Papers associated with epidermis (and kcnh2)

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	Stoichiometry of altered hERG1 channel gating by small molecule activators., Wu W., J Gen Physiol. April 1, 2014; 143 (4): 499-512.
	Blocking of the human ether-à-go-go-related gene channel by imatinib mesylate., Dong Q., Biol Pharm Bull. January 1, 2013; 36 (2): 268-75.
	A natural point mutation changes both target selectivity and mechanism of action of sea anemone toxins., Peigneur S., FASEB J. December 1, 2012; 26 (12): 5141-51.
	Tuning of EAG K(+) channel inactivation: molecular determinants of amplification by mutations and a small molecule., Garg V., J Gen Physiol. September 1, 2012; 140 (3): 307-24.
	Inhibition of cardiac Kir2.1-2.3 channels by beta3 adrenoreceptor antagonist SR 59230A., Kulzer M., Biochem Biophys Res Commun. July 27, 2012; 424 (2): 315-20.
	18β-Glycyrrhetinic acid preferentially blocks late Na current generated by ΔKPQ Nav1.5 channels., Du YM., Acta Pharmacol Sin. June 1, 2012; 33 (6): 752-60.
	A molecular switch driving inactivation in the cardiac K+ channel HERG., Köpfer DA., PLoS One. January 1, 2012; 7 (7): e41023.
	Molecular determinants for activation of human ether-à-go-go-related gene 1 potassium channels by 3-nitro-n-(4-phenoxyphenyl) benzamide., Garg V., Mol Pharmacol. October 1, 2011; 80 (4): 630-7.
	Effects of the histamine H(1) receptor antagonist hydroxyzine on hERG K(+) channels and cardiac action potential duration., Lee BH., Acta Pharmacol Sin. September 1, 2011; 32 (9): 1128-37.
	A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties., Peigneur S., Biochem Pharmacol. July 1, 2011; 82 (1): 81-90.
	A potent potassium channel blocker from Mesobuthus eupeus scorpion venom., Gao B., Biochimie. December 1, 2010; 92 (12): 1847-53.
	Aconitine blocks HERG and Kv1.5 potassium channels., Li Y., J Ethnopharmacol. August 19, 2010; 131 (1): 187-95.
	Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine., Obers S., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2010; 381 (5): 385-400.
	Block of the human ether-a-go-go-related gene (hERG) K+ channel by the antidepressant desipramine., Hong HK., Biochem Biophys Res Commun. April 9, 2010; 394 (3): 536-41.
	Block effect of capsaicin on hERG potassium currents is enhanced by S6 mutation at Y652., Xing J., Eur J Pharmacol. March 25, 2010; 630 (1-3): 1-9.
	H(1) antihistamine drug promethazine directly blocks hERG K(+) channel., Jo SH., Pharmacol Res. November 1, 2009; 60 (5): 429-37.
	Block of HERG k channel by classic histamine h(1) receptor antagonist chlorpheniramine., Hong HK., Korean J Physiol Pharmacol. June 1, 2009; 13 (3): 215-20.
	Oxycodone is associated with dose-dependent QTc prolongation in patients and low-affinity inhibiting of hERG activity in vitro., Fanoe S., Br J Clin Pharmacol. February 1, 2009; 67 (2): 172-9.
	Selective noradrenaline reuptake inhibitor atomoxetine directly blocks hERG currents., Scherer D., Br J Pharmacol. January 1, 2009; 156 (2): 226-36.
	Inhibition of cardiac hERG potassium channels by tetracyclic antidepressant mianserin., Scherer D., Naunyn Schmiedebergs Arch Pharmacol. July 1, 2008; 378 (1): 73-83.
	Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels., Cuypers E., Toxicon. May 1, 2008; 51 (6): 974-83.
	An extracellular Cu2+ binding site in the voltage sensor of BK and Shaker potassium channels., Ma Z., J Gen Physiol. May 1, 2008; 131 (5): 483-502.
	Modulation of voltage-gated Na+ and K+ channels by pumiliotoxin 251D: a "joint venture" alkaloid from arthropods and amphibians., Vandendriessche T., Toxicon. March 1, 2008; 51 (3): 334-44.
	Protriptyline block of the human ether-à-go-go-related gene (HERG) K+ channel., Jo SH., Life Sci. January 30, 2008; 82 (5-6): 331-40.
