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Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome KCNQ1 Variants. , Rinné S., Int J Mol Sci. January 10, 2023; 24 (2):
Virus-Host Interactions of Enteroviruses and Parvovirus B19 in Myocarditis. , Ho HT., Cell Physiol Biochem. November 18, 2021; 55 (6): 679-703.
4,4'-Diisothiocyanato-2,2'-Stilbenedisulfonic Acid (DIDS) Modulates the Activity of KCNQ1/KCNE1 Channels by an Interaction with the Central Pore Region. , Bollmann E., Cell Physiol Biochem. April 8, 2020; 54 (2): 321-332.
Polyunsaturated fatty acid analogues differentially affect cardiac NaV, CaV, and KV channels through unique mechanisms. , Bohannon BM., Elife. March 24, 2020; 9
Nocturnal Atrial Fibrillation Caused by Mutation in KCND2, Encoding Pore-Forming (α) Subunit of the Cardiac Kv4.2 Potassium Channel. , Drabkin M., Circ Genom Precis Med. November 1, 2018; 11 (11): e002293.
KCNE1 tunes the sensitivity of KV7.1 to polyunsaturated fatty acids by moving turret residues close to the binding site. , Larsson JE., Elife. July 17, 2018; 7
Direct neurotransmitter activation of voltage-gated potassium channels. , Manville RW., Nat Commun. May 10, 2018; 9 (1): 1847.
Insulin treatment augments KCNQ1/ KCNE1 currents but not KCNQ1 currents, which is associated with an increase in KCNE1 expression. , Wu M., Biochem Biophys Res Commun. November 4, 2017; 493 (1): 409-415.
Pro-arrhythmogenic Effects of the V141M KCNQ1 Mutation in Short QT Syndrome and Its Potential Therapeutic Targets: Insights from Modeling. , Lee HC , Lee HC ., J Med Biol Eng. October 1, 2017; 37 (5): 780-789.
Molecular cloning and functional expression of the K + channel K V 7.1 and the regulatory subunit KCNE1 from equine myocardium. , Pedersen PJ., Res Vet Sci. August 1, 2017; 113 79-86.
KCNE1 induces fenestration in the Kv7.1/ KCNE1 channel complex that allows for highly specific pharmacological targeting. , Wrobel E., Nat Commun. October 12, 2016; 7 12795.
The residue I257 at S4-S5 linker in KCNQ1 determines KCNQ1/ KCNE1 channel sensitivity to 1-alkanols. , Xie C., Acta Pharmacol Sin. January 1, 2016; 37 (1): 124-33.
Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel. , Liin SI., Proc Natl Acad Sci U S A. May 5, 2015; 112 (18): 5714-9.
High incidence of functional ion-channel abnormalities in a consecutive Long QT cohort with novel missense genetic variants of unknown significance. , Steffensen AB., Sci Rep. January 12, 2015; 5 10009.
Regulation of Voltage Gated K+ Channel KCNE1/ KCNQ1 by the Janus Kinase JAK3. , Warsi J., Cell Physiol Biochem. January 1, 2015; 37 (6): 2476-85.
Ginseng gintonin activates the human cardiac delayed rectifier K+ channel: involvement of Ca2+/calmodulin binding sites. , Choi SH., Mol Cells. September 1, 2014; 37 (9): 656-63.
Functional assembly of Kv7.1/ Kv7.5 channels with emerging properties on vascular muscle physiology. , Oliveras A., Arterioscler Thromb Vasc Biol. July 1, 2014; 34 (7): 1522-30.
Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channel. , Zaydman MA., Elife. March 12, 2014; 3 e03606.
Upregulation of KCNQ1/ KCNE1 K+ channels by Klotho. , Almilaji A., Channels (Austin). January 1, 2014; 8 (3): 222-9.
Intracellular ATP binding is required to activate the slowly activating K+ channel I(Ks). , Li Y., Proc Natl Acad Sci U S A. November 19, 2013; 110 (47): 18922-7.
Role of the Rap2/ TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling. , Park DS., Biochem Biophys Res Commun. June 28, 2013; 436 (2): 338-43.
Impaired ion channel function related to a common KCNQ1 mutation - implications for risk stratification in long QT syndrome 1. , Aidery P., Gene. December 10, 2012; 511 (1): 26-33.
AMP-activated protein kinase in BK-channel regulation and protection against hearing loss following acoustic overstimulation. , Föller M., FASEB J. October 1, 2012; 26 (10): 4243-53.
Inhibition of cardiac Kir2.1-2.3 channels by beta3 adrenoreceptor antagonist SR 59230A. , Kulzer M., Biochem Biophys Res Commun. July 27, 2012; 424 (2): 315-20.
Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation. , Daulat AM., Mol Cell Biol. January 1, 2012; 32 (1): 173-85.
