???pagination.result.count???
Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome KCNQ1 Variants. , Rinné S., Int J Mol Sci. January 10, 2023; 24 (2):
Virus-Host Interactions of Enteroviruses and Parvovirus B19 in Myocarditis. , Ho HT., Cell Physiol Biochem. November 18, 2021; 55 (6): 679-703.
Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects. , Lin Y., Proc Natl Acad Sci U S A. May 18, 2021; 118 (20):
Deconstruction of an African folk medicine uncovers a novel molecular strategy for therapeutic potassium channel activation. , De Silva AM., Sci Adv. November 14, 2018; 4 (11): eaav0824.
Direct neurotransmitter activation of voltage-gated potassium channels. , Manville RW., Nat Commun. May 10, 2018; 9 (1): 1847.
Pro-arrhythmogenic Effects of the V141M KCNQ1 Mutation in Short QT Syndrome and Its Potential Therapeutic Targets: Insights from Modeling. , Lee HC , Lee HC ., J Med Biol Eng. October 1, 2017; 37 (5): 780-789.
The residue I257 at S4-S5 linker in KCNQ1 determines KCNQ1/ KCNE1 channel sensitivity to 1-alkanols. , Xie C., Acta Pharmacol Sin. January 1, 2016; 37 (1): 124-33.
Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel. , Liin SI., Proc Natl Acad Sci U S A. May 5, 2015; 112 (18): 5714-9.
Ginseng gintonin activates the human cardiac delayed rectifier K+ channel: involvement of Ca2+/calmodulin binding sites. , Choi SH., Mol Cells. September 1, 2014; 37 (9): 656-63.
Functional assembly of Kv7.1/ Kv7.5 channels with emerging properties on vascular muscle physiology. , Oliveras A., Arterioscler Thromb Vasc Biol. July 1, 2014; 34 (7): 1522-30.
Insulin suppresses IKs ( KCNQ1/ KCNE1) currents, which require β-subunit KCNE1. , Wu M., Pflugers Arch. May 1, 2014; 466 (5): 937-46.
Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channel. , Zaydman MA., Elife. March 12, 2014; 3 e03606.
Intracellular ATP binding is required to activate the slowly activating K+ channel I(Ks). , Li Y., Proc Natl Acad Sci U S A. November 19, 2013; 110 (47): 18922-7.
Differential effects of ginsenoside metabolites on slowly activating delayed rectifier K(+) and KCNQ1 K(+) channel currents. , Choi SH., J Ginseng Res. July 1, 2013; 37 (3): 324-31.
Role of the Rap2/ TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling. , Park DS., Biochem Biophys Res Commun. June 28, 2013; 436 (2): 338-43.
Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels. , Krzystanek K., Heart Rhythm. March 1, 2012; 9 (3): 440-8.
Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation. , Daulat AM., Mol Cell Biol. January 1, 2012; 32 (1): 173-85.
Regulation of KCNQ1/ KCNE1 by β-catenin. , Wilmes J., Mol Membr Biol. January 1, 2012; 29 (3-4): 87-94.
Involvement of the eukaryotic initiation factor 6 and kermit2/ gipc2 in Xenopus laevis pronephros formation. , Tussellino M., Int J Dev Biol. January 1, 2012; 56 (5): 357-62.
Agonistic and antagonistic roles for TNIK and MINK in non-canonical and canonical Wnt signalling. , Mikryukov A., PLoS One. January 1, 2012; 7 (9): e43330.
Reconstitution of KCNE1 into lipid bilayers: comparing the structural, dynamic, and activity differences in micelle and vesicle environments. , Coey AT., Biochemistry. December 20, 2011; 50 (50): 10851-9.
KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue. , Nakajo K., J Gen Physiol. November 1, 2011; 138 (5): 521-35.
Inhibition of the heterotetrameric K+ channel KCNQ1/ KCNE1 by the AMP-activated protein kinase. , Alesutan I., Mol Membr Biol. February 1, 2011; 28 (2): 79-89.
Transmembrane potential of GlyCl-expressing instructor cells induces a neoplastic-like conversion of melanocytes via a serotonergic pathway. , Blackiston D ., Dis Model Mech. January 1, 2011; 4 (1): 67-85.
Stoichiometry of the KCNQ1 - KCNE1 ion channel complex. , Nakajo K., Proc Natl Acad Sci U S A. November 2, 2010; 107 (44): 18862-7.
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits. , Haitin Y., EMBO J. July 22, 2009; 28 (14): 1994-2005.
