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Tril dampens Nodal signaling through Pellino2- and Traf6-mediated activation of Nedd4l. , Kim HS ., Proc Natl Acad Sci U S A. September 7, 2021; 118 (36):
Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage. , Castro Colabianchi AM., Biol Open. February 25, 2021; 10 (2):
Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis. , Ding Y ., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.
A catalog of Xenopus tropicalis transcription factors and their regional expression in the early gastrula stage embryo. , Blitz IL ., Dev Biol. June 15, 2017; 426 (2): 409-417.
Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis. , Ding Y ., Proc Natl Acad Sci U S A. April 11, 2017; 114 (15): E3081-E3090.
Gtpbp2 is a positive regulator of Wnt signaling and maintains low levels of the Wnt negative regulator Axin. , Gillis WQ., Cell Commun Signal. August 2, 2016; 14 (1): 15.
Noggin4 is a long-range inhibitor of Wnt8 signalling that regulates head development in Xenopus laevis. , Eroshkin FM., Sci Rep. January 22, 2016; 6 23049.
The splicing factor PQBP1 regulates mesodermal and neural development through FGF signaling. , Iwasaki Y ., Development. October 1, 2014; 141 (19): 3740-51.
The Xenopus homologue of Down syndrome critical region protein 6 drives dorsoanterior gene expression and embryonic axis formation by antagonising polycomb group proteins. , Li HY., Development. December 1, 2013; 140 (24): 4903-13.
Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis. , Colas AR., Genes Dev. December 1, 2012; 26 (23): 2567-79.
Klf4 is required for germ-layer differentiation and body axis patterning during Xenopus embryogenesis. , Cao Q., Development. November 1, 2012; 139 (21): 3950-61.
mNanog possesses dorsal mesoderm-inducing ability by modulating both BMP and Activin/ nodal signaling in Xenopus ectodermal cells. , Miyazaki A., PLoS One. January 1, 2012; 7 (10): e46630.
Novel functions of Noggin proteins: inhibition of Activin/ Nodal and Wnt signaling. , Bayramov AV., Development. December 1, 2011; 138 (24): 5345-56.
APOBEC2, a selective inhibitor of TGFβ signaling, regulates left- right axis specification during early embryogenesis. , Vonica A ., Dev Biol. February 1, 2011; 350 (1): 13-23.
Activin/ nodal signaling modulates XPAPC expression during Xenopus gastrulation. , Lou X., Dev Dyn. March 1, 2008; 237 (3): 683-91.
Hes6 is required for MyoD induction during gastrulation. , Murai K., Dev Biol. December 1, 2007; 312 (1): 61-76.
Tsukushi modulates Xnr2, FGF and BMP signaling: regulation of Xenopus germ layer formation. , Morris SA., PLoS One. October 10, 2007; 2 (10): e1004.
FoxD3 regulation of Nodal in the Spemann organizer is essential for Xenopus dorsal mesoderm development. , Steiner AB., Development. December 1, 2006; 133 (24): 4827-38.
ADMP2 is essential for primitive blood and heart development in Xenopus. , Kumano G ., Dev Biol. November 15, 2006; 299 (2): 411-23.
Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal. , Zamparini AL., Development. September 1, 2006; 133 (18): 3709-22.
Xenopus POU factors of subclass V inhibit activin/ nodal signaling during gastrulation. , Cao Y ., Mech Dev. August 1, 2006; 123 (8): 614-25.
Nodal-related gene Xnr5 is amplified in the Xenopus genome. , Takahashi S ., Genesis. July 1, 2006; 44 (7): 309-21.
Cooperative non-cell and cell autonomous regulation of Nodal gene expression and signaling by Lefty/ Antivin and Brachyury in Xenopus. , Cha YR., Dev Biol. February 15, 2006; 290 (2): 246-64.
SOX7 and SOX18 are essential for cardiogenesis in Xenopus. , Zhang C., Dev Dyn. December 1, 2005; 234 (4): 878-91.
