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Summary Anatomy Item Literature (6354) Expression Attributions Wiki
XB-ANAT-254

Papers associated with oocyte (and kcnh2)

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Functional and clinical characterization of a novel homozygous KCNH2 missense variant in the pore region of Kv11.1 leading to a viable but severe long-QT syndrome., Delinière A., Gene. March 1, 2024; 897 148076.


External Cd2+ and protons activate the hyperpolarization-gated K+ channel KAT1 at the voltage sensor., Zhou Y., J Gen Physiol. January 4, 2021; 153 (1):                           


Investigating the utility of adult zebrafish ex vivo whole hearts to pharmacologically screen hERG channel activator compounds., Hull CM., Am J Physiol Regul Integr Comp Physiol. December 1, 2019; 317 (6): R921-R931.


Temperature Dependence of the Biophysical Mechanisms Underlying the Inhibition and Enhancement Effect of Amiodarone on hERG Channels., Lo YC., Mol Pharmacol. September 1, 2019; 96 (3): 330-344.


Nocturnal Atrial Fibrillation Caused by Mutation in KCND2, Encoding Pore-Forming (α) Subunit of the Cardiac Kv4.2 Potassium Channel., Drabkin M., Circ Genom Precis Med. November 1, 2018; 11 (11): e002293.


Two mutations at different positions in the CNBH domain of the hERG channel accelerate deactivation and impair the interaction with the EAG domain., Kume S., J Physiol. October 1, 2018; 596 (19): 4629-4650.


Functional characterization of Kv11.1 (hERG) potassium channels split in the voltage-sensing domain., de la Peña P., Pflugers Arch. July 1, 2018; 470 (7): 1069-1085.                


Dynamic rearrangement of the intrinsic ligand regulates KCNH potassium channels., Dai G., J Gen Physiol. April 2, 2018; 150 (4): 625-635.            


The Fast Component of hERG Gating Charge: An Interaction between D411 in the S1 and S4 Residues., Dou Y., Biophys J. November 7, 2017; 113 (9): 1979-1991.


Regulation of human cardiac potassium channels by full-length KCNE3 and KCNE4., Abbott GW., Sci Rep. December 6, 2016; 6 38412.              


Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains., Lörinczi É., Nat Commun. March 30, 2015; 6 6672.                    


Xenopus borealis as an alternative source of oocytes for biophysical and pharmacological studies of neuronal ion channels., Cristofori-Armstrong B., Sci Rep. January 12, 2015; 5 14763.                                


Ginseng gintonin activates the human cardiac delayed rectifier K+ channel: involvement of Ca2+/calmodulin binding sites., Choi SH., Mol Cells. September 1, 2014; 37 (9): 656-63.                


The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT., Mechakra A., Gene. February 25, 2014; 536 (2): 348-56.            


External pH modulates EAG superfamily K+ channels through EAG-specific acidic residues in the voltage sensor., Kazmierczak M., J Gen Physiol. June 1, 2013; 141 (6): 721-35.                        


Impaired ion channel function related to a common KCNQ1 mutation - implications for risk stratification in long QT syndrome 1., Aidery P., Gene. December 10, 2012; 511 (1): 26-33.        


Kcnh1 voltage-gated potassium channels are essential for early zebrafish development., Stengel R., J Biol Chem. October 12, 2012; 287 (42): 35565-35575.            


Tuning of EAG K(+) channel inactivation: molecular determinants of amplification by mutations and a small molecule., Garg V., J Gen Physiol. September 1, 2012; 140 (3): 307-24.                            


Inhibition of cardiac Kir2.1-2.3 channels by beta3 adrenoreceptor antagonist SR 59230A., Kulzer M., Biochem Biophys Res Commun. July 27, 2012; 424 (2): 315-20.


18β-Glycyrrhetinic acid preferentially blocks late Na current generated by ΔKPQ Nav1.5 channels., Du YM., Acta Pharmacol Sin. June 1, 2012; 33 (6): 752-60.            


Stimulation of HERG channel activity by β-catenin., Munoz C., PLoS One. January 1, 2012; 7 (8): e43353.          


Differential effects of ginsenoside metabolites on HERG k channel currents., Choi SH., J Ginseng Res. June 1, 2011; 35 (2): 191-9.        


hERGAPDbase: a database documenting hERG channel inhibitory potentials and APD-prolongation activities of chemical compounds., Hishigaki H., Database (Oxford). May 17, 2011; 2011 bar017.            


Modification of hERG1 channel gating by Cd2+., Abbruzzese J., J Gen Physiol. August 1, 2010; 136 (2): 203-24.                                        


Fluorescence-tracking of activation gating in human ERG channels reveals rapid S4 movement and slow pore opening., Es-Salah-Lamoureux Z., PLoS One. May 3, 2010; 5 (5): e10876.                    