	Extracellular acidification and hyperkalemia induce changes in HERG inhibition by ibutilide., Lin C., Cardiology. January 1, 2008; 110 (3): 209-16.
	The additive effects of the active component of grapefruit juice (naringenin) and antiarrhythmic drugs on HERG inhibition., Lin C., Cardiology. January 1, 2008; 110 (3): 145-52.
	Anticholinergic antiparkinson drug orphenadrine inhibits HERG channels: block attenuation by mutations of the pore residues Y652 or F656., Scholz EP., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2007; 376 (4): 275-84.
	Verapamil blocks HERG channel by the helix residue Y652 and F656 in the S6 transmembrane domain., Duan JJ., Acta Pharmacol Sin. July 1, 2007; 28 (7): 959-67.
	Modulation of ERG channels by XE991., Elmedyb P., Basic Clin Pharmacol Toxicol. May 1, 2007; 100 (5): 316-22.
	The effect of high extracellular potassium on IKr inhibition by anti-arrhythmic agents., Lin C., Cardiology. January 1, 2007; 108 (1): 18-27.
	In vitro modulation of HERG channels by organochlorine solvent trichlormethane as potential explanation for proarrhythmic effects of chloroform., Scholz EP., Toxicol Lett. August 20, 2006; 165 (2): 156-66.
	Atypical tetracyclic antidepressant maprotiline is an antagonist at cardiac hERG potassium channels., Kiesecker C., Naunyn Schmiedebergs Arch Pharmacol. June 1, 2006; 373 (3): 212-20.
	Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine., Lee SY., Br J Pharmacol. June 1, 2006; 148 (4): 499-509.
	Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs., Perry M., Mol Pharmacol. February 1, 2006; 69 (2): 509-19.
	Block of hERG channel by ziprasidone: biophysical properties and molecular determinants., Su Z., Biochem Pharmacol. January 12, 2006; 71 (3): 278-86.
	Inhibition of human ether-a-go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine., Choi SY., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.
	Class Ia anti-arrhythmic drug ajmaline blocks HERG potassium channels: mode of action., Kiesecker C., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 423-35.
	Block of wild-type and inactivation-deficient human ether-a-go-go-related gene K+ channels by halofantrine., Sánchez-Chapula JA., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 484-91.
	Effects of the atrial antiarrhythmic drug AVE0118 on cardiac ion channels., Gögelein H., Naunyn Schmiedebergs Arch Pharmacol. September 1, 2004; 370 (3): 183-92.
	Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin., Thomas D., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2004; 369 (5): 462-72.
	Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine., Scholz EP., Naunyn Schmiedebergs Arch Pharmacol. November 1, 2003; 368 (5): 404-14.
	Inhibition of cloned HERG potassium channels by the antiestrogen tamoxifen., Thomas D., Naunyn Schmiedebergs Arch Pharmacol. July 1, 2003; 368 (1): 41-8.
	The antipsychotic drug chlorpromazine inhibits HERG potassium channels., Thomas D., Br J Pharmacol. June 1, 2003; 139 (3): 567-74.
	Voltage-dependent profile of human ether-a-go-go-related gene channel block is influenced by a single residue in the S6 transmembrane domain., Sănchez-Chapula JA., Mol Pharmacol. May 1, 2003; 63 (5): 1051-8.
	Dissociation of E-4031 from the HERG channel caused by mutations of an amino acid results in greater block at high stimulation frequency., Ishii K., Cardiovasc Res. March 1, 2003; 57 (3): 651-9.
	Inhibition of hEAG1 and hERG1 potassium channels by clofilium and its tertiary analogue LY97241., Gessner G., Br J Pharmacol. January 1, 2003; 138 (1): 161-71.
	Structural and functional role of the extracellular s5-p linker in the HERG potassium channel., Liu J., J Gen Physiol. November 1, 2002; 120 (5): 723-37.
	Bertosamil blocks HERG potassium channels in their open and inactivated states., Zitron E., Br J Pharmacol. September 1, 2002; 137 (2): 221-8.
	Molecular determinants of voltage-dependent human ether-a-go-go related gene (HERG) K+ channel block., Sánchez-Chapula JA., J Biol Chem. June 28, 2002; 277 (26): 23587-95.
	Inhibition of cardiac potassium currents by pentobarbital., Bachmann A., Naunyn Schmiedebergs Arch Pharmacol. January 1, 2002; 365 (1): 29-37.

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