Regulation of KCNQ1/ KCNE1 by β-catenin. , Wilmes J., Mol Membr Biol. January 1, 2012; 29 (3-4): 87-94.
Involvement of the eukaryotic initiation factor 6 and kermit2/ gipc2 in Xenopus laevis pronephros formation. , Tussellino M., Int J Dev Biol. January 1, 2012; 56 (5): 357-62.
Agonistic and antagonistic roles for TNIK and MINK in non-canonical and canonical Wnt signalling. , Mikryukov A., PLoS One. January 1, 2012; 7 (9): e43330.
KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue. , Nakajo K., J Gen Physiol. November 1, 2011; 138 (5): 521-35.
Extracellular potassium inhibits Kv7.1 potassium channels by stabilizing an inactivated state. , Larsen AP., Biophys J. August 17, 2011; 101 (4): 818-27.
Biophysical properties of mutant KCNQ1 S277L channels linked to hereditary long QT syndrome with phenotypic variability. , Aidery P., Biochim Biophys Acta. April 1, 2011; 1812 (4): 488-94.
Inhibition of the heterotetrameric K+ channel KCNQ1/ KCNE1 by the AMP-activated protein kinase. , Alesutan I., Mol Membr Biol. February 1, 2011; 28 (2): 79-89.
Transmembrane potential of GlyCl-expressing instructor cells induces a neoplastic-like conversion of melanocytes via a serotonergic pathway. , Blackiston D ., Dis Model Mech. January 1, 2011; 4 (1): 67-85.
Ginsenoside Rg3 activates human KCNQ1 K+ channel currents through interacting with the K318 and V319 residues: a role of KCNE1 subunit. , Choi SH., Eur J Pharmacol. July 10, 2010; 637 (1-3): 138-47.
A shared mechanism for lipid- and beta-subunit-coordinated stabilization of the activated K+ channel voltage sensor. , Choi E., FASEB J. May 1, 2010; 24 (5): 1518-24.
Functional delivery of a membrane protein into oocyte membranes using bicelles. , Kang C., Biochemistry. February 2, 2010; 49 (4): 653-5.
KCNQ1/ KCNE1 assembly, co-translation not required. , Vanoye CG., Channels (Austin). January 1, 2010; 4 (2): 108-14.
KCNE1 and KCNE3 beta-subunits regulate membrane surface expression of Kv12.2 K(+) channels in vitro and form a tripartite complex in vivo. , Clancy SM., PLoS One. July 22, 2009; 4 (7): e6330.
The G314S KCNQ1 mutation exerts a dominant-negative effect on expression of KCNQ1 channels in oocytes. , Li W ., Biochem Biophys Res Commun. May 29, 2009; 383 (2): 206-9.
PKC activation and PIP(2) depletion underlie biphasic regulation of IKs by Gq-coupled receptors. , Matavel A., J Mol Cell Cardiol. May 1, 2009; 46 (5): 704-12.
Modulation of potassium channel function confers a hyperproliferative invasive phenotype on embryonic stem cells. , Morokuma J., Proc Natl Acad Sci U S A. October 28, 2008; 105 (43): 16608-13.
KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains. , Xu X., J Gen Physiol. June 1, 2008; 131 (6): 589-603.
Chlorthalidone inhibits the KvLQT1 potassium current in guinea-pig ventricular myocytes and oocytes from Xenopus laevis. , Mancilla-Simbro C., Br J Pharmacol. February 1, 2008; 153 (3): 448-58.
KCNE peptides differently affect voltage sensor equilibrium and equilibration rates in KCNQ1 K+ channels. , Rocheleau JM., J Gen Physiol. January 1, 2008; 131 (1): 59-68.
KCNQ1 and KCNE1 K+ channel components are involved in early left- right patterning in Xenopus laevis embryos. , Morokuma J., Cell Physiol Biochem. January 1, 2008; 21 (5-6): 357-72.
The KCNE1 beta-subunit exerts a transient effect on the KCNQ1 K+ channel. , Poulsen AN., Biochem Biophys Res Commun. November 9, 2007; 363 (1): 133-9.
KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channel. , Nakajo K., J Gen Physiol. September 1, 2007; 130 (3): 269-81.
XRab40 and XCullin5 form a ubiquitin ligase complex essential for the noncanonical Wnt pathway. , Lee RH., EMBO J. August 8, 2007; 26 (15): 3592-606.
Upregulation of KCNE1 induces QT interval prolongation in patients with chronic heart failure. , Watanabe E., Circ J. April 1, 2007; 71 (4): 471-8.
Regulation of endocytic recycling of KCNQ1/ KCNE1 potassium channels. , Seebohm G ., Circ Res. March 16, 2007; 100 (5): 686-92.