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Licorice metabolite 18β-glycyrrhetinic acid activates G protein-gated inwardly rectifying K+ channels. , Chen IS., Br J Pharmacol. February 1, 2024; 181 (3): 447-463.
Dopamine-induced arrestin recruitment and desensitization of the dopamine D4 receptor is regulated by G protein-coupled receptor kinase-2. , Burström V., Front Pharmacol. January 1, 2023; 14 1087171.
The activity of the serotonergic 5-HT1A receptor is modulated by voltage and sodium levels. , Tauber M., J Biol Chem. June 1, 2022; 298 (6): 101978.
Voltage dependence of the cannabinoid CB1 receptor. , Goldberger E., Front Pharmacol. January 1, 2022; 13 1022275.
WIN55,212-2, a Dual Modulator of Cannabinoid Receptors and G Protein-Coupled Inward Rectifier Potassium Channels. , An D., Biomedicines. April 28, 2021; 9 (5):
Identification of a unique endoplasmic retention motif in the Xenopus GIRK5 channel and its contribution to oocyte maturation. , Rangel-Garcia CI., FEBS Open Bio. April 1, 2021; 11 (4): 1093-1108.
Ligand with Two Modes of Interaction with the Dopamine D2 Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism. , Ågren R., ACS Chem Neurosci. October 7, 2020; 11 (19): 3130-3143.
Sodium ions allosterically modulate the M2 muscarinic receptor. , Friedman S., Sci Rep. July 7, 2020; 10 (1): 11177.
A Collision Coupling Model Governs the Activation of Neuronal GIRK1/2 Channels by Muscarinic-2 Receptors. , Berlin S., Front Pharmacol. April 7, 2020; 11 1216.
Hydrogen Sulfide Impairs Meiosis Resumption in Xenopuslaevis Oocytes. , Gelaude A., Cells. January 17, 2020; 9 (1):
The coupling of the M2 muscarinic receptor to its G protein is voltage dependent. , Ben-Chaim Y., PLoS One. October 31, 2019; 14 (10): e0224367.
Non-sedating antihistamines block G-protein-gated inwardly rectifying K+ channels. , Chen IS., Br J Pharmacol. September 1, 2019; 176 (17): 3161-3179.
A Photoswitchable Agonist for the Histamine H3 Receptor, a Prototypic Family A G-Protein-Coupled Receptor. , Hauwert NJ., Angew Chem Int Ed Engl. March 26, 2019; 58 (14): 4531-4535.
Mutual action by Gγ and Gβ for optimal activation of GIRK channels in a channel subunit-specific manner. , Tabak G., Sci Rep. January 24, 2019; 9 (1): 508.
The Beta- Arrestin-Biased Dopamine D2 Receptor Ligand, UNC9994, Is a Partial Agonist at G-Protein-Mediated Potassium Channel Activation. , Ågren R., Int J Neuropsychopharmacol. December 1, 2018; 21 (12): 1102-1108.
Point mutation of a conserved aspartate, D69, in the muscarinic M 2 receptor does not modify voltage-sensitive agonist potency. , Ågren R., Biochem Biophys Res Commun. January 29, 2018; 496 (1): 101-104.
Structural determinants at the M2 muscarinic receptor modulate the RGS4- GIRK response to pilocarpine by impairment of the receptor voltage sensitivity. , Chen IS., Sci Rep. July 21, 2017; 7 (1): 6110.
Cholesterol up-regulates neuronal G protein-gated inwardly rectifying potassium (GIRK) channel activity in the hippocampus. , Bukiya AN., J Biol Chem. April 14, 2017; 292 (15): 6135-6147.
Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors. , Levitz J., Neuron. October 5, 2016; 92 (1): 143-159.
GIRK Channels Mediate the Nonphotic Effects of Exogenous Melatonin. , Hablitz LM., J Neurosci. November 11, 2015; 35 (45): 14957-65.
A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ. , Yakubovich D., PLoS Comput Biol. November 6, 2015; 11 (11): e1004598.
Differential effects of genetically-encoded Gβγ scavengers on receptor-activated and basal Kir3.1/ Kir3.4 channel current in rat atrial myocytes. , Kienitz MC., Cell Signal. June 1, 2014; 26 (6): 1182-1192.
RGS4 regulates partial agonism of the M2 muscarinic receptor-activated K+ currents. , Chen IS., J Physiol. March 15, 2014; 592 (6): 1237-48.
Voltage affects the dissociation rate constant of the m2 muscarinic receptor. , Ben Chaim Y., PLoS One. September 3, 2013; 8 (9): e74354.
The polarization of the G-protein activated potassium channel GIRK5 to the vegetal pole of Xenopus laevis oocytes is driven by a di-leucine motif. , Díaz-Bello B., PLoS One. May 15, 2013; 8 (5): e64096.
