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GATA-4 is a novel transcription factor expressed in endocardium of the developing heart. , Kelley C ., Development. July 1, 1993; 118 (3): 817-27.
The Xenopus GATA-4/5/6 genes are associated with cardiac specification and can regulate cardiac-specific transcription during embryogenesis. , Jiang Y., Dev Biol. March 15, 1996; 174 (2): 258-70.
GATA-4 activates transcription via two novel domains that are conserved within the GATA-4/5/6 subfamily. , Morrisey EE., J Biol Chem. March 28, 1997; 272 (13): 8515-24.
The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors. , Durocher D., EMBO J. September 15, 1997; 16 (18): 5687-96.
Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer. , Lien CL., Development. January 1, 1999; 126 (1): 75-84.
GATA transcription factors and cardiac development. , Charron F., Semin Cell Dev Biol. February 1, 1999; 10 (1): 85-91.
Retinoid signaling required for normal heart development regulates GATA-4 in a pathway distinct from cardiomyocyte differentiation. , Kostetskii I., Dev Biol. February 15, 1999; 206 (2): 206-18.
Characterization of the murine A1 adenosine receptor promoter, potent regulation by GATA-4 and Nkx2.5. , Rivkees SA., J Biol Chem. May 14, 1999; 274 (20): 14204-9.
Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/ Nkx-2.5 and GATA-4. , Monzen K., Mol Cell Biol. October 1, 1999; 19 (10): 7096-105.
A role for GATA-4/5/6 in the regulation of Nkx2.5 expression with implications for patterning of the precardiac field. , Jiang Y., Dev Biol. December 1, 1999; 216 (1): 57-71.
Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 ( fgf8/acerebellar). , Reifers F., Development. January 1, 2000; 127 (2): 225-35.
Direct activation of a GATA6 cardiac enhancer by Nkx2.5: evidence for a reinforcing regulatory network of Nkx2.5 and GATA transcription factors in the developing heart. , Molkentin JD., Dev Biol. January 15, 2000; 217 (2): 301-9.
A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2. , Svensson EC., Nat Genet. July 1, 2000; 25 (3): 353-6.
Ventricular expression of tbx5 inhibits normal heart chamber development. , Liberatore CM., Dev Biol. July 1, 2000; 223 (1): 169-80.
Serrate and Notch specify cell fates in the heart field by suppressing cardiomyogenesis. , Rones MS., Development. September 1, 2000; 127 (17): 3865-76.
A role for GATA5 in Xenopus endoderm specification. , Weber H., Development. October 1, 2000; 127 (20): 4345-60.
Maternal VegT is the initiator of a molecular network specifying endoderm in Xenopus laevis. , Xanthos JB., Development. January 1, 2001; 128 (2): 167-80.
The pitx2 homeobox protein is required early for endoderm formation and nodal signaling. . , Faucourt M., Dev Biol. January 15, 2001; 229 (2): 287-306.
Bone morphogenetic protein function is required for terminal differentiation of the heart but not for early expression of cardiac marker genes. , Walters MJ., Mech Dev. February 1, 2001; 100 (2): 263-73.
Inhibition of Wnt activity induces heart formation from posterior mesoderm. , Marvin MJ., Genes Dev. February 1, 2001; 15 (3): 316-27.
Purkinje fibers of the avian heart express a myogenic transcription factor program distinct from cardiac and skeletal muscle. , Takebayashi-Suzuki K., Dev Biol. June 15, 2001; 234 (2): 390-401.
The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development. , Reissmann E., Genes Dev. August 1, 2001; 15 (15): 2010-22.
Microarray-based analysis of early development in Xenopus laevis. , Altmann CR ., Dev Biol. August 1, 2001; 236 (1): 64-75.
Molecular regulation of vertebrate early endoderm development. , Shivdasani RA ., Dev Biol. September 15, 2002; 249 (2): 191-203.
Beating is necessary for transdifferentiation of skeletal muscle-derived cells into cardiomyocytes. , Iijima Y., FASEB J. July 1, 2003; 17 (10): 1361-3.