PKC activation and PIP(2) depletion underlie biphasic regulation of IKs by Gq-coupled receptors. , Matavel A., J Mol Cell Cardiol. May 1, 2009; 46 (5): 704-12.
Functional implications of KCNE subunit expression for the Kv7.5 ( KCNQ5) channel. , Roura-Ferrer M., Cell Physiol Biochem. January 1, 2009; 24 (5-6): 325-34.
Modulation of potassium channel function confers a hyperproliferative invasive phenotype on embryonic stem cells. , Morokuma J., Proc Natl Acad Sci U S A. October 28, 2008; 105 (43): 16608-13.
Mechanisms by which atrial fibrillation-associated mutations in the S1 domain of KCNQ1 slow deactivation of IKs channels. , Restier L., J Physiol. September 1, 2008; 586 (17): 4179-91.
KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains. , Xu X., J Gen Physiol. June 1, 2008; 131 (6): 589-603.
Counting membrane-embedded KCNE beta-subunits in functioning K+ channel complexes. , Morin TJ., Proc Natl Acad Sci U S A. February 5, 2008; 105 (5): 1478-82.
Chlorthalidone inhibits the KvLQT1 potassium current in guinea-pig ventricular myocytes and oocytes from Xenopus laevis. , Mancilla-Simbro C., Br J Pharmacol. February 1, 2008; 153 (3): 448-58.
KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval. , Lundby A., Heart Rhythm. December 1, 2007; 4 (12): 1532-41.
Serial perturbation of MinK in IKs implies an alpha-helical transmembrane span traversing the channel corpus. , Chen H ., Biophys J. October 1, 2007; 93 (7): 2332-40.
KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channel. , Nakajo K., J Gen Physiol. September 1, 2007; 130 (3): 269-81.
A derivatized scorpion toxin reveals the functional output of heteromeric KCNQ1-KCNE K+ channel complexes. , Morin TJ., ACS Chem Biol. July 20, 2007; 2 (7): 469-73.
Upregulation of KCNE1 induces QT interval prolongation in patients with chronic heart failure. , Watanabe E., Circ J. April 1, 2007; 71 (4): 471-8.
The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes. , Panaghie G., J Gen Physiol. February 1, 2007; 129 (2): 121-33.
KCNE2 is colocalized with KCNQ1 and KCNE1 in cardiac myocytes and may function as a negative modulator of I(Ks) current amplitude in the heart. , Wu DM., Heart Rhythm. December 1, 2006; 3 (12): 1469-80.
Skipping of Exon 1 in the KCNQ1 gene causes Jervell and Lange-Nielsen syndrome. , Zehelein J., J Biol Chem. November 17, 2006; 281 (46): 35397-403.
Ancillary subunits and stimulation frequency determine the potency of chromanol 293B block of the KCNQ1 potassium channel. , Bett GC., J Physiol. November 1, 2006; 576 (Pt 3): 755-67.
Frequency-dependent modulation of KCNQ1 and HERG1 potassium channels. , Diness TG., Biochem Biophys Res Commun. May 19, 2006; 343 (4): 1224-33.
Endogenous KCNE subunits govern Kv2.1 K+ channel activation kinetics in Xenopus oocyte studies. , Gordon E., Biophys J. February 15, 2006; 90 (4): 1223-31.
De novo KCNQ1 mutation responsible for atrial fibrillation and short QT syndrome in utero. , Hong K., Cardiovasc Res. December 1, 2005; 68 (3): 433-40.
Mutation of colocalized residues of the pore helix and transmembrane segments S5 and S6 disrupt deactivation and modify inactivation of KCNQ1 K+ channels. , Seebohm G ., J Physiol. March 1, 2005; 563 (Pt 2): 359-68.
Cross-talk between beta(1)-adrenoceptors and ET(A) receptors in modulation of the slow component of delayed rectifier K(+) currents. , Lin C., Naunyn Schmiedebergs Arch Pharmacol. February 1, 2005; 371 (2): 133-40.
Analysis of QT Interval Prolongation With Heart Failure by Simulation of Repolarization Process. , Yamaguchi T., Conf Proc IEEE Eng Med Biol Soc. January 1, 2005; 2005 7309-12.
Identification and characterisation of a novel KCNQ1 mutation in a family with Romano-Ward syndrome. , Zehelein J., Biochim Biophys Acta. November 5, 2004; 1690 (3): 185-92.
Ranolazine: ion-channel-blocking actions and in vivo electrophysiological effects. , Schram G., Br J Pharmacol. August 1, 2004; 142 (8): 1300-8.