein kinase-C mediated modulation of N-methyl-D-aspartate receptor current. , Liao GY., Mol Pharmacol. May 1, 2001; 59 (5): 960-4.
Use of trifluoroperazine isolates a [(3)H]Ifenprodil binding site in rat brain membranes with the pharmacology of the voltage-independent ifenprodil site on N-methyl-D-aspartate receptors containing NR2B subunits. , Coughenour LL., J Pharmacol Exp Ther. January 1, 2001; 296 (1): 150-9.
NMDA receptor subunit gene expression in the rat brain: a quantitative analysis of endogenous mRNA levels of NR1Com, NR2A, NR2B, NR2C, NR2D and NR3A. , Goebel DJ., Brain Res Mol Brain Res. June 8, 1999; 69 (2): 164-70.
Differentiation of glycine antagonist sites of N-methyl-D-aspartate receptor subtypes. Preferential interaction of CGP 61594 with NR1/2B receptors. , Honer M., J Biol Chem. May 1, 1998; 273 (18): 11158-63.
Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro. , Fischer G., J Pharmacol Exp Ther. December 1, 1997; 283 (3): 1285-92.
Pharmacological heterogeneity of NMDA receptors: characterization of NR1a/ NR2D heteromers expressed in Xenopus oocytes. , Buller AL., Eur J Pharmacol. February 5, 1997; 320 (1): 87-94.
Subtype-selective inhibition of N-methyl-D-aspartate receptors by haloperidol. , Ilyin VI., Mol Pharmacol. December 1, 1996; 50 (6): 1541-50.
Use of subunit-specific antisense oligodeoxynucleotides to define developmental changes in the properties of N-methyl-D-aspartate receptors. , Zhong J., Mol Pharmacol. September 1, 1996; 50 (3): 631-8.
Developmental and regional expression pattern of a novel NMDA receptor-like subunit ( NMDAR-L) in the rodent brain. , Sucher NJ., J Neurosci. October 1, 1995; 15 (10): 6509-20.
Spermine potentiation of recombinant N-methyl-D-aspartate receptors is affected by subunit composition. , Zhang L., Proc Natl Acad Sci U S A. November 8, 1994; 91 (23): 10883-7.
Subunit-specific potentiation of recombinant N-methyl-D-aspartate receptors by histamine. , Williams K., Mol Pharmacol. September 1, 1994; 46 (3): 531-41.
The molecular basis of NMDA receptor subtypes: native receptor diversity is predicted by subunit composition. , Buller AL., J Neurosci. September 1, 1994; 14 (9): 5471-84.