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Foxd4l1.1 Negatively Regulates Chordin Transcription in Neuroectoderm of Xenopus Gastrula. , Kumar V ., Cells. October 17, 2021; 10 (10):
Tril dampens Nodal signaling through Pellino2- and Traf6-mediated activation of Nedd4l. , Kim HS ., Proc Natl Acad Sci U S A. September 7, 2021; 118 (36):
Repression of Inappropriate Gene Expression in the Vertebrate Embryonic Ectoderm. , Reich S., Genes (Basel). November 6, 2019; 10 (11):
Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage. , Kirmizitas A., Proc Natl Acad Sci U S A. June 6, 2017; 114 (23): 5814-5821.
Loss of expression of protein phosphatase magnesium-dependent 1A during kidney injury promotes fibrotic maladaptive repair. , Samarakoon R., FASEB J. October 1, 2016; 30 (10): 3308-3320.
Small C-terminal Domain Phosphatase 3 Dephosphorylates the Linker Sites of Receptor-regulated Smads (R-Smads) to Ensure Transforming Growth Factor β (TGFβ)-mediated Germ Layer Induction in Xenopus Embryos. , Sun G ., J Biol Chem. July 10, 2015; 290 (28): 17239-49.
The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation. , Acosta H., Development. March 15, 2015; 142 (6): 1146-58.
E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation. , Wills AE ., Dev Cell. February 9, 2015; 32 (3): 345-57.
In vivo T-box transcription factor profiling reveals joint regulation of embryonic neuromesodermal bipotency. , Gentsch GE ., Cell Rep. September 26, 2013; 4 (6): 1185-96.
Signaling crosstalk between TGFβ and Dishevelled/ Par1b. , Mamidi A., Cell Death Differ. October 1, 2012; 19 (10): 1689-97.
Eps15R is required for bone morphogenetic protein signalling and differentially compartmentalizes with Smad proteins. , Callery EM ., Open Biol. April 1, 2012; 2 (4): 120060.
mNanog possesses dorsal mesoderm-inducing ability by modulating both BMP and Activin/ nodal signaling in Xenopus ectodermal cells. , Miyazaki A., PLoS One. January 1, 2012; 7 (10): e46630.
Sortilin associates with transforming growth factor-beta family proteins to enhance lysosome-mediated degradation. , Kwon S., J Biol Chem. June 17, 2011; 286 (24): 21876-85.
SNW1 is a critical regulator of spatial BMP activity, neural plate border formation, and neural crest specification in vertebrate embryos. , Wu MY., PLoS Biol. February 15, 2011; 9 (2): e1000593.
FAM/ USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination. , Dupont S., Cell. January 9, 2009; 136 (1): 123-35.
Regulation of TGF-(beta) signalling by N-acetylgalactosaminyltransferase-like 1. , Herr P., Development. May 1, 2008; 135 (10): 1813-22.
TGF-beta signaling is required for multiple processes during Xenopus tail regeneration. , Ho DM., Dev Biol. March 1, 2008; 315 (1): 203-16.
Coordination of cell polarity during Xenopus gastrulation. , Shindo A., PLoS One. February 6, 2008; 3 (2): e1600.
Neural induction requires continued suppression of both Smad1 and Smad2 signals during gastrulation. , Chang C ., Development. November 1, 2007; 134 (21): 3861-72.
Endofin acts as a Smad anchor for receptor activation in BMP signaling. , Shi W., J Cell Sci. April 1, 2007; 120 (Pt 7): 1216-24.
Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways. , Sapkota G., J Biol Chem. December 29, 2006; 281 (52): 40412-9.
FoxD3 regulation of Nodal in the Spemann organizer is essential for Xenopus dorsal mesoderm development. , Steiner AB., Development. December 1, 2006; 133 (24): 4827-38.
Dullard promotes degradation and dephosphorylation of BMP receptors and is required for neural induction. , Satow R., Dev Cell. December 1, 2006; 11 (6): 763-74.
Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling. , Knockaert M., Proc Natl Acad Sci U S A. August 8, 2006; 103 (32): 11940-5.
Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1. , Alliston T., J Biol Chem. June 24, 2005; 280 (25): 24227-37.
Notch signaling modulates the nuclear localization of carboxy-terminal-phosphorylated smad2 and controls the competence of ectodermal cells for activin A. , Abe T., Mech Dev. May 1, 2005; 122 (5): 671-80.
XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGFbeta proteins in Xenopus development. , Birsoy B., Development. February 1, 2005; 132 (3): 591-602.
Conditional BMP inhibition in Xenopus reveals stage-specific roles for BMPs in neural and neural crest induction. , Wawersik S., Dev Biol. January 15, 2005; 277 (2): 425-42.
Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling. , Mochizuki T., J Biol Chem. July 23, 2004; 279 (30): 31568-74.
Interaction with Smad4 is indispensable for suppression of BMP signaling by c- Ski. , Takeda M., Mol Biol Cell. March 1, 2004; 15 (3): 963-72.
Lefty blocks a subset of TGFbeta signals by antagonizing EGF- CFC coreceptors. , Cheng SK., PLoS Biol. February 1, 2004; 2 (2): E30.
[The role of Smads and related transcription factors in the signal transduction of bone morphogenetic protein inducing bone formation]. , Xu XL., Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. September 1, 2003; 17 (5): 359-62.
The nodal target gene Xmenf is a component of an FGF-independent pathway of ventral mesoderm induction in Xenopus. , Kumano G ., Mech Dev. October 1, 2002; 118 (1-2): 45-56.
The roles of three signaling pathways in the formation and function of the Spemann Organizer. , Xanthos JB., Development. September 1, 2002; 129 (17): 4027-43.
A component of the ARC/Mediator complex required for TGF beta/ Nodal signalling. , Kato Y ., Nature. August 8, 2002; 418 (6898): 641-6.
Beta-catenin, MAPK and Smad signaling during early Xenopus development. , Schohl A ., Development. January 1, 2002; 129 (1): 37-52.
Xenopus Smad3 is specifically expressed in the chordoneural hinge, notochord and in the endocardium of the developing heart. , Howell M., Mech Dev. June 1, 2001; 104 (1-2): 147-50.
Swift is a novel BRCT domain coactivator of Smad2 in transforming growth factor beta signaling. , Shimizu K., Mol Cell Biol. June 1, 2001; 21 (12): 3901-12.
Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase. , Zhang Y , Zhang Y ., Proc Natl Acad Sci U S A. January 30, 2001; 98 (3): 974-9.
Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads. , Kumar A., J Biol Chem. January 5, 2001; 276 (1): 656-61.
Calmodulin differentially modulates Smad1 and Smad2 signaling. , Scherer A., J Biol Chem. December 29, 2000; 275 (52): 41430-8.
Recombinant expression and purification of smad proteins. , Funaba M., Protein Expr Purif. December 1, 2000; 20 (3): 507-13.
Mesendoderm induction and reversal of left- right pattern by mouse Gdf1, a Vg1-related gene. , Wall NA., Dev Biol. November 15, 2000; 227 (2): 495-509.
Identification and characterization of constitutively active Smad2 mutants: evaluation of formation of Smad complex and subcellular distribution. , Funaba M., Mol Endocrinol. October 1, 2000; 14 (10): 1583-91.
Gli2 functions in FGF signaling during antero- posterior patterning. , Brewster R ., Development. October 1, 2000; 127 (20): 4395-405.
Fast1 is required for the development of dorsal axial structures in zebrafish. , Sirotkin HI., Curr Biol. September 7, 2000; 10 (17): 1051-4.
Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development. , Faure S ., Development. July 1, 2000; 127 (13): 2917-31.
Activation of Stat3 by cytokine receptor gp130 ventralizes Xenopus embryos independent of BMP-4. , Nishinakamura R., Dev Biol. December 15, 1999; 216 (2): 481-90.
A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation. , Zhu H., Nature. August 12, 1999; 400 (6745): 687-93.
Identification of two Smad4 proteins in Xenopus. Their common and distinct properties. , Masuyama N., J Biol Chem. April 23, 1999; 274 (17): 12163-70.