Molecular basis of the facilitation of the heterooligomeric GIRK1/ GIRK4 complex by cAMP dependent protein kinase. , Treiber F., Biochim Biophys Acta. April 1, 2013; 1828 (4): 1214-21.
RGS proteins maintain robustness of GPCR- GIRK coupling by selective stimulation of the G protein subunit Gαo. , Chuang HH., Sci Signal. February 21, 2012; 5 (212): ra15.
Engineering of an artificial light-modulated potassium channel. , Caro LN., PLoS One. January 1, 2012; 7 (8): e43766.
Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1. , Raphemot R., Front Pharmacol. November 30, 2011; 2 75.
β2-Adrenergic ion-channel coupled receptors as conformational motion detectors. , Caro LN., PLoS One. March 9, 2011; 6 (3): e18226.
Inhibition of g protein-activated inwardly rectifying k channels by phencyclidine. , Kobayashi T., Curr Neuropharmacol. March 1, 2011; 9 (1): 244-6.
Identification of selective agonists and antagonists to g protein-activated inwardly rectifying potassium channels: candidate medicines for drug dependence and pain. , Nishizawa D., Curr Neuropharmacol. March 1, 2011; 9 (1): 113-7.
Four and a half LIM protein 1C (FHL1C): a binding partner for voltage-gated potassium channel K( v1.5). , Poparic I., PLoS One. January 1, 2011; 6 (10): e26524.
Inhibition of G protein-activated inwardly rectifying K+ channels by different classes of antidepressants. , Kobayashi T., PLoS One. January 1, 2011; 6 (12): e28208.
Intron 4 containing novel GABAB1 isoforms impair GABAB receptor function. , Lee C , Lee C ., PLoS One. November 16, 2010; 5 (11): e14044.
Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective norepinephrine reuptake inhibitors atomoxetine and reboxetine. , Kobayashi T., Neuropsychopharmacology. June 1, 2010; 35 (7): 1560-9.
Pregnenolone sulfate potentiates the inwardly rectifying K channel Kir2.3. , Kobayashi T., PLoS One. July 21, 2009; 4 (7): e6311.
Inhibitory effects of the antiepileptic drug ethosuximide on G protein-activated inwardly rectifying K+ channels. , Kobayashi T., Neuropharmacology. February 1, 2009; 56 (2): 499-506.
Agonist and antagonist properties of antipsychotics at human dopamine D4.4 receptors: G-protein activation and K+ channel modulation in transfected cells. , Newman-Tancredi A., Int J Neuropsychopharmacol. May 1, 2008; 11 (3): 293-307.
Subunit stoichiometry of heterologously expressed G-protein activated inwardly rectifying potassium channels analysed by fluorescence intensity ratio measurement. , Grasser E., Pflugers Arch. March 1, 2008; 455 (6): 1017-24.
Inhibition by cocaine of G protein-activated inwardly rectifying K+ channels expressed in Xenopus oocytes. , Kobayashi T., Toxicol In Vitro. June 1, 2007; 21 (4): 656-64.
Functional activation by central monoamines of human dopamine D(4) receptor polymorphic variants coupled to GIRK channels in Xenopus oocytes. , Wedemeyer C., Eur J Pharmacol. May 21, 2007; 562 (3): 165-73.
Differential agonist and inverse agonist profile of antipsychotics at D2L receptors coupled to GIRK potassium channels. , Heusler P., Neuropharmacology. March 1, 2007; 52 (4): 1106-13.
Testosterone and progesterone rapidly attenuate plasma membrane Gbetagamma-mediated signaling in Xenopus laevis oocytes by signaling through classical steroid receptors. , Evaul K., Mol Endocrinol. January 1, 2007; 21 (1): 186-96.
Inhibition of G protein-activated inwardly rectifying K+ channels by the antidepressant paroxetine. , Kobayashi T., J Pharmacol Sci. November 1, 2006; 102 (3): 278-87.
Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells. , Rebois RV., J Cell Sci. July 1, 2006; 119 (Pt 13): 2807-18.
Inhibition of G protein-activated inwardly rectifying K+ channels by ifenprodil. , Kobayashi T., Neuropsychopharmacology. March 1, 2006; 31 (3): 516-24.
Tyrosine phosphorylation of K(ir)3.1 in spinal cord is induced by acute inflammation, chronic neuropathic pain, and behavioral stress. , Ippolito DL., J Biol Chem. December 16, 2005; 280 (50): 41683-93.
Gbetagamma-dependent and Gbetagamma-independent basal activity of G protein-activated K+ channels. , Rishal I., J Biol Chem. April 29, 2005; 280 (17): 16685-94.
Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification. , Pegan S., Nat Neurosci. March 1, 2005; 8 (3): 279-87.