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Summary Anatomy Item Literature (86) Expression Attributions Wiki
XB-ANAT-157

Papers associated with islets of Langerhans

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A novel high-affinity inhibitor against the human ATP-sensitive Kir6.2 channel., Ramu Y., J Gen Physiol. July 2, 2018; 150 (7): 969-976.              


Binding of sulphonylureas to plasma proteins - A KATP channel perspective., Proks P., PLoS One. May 15, 2018; 13 (5): e0197634.        


Magainin-AM2 improves glucose homeostasis and beta cell function in high-fat fed mice., Ojo OO., Biochim Biophys Acta. January 1, 2015; 1850 (1): 80-7.


Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells., Oropeza D., Genesis. March 1, 2012; 50 (3): 271-85.                        


Induction of differentiation of undifferentiated cells into pancreatic beta cells in vertebrates., Hosoya M., Int J Dev Biol. January 1, 2012; 56 (5): 313-23.


Programming pluripotent precursor cells derived from Xenopus embryos to generate specific tissues and organs., Borchers A., Genes (Basel). November 18, 2010; 1 (3): 413-26.      


Disease progression and search for monogenic diabetes among children with new onset type 1 diabetes negative for ICA, GAD- and IA-2 Antibodies., Pörksen S., BMC Endocr Disord. September 23, 2010; 10 16.      


Solution structure of GxTX-1E, a high-affinity tarantula toxin interacting with voltage sensors in Kv2.1 potassium channels ., Lee S., Biochemistry. June 29, 2010; 49 (25): 5134-42.


Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes., Villasenor A., Dis Model Mech. January 1, 2010; 3 (9-10): 567-80.


The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic beta-cell line., Swayne LA., EMBO Rep. August 1, 2009; 10 (8): 873-80.        


Identification of eight new mutations in the GCK gene by DHPLC screening in a Spanish population., Solera J., Diabetes Res Clin Pract. July 1, 2009; 85 (1): 20-3.


Remodeling of insulin producing beta-cells during Xenopus laevis metamorphosis., Mukhi S., Dev Biol. April 15, 2009; 328 (2): 384-91.          


Chicoric acid, a new compound able to enhance insulin release and glucose uptake., Tousch D., Biochem Biophys Res Commun. December 5, 2008; 377 (1): 131-5.


Regulation of pancreatic beta cell mass by neuronal signals from the liver., Imai J., Science. November 21, 2008; 322 (5905): 1250-4.


Biphasic Ngn3 expression in the developing pancreas., Villasenor A., Dev Dyn. November 1, 2008; 237 (11): 3270-9.


Promoting ectopic pancreatic fates: pancreas development and future diabetes therapies., Pearl EJ., Clin Genet. October 1, 2008; 74 (4): 316-24.    


Protein expression of the transcriptional regulator MI-ER1 alpha in adult mouse tissues., Thorne LB., J Mol Histol. February 1, 2008; 39 (1): 15-24.


Functional analysis of two Kir6.2 (KCNJ11) mutations, K170T and E322K, causing neonatal diabetes., Tarasov AI., Diabetes Obes Metab. November 1, 2007; 9 Suppl 2 46-55.


Iptakalim, a vascular ATP-sensitive potassium (KATP) channel opener, closes rat pancreatic beta-cell KATP channels and increases insulin release., Misaki N., J Pharmacol Exp Ther. August 1, 2007; 322 (2): 871-8.


Scavenging of 14-3-3 proteins reveals their involvement in the cell-surface transport of ATP-sensitive K+ channels., Heusser K., J Cell Sci. October 15, 2006; 119 (Pt 20): 4353-63.


Target soluble N-ethylmaleimide-sensitive factor attachment protein receptors (t-SNAREs) differently regulate activation and inactivation gating of Kv2.2 and Kv2.1: Implications on pancreatic islet cell Kv channels., Wolf-Goldberg T., Mol Pharmacol. September 1, 2006; 70 (3): 818-28.


Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue., Afelik S., Genes Dev. June 1, 2006; 20 (11): 1441-6.                        


Functional effects of naturally occurring KCNJ11 mutations causing neonatal diabetes on cloned cardiac KATP channels., Tammaro P., J Physiol. February 15, 2006; 571 (Pt 1): 3-14.


NeuroD1 in the endocrine pancreas: localization and dual function as an activator and repressor., Itkin-Ansari P., Dev Dyn. July 1, 2005; 233 (3): 946-53.


