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Gtpbp2 is required for BMP signaling and mesoderm patterning in Xenopus embryos. , Kirmizitas A., Dev Biol. August 15, 2014; 392 (2): 358-67.
Signaling crosstalk between TGFβ and Dishevelled/ Par1b. , Mamidi A., Cell Death Differ. October 1, 2012; 19 (10): 1689-97.
Dynamics of TGF-β signaling reveal adaptive and pulsatile behaviors reflected in the nuclear localization of transcription factor Smad4. , Warmflash A., Proc Natl Acad Sci U S A. July 10, 2012; 109 (28): E1947-56.
The BMP pathway acts to directly regulate Tbx20 in the developing heart. , Mandel EM ., Development. June 1, 2010; 137 (11): 1919-29.
Modeling and analysis of MH1 domain of Smads and their interaction with promoter DNA sequence motif. , Makkar P., J Mol Graph Model. April 1, 2009; 27 (7): 803-12.
Nuclear accumulation of Smad complexes occurs only after the midblastula transition in Xenopus. , Saka Y ., Development. December 1, 2007; 134 (23): 4209-18.
The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter. , Grocott T., Nucleic Acids Res. January 1, 2007; 35 (3): 890-901.
Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor beta-dependent nuclear accumulation of Smads. , Schmierer B., Mol Cell Biol. November 1, 2005; 25 (22): 9845-58.
Notch signaling modulates the nuclear localization of carboxy-terminal-phosphorylated smad2 and controls the competence of ectodermal cells for activin A. , Abe T., Mech Dev. May 1, 2005; 122 (5): 671-80.
Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase. , Dupont S., Cell. April 8, 2005; 121 (1): 87-99.
MAB21L2, a vertebrate member of the Male-abnormal 21 family, modulates BMP signaling and interacts with SMAD1. , Baldessari D., BMC Cell Biol. December 21, 2004; 5 (1): 48.
Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells. , De Bosscher K., Biochem J. April 1, 2004; 379 (Pt 1): 209-16.
[The role of Smads and related transcription factors in the signal transduction of bone morphogenetic protein inducing bone formation]. , Xu XL., Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. September 1, 2003; 17 (5): 359-62.
Sumoylation of Smad4, the common Smad mediator of transforming growth factor-beta family signaling. , Lee PS., J Biol Chem. July 25, 2003; 278 (30): 27853-63.
Negative regulation of BMP signaling by the ski oncoprotein. , Luo K., J Bone Joint Surg Am. January 1, 2003; 85-A Suppl 3 39-43.
Stoichiometry of active smad-transcription factor complexes on DNA. , Inman GJ., J Biol Chem. December 27, 2002; 277 (52): 51008-16.
Expression cloning of Xenopus Os4, an evolutionarily conserved gene, which induces mesoderm and dorsal axis. , Zohn IE., Dev Biol. November 1, 2001; 239 (1): 118-31.
The transcriptional role of Smads and FAST ( FoxH1) in TGFbeta and activin signalling. , Attisano L., Mol Cell Endocrinol. June 30, 2001; 180 (1-2): 3-11.
Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells. , Wang W., Proc Natl Acad Sci U S A. December 19, 2000; 97 (26): 14394-9.
Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus. , Pierreux CE., Mol Cell Biol. December 1, 2000; 20 (23): 9041-54.
Identification and characterization of constitutively active Smad2 mutants: evaluation of formation of Smad complex and subcellular distribution. , Funaba M., Mol Endocrinol. October 1, 2000; 14 (10): 1583-91.
Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer. , Nishita M., Nature. February 17, 2000; 403 (6771): 781-5.
Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif. , Germain S., Genes Dev. February 15, 2000; 14 (4): 435-51.
Activation of Stat3 by cytokine receptor gp130 ventralizes Xenopus embryos independent of BMP-4. , Nishinakamura R., Dev Biol. December 15, 1999; 216 (2): 481-90.
Xenopus Smad4beta is the co-Smad component of developmentally regulated transcription factor complexes responsible for induction of early mesodermal genes. , Howell M., Dev Biol. October 15, 1999; 214 (2): 354-69.
A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation. , Zhu H., Nature. August 12, 1999; 400 (6745): 687-93.
Dominant-negative Smad2 mutants inhibit activin/ Vg1 signaling and disrupt axis formation in Xenopus. , Hoodless PA., Dev Biol. March 15, 1999; 207 (2): 364-79.
FAST-2 is a mammalian winged-helix protein which mediates transforming growth factor beta signals. , Liu B., Mol Cell Biol. January 1, 1999; 19 (1): 424-30.
SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor. , Tsukazaki T., Cell. December 11, 1998; 95 (6): 779-91.
Smad6 inhibits BMP/ Smad1 signaling by specifically competing with the Smad4 tumor suppressor. , Hata A., Genes Dev. January 15, 1998; 12 (2): 186-97.
Dual role of the Smad4/ DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes. , Liu F., Genes Dev. December 1, 1997; 11 (23): 3157-67.
Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling. , Nakao A., Nature. October 9, 1997; 389 (6651): 631-5.
TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4. , Nakao A., EMBO J. September 1, 1997; 16 (17): 5353-62.
Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. , Lagna G., Nature. October 31, 1996; 383 (6603): 832-6.
A human Mad protein acting as a BMP-regulated transcriptional activator. , Liu F., Nature. June 13, 1996; 381 (6583): 620-3.