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5. , Garg V., Nature. July 24, 2003; 424 (6947): 443-7.
Induction of cardiomyocytes by GATA4 in Xenopus ectodermal explants. , Latinkić BV., Development. August 1, 2003; 130 (16): 3865-76.
Transgenic analysis of the atrialnatriuretic factor ( ANF) promoter: Nkx2-5 and GATA-4 binding sites are required for atrial specific expression of ANF. , Small EM ., Dev Biol. September 1, 2003; 261 (1): 116-31.
Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart. , Stennard FA ., Dev Biol. October 15, 2003; 262 (2): 206-24.
Transcriptional regulation of the cardiac-specific MLC2 gene during Xenopus embryonic development. , Latinkic BV ., Development. February 1, 2004; 131 (3): 669-79.
Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes. , Sinner D ., Development. July 1, 2004; 131 (13): 3069-80.
GATA4, 5 and 6 mediate TGFbeta maintenance of endodermal gene expression in Xenopus embryos. , Afouda BA ., Development. February 1, 2005; 132 (4): 763-74.
Global analysis of RAR-responsive genes in the Xenopus neurula using cDNA microarrays. , Arima K., Dev Dyn. February 1, 2005; 232 (2): 414-31.
An atlas of differential gene expression during early Xenopus embryogenesis. , Pollet N ., Mech Dev. March 1, 2005; 122 (3): 365-439.
Identification of novel genes affecting mesoderm formation and morphogenesis through an enhanced large scale functional screen in Xenopus. , Chen JA ., Mech Dev. March 1, 2005; 122 (3): 307-31.
Myocardin is sufficient and necessary for cardiac gene expression in Xenopus. , Small EM ., Development. March 1, 2005; 132 (5): 987-97.
GATA factors as key regulatory molecules in the development of Drosophila endoderm. , Murakami R., Dev Growth Differ. December 1, 2005; 47 (9): 581-9.
Global analysis of the transcriptional network controlling Xenopus endoderm formation. , Sinner D ., Development. May 1, 2006; 133 (10): 1955-66.
A role for GATA factors in Xenopus gastrulation movements. , Fletcher G., Mech Dev. October 1, 2006; 123 (10): 730-45.
The KLF family of transcriptional regulators in cardiomyocyte proliferation and differentiation. , Nemer M., Cell Cycle. January 15, 2007; 6 (2): 117-21.
Left-sided embryonic expression of the BCL-6 corepressor, BCOR, is required for vertebrate laterality determination. , Hilton EN ., Hum Mol Genet. July 15, 2007; 16 (14): 1773-82.
Tsukushi modulates Xnr2, FGF and BMP signaling: regulation of Xenopus germ layer formation. , Morris SA., PLoS One. October 10, 2007; 2 (10): e1004.
Redundancy and evolution of GATA factor requirements in development of the myocardium. , Peterkin T., Dev Biol. November 15, 2007; 311 (2): 623-35.
Identification of novel ciliogenesis factors using a new in vivo model for mucociliary epithelial development. , Hayes JM., Dev Biol. December 1, 2007; 312 (1): 115-30.
Lessons from the lily pad: Using Xenopus to understand heart disease. , Bartlett HL., Drug Discov Today Dis Models. January 1, 2008; 5 (3): 141-146.
The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm. , Spagnoli FM ., Development. February 1, 2008; 135 (3): 451-61.
Vertebrate CASTOR is required for differentiation of cardiac precursor cells at the ventral midline. , Christine KS ., Dev Cell. April 1, 2008; 14 (4): 616-23.
HIF-1alpha signaling upstream of NKX2.5 is required for cardiac development in Xenopus. , Nagao K., J Biol Chem. April 25, 2008; 283 (17): 11841-9.
A crucial role of a high mobility group protein HMGA2 in cardiogenesis. , Monzen K., Nat Cell Biol. May 1, 2008; 10 (5): 567-74.
XHAPLN3 plays a key role in cardiogenesis by maintaining the hyaluronan matrix around heart anlage. , Ito Y ., Dev Biol. July 1, 2008; 319 (1): 34-45.