Stichodactyla helianthus peptide, a pharmacological tool for studying Kv3.2 channels., Yan L., Mol Pharmacol. May 1, 2005; 67 (5): 1513-21.


Wolframin expression induces novel ion channel activity in endoplasmic reticulum membranes and increases intracellular calcium., Osman AA., J Biol Chem. December 26, 2003; 278 (52): 52755-62.


Potent and selective activation of the pancreatic beta-cell type K(ATP) channel by two novel diazoxide analogues., Dabrowski M., Diabetologia. October 1, 2003; 46 (10): 1375-82.


Direct interaction of target SNAREs with the Kv2.1 channel. Modal regulation of channel activation and inactivation gating., Michaelevski I., J Biol Chem. September 5, 2003; 278 (36): 34320-30.


Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides., Reimann F., J Physiol. February 15, 2003; 547 (Pt 1): 159-68.


Organogenesis: making pancreas from liver., McLin VA., Curr Biol. February 4, 2003; 13 (3): R96-8.


Phosphocreatine as a determinant of K(ATP) channel activity in pancreatic beta-cells., Krippeit-Drews P., Pflugers Arch. February 1, 2003; 445 (5): 556-62.


Comparative peptidomics of the endocrine pancreas: islet hormones from the clawed frog Xenopus laevis and the red-bellied newt Cynops pyrrhogaster., Conlon JM., J Endocrinol. December 1, 2002; 175 (3): 769-77.


Conserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6., Samaras SE., Mol Cell Biol. July 1, 2002; 22 (13): 4702-13.


The 25-kDa synaptosome-associated protein (SNAP-25) binds and inhibits delayed rectifier potassium channels in secretory cells., Ji J., J Biol Chem. June 7, 2002; 277 (23): 20195-204.


The novel diazoxide analog 3-isopropylamino-7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide is a selective Kir6.2/SUR1 channel opener., Dabrowski M., Diabetes. June 1, 2002; 51 (6): 1896-906.


Open state destabilization by ATP occupancy is mechanism speeding burst exit underlying KATP channel inhibition by ATP., Li L., J Gen Physiol. January 1, 2002; 119 (1): 105-16.                    


Identification and functional analysis of mutations in FAD-binding domain of mitochondrial glycerophosphate dehydrogenase in caucasian patients with type 2 diabetes mellitus., Gudayol M., Endocrine. October 1, 2001; 16 (1): 39-42.


Structural basis for the interference between nicorandil and sulfonylurea action., Reimann F., Diabetes. October 1, 2001; 50 (10): 2253-9.


Functional expression and characterization of a voltage-gated CaV1.3 (alpha1D) calcium channel subunit from an insulin-secreting cell line., Scholze A., Mol Endocrinol. July 1, 2001; 15 (7): 1211-21.


The imidazoline RX871024 stimulates insulin secretion in pancreatic beta-cells from mice deficient in K(ATP) channel function., Efanov AM., Biochem Biophys Res Commun. June 22, 2001; 284 (4): 918-22.


Effect of repaglinide on cloned beta cell, cardiac and smooth muscle types of ATP-sensitive potassium channels., Dabrowski M., Diabetologia. June 1, 2001; 44 (6): 747-56.


Glimepiride block of cloned beta-cell, cardiac and smooth muscle K(ATP) channels., Song DK., Br J Pharmacol. May 1, 2001; 133 (1): 193-9.


Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel., Reimann F., Br J Pharmacol. April 1, 2001; 132 (7): 1542-8.


Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes., Silva JP., Nat Genet. November 1, 2000; 26 (3): 336-40.


Nucleotide modulation of pinacidil stimulation of the cloned K(ATP) channel Kir6.2/SUR2A., Gribble FM., Mol Pharmacol. June 1, 2000; 57 (6): 1256-61.


neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas., Gradwohl G., Proc Natl Acad Sci U S A. February 15, 2000; 97 (4): 1607-11.


Granin proteins (chromogranin A and secretogranin II C23-3 and C26-3) in the endocrine pancreas of amphibians., Trandaburu T., Ann Anat. December 1, 1999; 181 (6): 585-92.


Altered functional properties of KATP channel conferred by a novel splice variant of SUR1., Sakura H., J Physiol. December 1, 1999; 521 Pt 2 337-50.


In vitro mechanism of action on insulin release of S-22068, a new putative antidiabetic compound., Le Brigand L., Br J Pharmacol. November 1, 1999; 128 (5): 1021-6.


Interaction of vanadate with the cloned beta cell K(ATP) channel., Proks P., J Biol Chem. September 3, 1999; 274 (36): 25393-7.

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