Xnr2 and Xnr5 unprocessed proteins inhibit Wnt signaling upstream of dishevelled. , Onuma Y ., Dev Dyn. December 1, 2005; 234 (4): 900-10.
Maternal Xenopus Zic2 negatively regulates Nodal-related gene expression during anteroposterior patterning. , Houston DW ., Development. November 1, 2005; 132 (21): 4845-55.
Xenopus hairy2b specifies anterior prechordal mesoderm identity within Spemann's organizer. , Yamaguti M., Dev Dyn. September 1, 2005; 234 (1): 102-13.
New roles for FoxH1 in patterning the early embryo. , Kofron M ., Development. October 1, 2004; 131 (20): 5065-78.
Activin redux: specification of mesodermal pattern in Xenopus by graded concentrations of endogenous activin B. , Piepenburg O., Development. October 1, 2004; 131 (20): 4977-86.
Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus. , Kuroda H ., PLoS Biol. May 1, 2004; 2 (5): E92.
The Xenopus LIM-homeodomain protein Xlim5 regulates the differential adhesion properties of early ectoderm cells. , Houston DW ., Development. June 1, 2003; 130 (12): 2695-704.
Nodal signaling in Xenopus gastrulae is cell-autonomous and patterned by beta-catenin. , Hashimoto-Partyka MK., Dev Biol. January 1, 2003; 253 (1): 125-38.
Lefty-dependent inhibition of Nodal- and Wnt-responsive organizer gene expression is essential for normal gastrulation. , Branford WW ., Curr Biol. December 23, 2002; 12 (24): 2136-41.
The nodal target gene Xmenf is a component of an FGF-independent pathway of ventral mesoderm induction in Xenopus. , Kumano G ., Mech Dev. October 1, 2002; 118 (1-2): 45-56.
The roles of three signaling pathways in the formation and function of the Spemann Organizer. , Xanthos JB., Development. September 1, 2002; 129 (17): 4027-43.
Effects of heterodimerization and proteolytic processing on Derrière and Nodal activity: implications for mesoderm induction in Xenopus. , Eimon PM., Development. July 1, 2002; 129 (13): 3089-103.
Action range of BMP is defined by its N-terminal basic amino acid core. , Ohkawara B., Curr Biol. February 5, 2002; 12 (3): 205-9.
Boundaries and functional domains in the animal/vegetal axis of Xenopus gastrula mesoderm. , Kumano G ., Dev Biol. August 15, 2001; 236 (2): 465-77.
The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development. , Reissmann E., Genes Dev. August 1, 2001; 15 (15): 2010-22.
A role for BMP signalling in heart looping morphogenesis in Xenopus. , Breckenridge RA., Dev Biol. April 1, 2001; 232 (1): 191-203.
FGF signaling restricts the primary blood islands to ventral mesoderm. , Kumano G ., Dev Biol. December 15, 2000; 228 (2): 304-14.
Endodermal Nodal-related signals and mesoderm induction in Xenopus. , Agius E ., Development. March 1, 2000; 127 (6): 1173-83.
The lefty-related factor Xatv acts as a feedback inhibitor of nodal signaling in mesoderm induction and L-R axis development in xenopus. , Cheng AM., Development. March 1, 2000; 127 (5): 1049-61.
Xenopus nodal-related signaling is essential for mesendodermal patterning during early embryogenesis. , Osada SI., Development. June 1, 1999; 126 (14): 3229-40.
derrière: a TGF-beta family member required for posterior development in Xenopus. , Sun BI., Development. April 1, 1999; 126 (7): 1467-82.
The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. , Hsu DR., Mol Cell. April 1, 1998; 1 (5): 673-83.
Establishment of a BMP-4 morphogen gradient by long-range inhibition. , Jones CM ., Dev Biol. February 1, 1998; 194 (1): 12-7.
Functional differences among Xenopus nodal-related genes in left- right axis determination. , Sampath K ., Development. September 1, 1997; 124 (17): 3293-302.
Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. , Jones CM ., Development. November 1, 1995; 121 (11): 3651-62.