Inhibition of the human ether-a-go-go-related gene (HERG) K+ channels by Lindera erythrocarpa., Hong HK., J Korean Med Sci. December 1, 2009; 24 (6): 1089-98.            


Characterization of novel KCNH2 mutations in type 2 long QT syndrome manifesting as seizures., Keller DI., Can J Cardiol. August 1, 2009; 25 (8): 455-62.


[The persistent expression of HERG channel in Xenopus oocyte and alteration of current]., Wang XP., Zhongguo Ying Yong Sheng Li Xue Za Zhi. August 1, 2008; 24 (3): 329-33.


Inhibition of cardiac hERG potassium channels by tetracyclic antidepressant mianserin., Scherer D., Naunyn Schmiedebergs Arch Pharmacol. July 1, 2008; 378 (1): 73-83.


In vitro modulation of HERG channels by organochlorine solvent trichlormethane as potential explanation for proarrhythmic effects of chloroform., Scholz EP., Toxicol Lett. August 20, 2006; 165 (2): 156-66.


[Electrophysiological characterization of long QT syndrome associated mutations V630A and N633S]., She HR., Zhonghua Xin Xue Guan Bing Za Zhi. June 1, 2006; 34 (6): 523-7.


Atypical tetracyclic antidepressant maprotiline is an antagonist at cardiac hERG potassium channels., Kiesecker C., Naunyn Schmiedebergs Arch Pharmacol. June 1, 2006; 373 (3): 212-20.


Gating charges in the activation and inactivation processes of the HERG channel., Zhang M., J Gen Physiol. December 1, 2004; 124 (6): 703-18.                    


Identification and characterisation of a novel KCNQ1 mutation in a family with Romano-Ward syndrome., Zehelein J., Biochim Biophys Acta. November 5, 2004; 1690 (3): 185-92.


Activation properties of Kv4.3 channels: time, voltage and [K+]o dependence., Wang S., J Physiol. June 15, 2004; 557 (Pt 3): 705-17.


Inactivation gating determines drug potency: a common mechanism for drug blockade of HERG channels., Yang BF., Acta Pharmacol Sin. May 1, 2004; 25 (5): 554-60.


Gating currents associated with intramembrane charge displacement in HERG potassium channels., Piper DR., Proc Natl Acad Sci U S A. September 2, 2003; 100 (18): 10534-9.


[Electropharmacological assessment of the risk of drug-induced long-QT syndrome using native cardiac cells and cultured cells expressing HERG channels]., Nakaya H., Nihon Yakurigaku Zasshi. June 1, 2003; 121 (6): 384-92.


RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies., Anantharam A., J Biol Chem. April 4, 2003; 278 (14): 11739-45.


Structural and functional role of the extracellular s5-p linker in the HERG potassium channel., Liu J., J Gen Physiol. November 1, 2002; 120 (5): 723-37.                  


Kinetic modulation of HERG potassium channels by the volatile anesthetic halothane., Li J., Anesthesiology. October 1, 2002; 97 (4): 921-30.


Characterization of a novel missense mutation E637K in the pore-S6 loop of HERG in a patient with long QT syndrome., Hayashi K., Cardiovasc Res. April 1, 2002; 54 (1): 67-76.


Long-QT syndrome-associated missense mutations in the pore helix of the HERG potassium channel., Huang FD., Circulation. August 28, 2001; 104 (9): 1071-5.


MinK subdomains that mediate modulation of and association with KvLQT1., Tapper AR., J Gen Physiol. September 1, 2000; 116 (3): 379-90.          


Trapping of a methanesulfonanilide by closure of the HERG potassium channel activation gate., Mitcheson JS., J Gen Physiol. March 1, 2000; 115 (3): 229-40.                    


Ultrafast inactivation causes inward rectification in a voltage-gated K(+) channel from Caenorhabditis elegans., Fleischhauer R., J Neurosci. January 15, 2000; 20 (2): 511-20.


Analysis of the human KCNH2(HERG) gene: identification and characterization of a novel mutation Y667X associated with long QT syndrome and a non-pathological 9 bp insertion., Paulussen A., Hum Mutat. January 1, 2000; 15 (5): 483.


Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel., Furutani M., Circulation. May 4, 1999; 99 (17): 2290-4.


Long QT syndrome-associated mutations in the Per-Arnt-Sim (PAS) domain of HERG potassium channels accelerate channel deactivation., Chen J., J Biol Chem. April 9, 1999; 274 (15): 10113-8.


Regulation of deactivation by an amino terminal domain in human ether-à-go-go-related gene potassium channels., Wang J., J Gen Physiol. November 1, 1998; 112 (5): 637-47.              

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