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Discovery of a genetic module essential for assigning left- right asymmetry in humans and ancestral vertebrates. , Szenker-Ravi E., Nat Genet. January 1, 2022; 54 (1): 62-72.
Bicc1 and Dicer regulate left- right patterning through post-transcriptional control of the Nodal inhibitor Dand5. , Maerker M., Nat Commun. September 16, 2021; 12 (1): 5482.
A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts. , Grosch M., J Cell Sci. August 15, 2021; 134 (16):
Aquatic models of human ciliary diseases. , Corkins ME., Genesis. February 1, 2021; 59 (1-2): e23410.
The ion channel function of polycystin-1 in the polycystin-1/polycystin-2 complex. , Wang Z., EMBO Rep. November 5, 2019; 20 (11): e48336.
Mechanical strain, novel genes and evolutionary insights: news from the frog left- right organizer. , Blum M ., Curr Opin Genet Dev. June 1, 2019; 56 8-14.
A PKD1L3 splice variant in taste buds is not cleaved at the G protein-coupled receptor proteolytic site. , Kashyap P., Biochem Biophys Res Commun. May 14, 2019; 512 (4): 812-818.
A dual function of FGF signaling in Xenopus left- right axis formation. , Schneider I., Development. May 10, 2019; 146 (9):
Characterization of potential TRPP2 regulating proteins in early Xenopus embryos. , Futel M., J Cell Biochem. December 1, 2018; 119 (12): 10338-10350.
An Early Function of Polycystin-2 for Left- Right Organizer Induction in Xenopus. , Vick P ., iScience. April 27, 2018; 2 76-85.
TRPP2-dependent Ca2+ signaling in dorso- lateral mesoderm is required for kidney field establishment in Xenopus. , Futel M., J Cell Sci. March 1, 2015; 128 (5): 888-99.
The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality. , Boskovski MT., Nature. December 19, 2013; 504 (7480): 456-9.
Left- right asymmetry: lessons from Cancún. , Burdine RD., Development. November 1, 2013; 140 (22): 4465-70.
Polycystin-2 activity is controlled by transcriptional coactivator with PDZ binding motif and PALS1-associated tight junction protein. , Duning K., J Biol Chem. October 29, 2010; 285 (44): 33584-8.
The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity. , Tran U ., Development. April 1, 2010; 137 (7): 1107-16.
Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants. , Sullivan-Brown J., Dev Biol. February 15, 2008; 314 (2): 261-75.
Cilia-driven leftward flow determines laterality in Xenopus. , Schweickert A ., Curr Biol. January 9, 2007; 17 (1): 60-6.
Polycystin 2 interacts with type I inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling. , Li Y., J Biol Chem. December 16, 2005; 280 (50): 41298-306.
Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis. , Bisgrove BW., Dev Biol. November 15, 2005; 287 (2): 274-88.
Localization and loss-of-function implicates ciliary proteins in early, cytoplasmic roles in left- right asymmetry. , Qiu D., Dev Dyn. September 1, 2005; 234 (1): 176-89.
Xenopus TRPN1 ( NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner- ear hair cells. , Shin JB., Proc Natl Acad Sci U S A. August 30, 2005; 102 (35): 12572-7.
A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney. , Sun Z., Development. August 1, 2004; 131 (16): 4085-93.
Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization. , Cano DA., Development. July 1, 2004; 131 (14): 3457-67.
Native polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epithelia. , Luo Y., Mol Cell Biol. April 1, 2003; 23 (7): 2600-7.