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TopBP1 utilises a bipartite GINS binding mode to support genome replication. , Day M., Nat Commun. February 27, 2024; 15 (1): 1797.
Rif1 restrains the rate of replication origin firing in Xenopus laevis. , Haccard O ., Commun Biol. July 29, 2023; 6 (1): 788.
The p97 segregase cofactor Ubxn7 facilitates replisome disassembly during S-phase. , Tarcan Z., J Biol Chem. August 1, 2022; 298 (8): 102234.
Polo-like kinase 1 (Plk1) regulates DNA replication origin firing and interacts with Rif1 in Xenopus. , Ciardo D., Nucleic Acids Res. September 27, 2021; 49 (17): 9851-9869.
Mitotic replisome disassembly depends on TRAIP ubiquitin ligase activity. , Priego Moreno S., Life Sci Alliance. April 12, 2019; 2 (2):
RPA-coated single-stranded DNA promotes the ETAA1-dependent activation of ATR. , Lyu K., Cell Cycle. April 1, 2019; 18 (8): 898-913.
Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements. , Deng L., Mol Cell. March 7, 2019; 73 (5): 915-929.e6.
Mitotic entry drives replisome disassembly at stalled replication forks. , Hashimoto Y., Biochem Biophys Res Commun. November 17, 2018; 506 (1): 108-113.
MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication. , Kumagai A ., Mol Biol Cell. November 1, 2017; 28 (22): 2998-3012.
Reversal of DDK-Mediated MCM Phosphorylation by Rif1- PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/ Chk1. , Alver RC., Cell Rep. March 7, 2017; 18 (10): 2508-2520.
Xenopus Mcm10 is a CDK-substrate required for replication fork stability. , Chadha GS., Cell Cycle. August 17, 2016; 15 (16): 2183-2195.
Structure of human Cdc45 and implications for CMG helicase function. , Simon AC., Nat Commun. May 18, 2016; 7 11638.
The mechanism of DNA replication termination in vertebrates. , Dewar JM ., Nature. September 17, 2015; 525 (7569): 345-50.
Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1. , Poh WT., Open Biol. January 8, 2014; 4 (1): 130138.
Mta2 promotes Tipin-dependent maintenance of replication fork integrity. , Errico A., Cell Cycle. January 1, 2014; 13 (13): 2120-8.
Depletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts. , Taylor EM., Nucleic Acids Res. September 1, 2013; 41 (16): 7725-37.
DNA topoisomerase IIα controls replication origin cluster licensing and firing time in Xenopus egg extracts. , Gaggioli V., Nucleic Acids Res. August 1, 2013; 41 (15): 7313-31.
The Mre11- Rad50- Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks. , Lee J ., Mol Biol Cell. May 1, 2013; 24 (9): 1343-53.
RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks. , Hashimoto Y., Nat Struct Mol Biol. December 4, 2011; 19 (1): 17-24.
Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication. , Kumagai A ., J Cell Biol. June 13, 2011; 193 (6): 995-1007.
Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex. , Kundu LR., Nucleic Acids Res. September 1, 2010; 38 (16): 5409-18.
GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication. , Balestrini A., Nat Cell Biol. May 1, 2010; 12 (5): 484-91.
Treslin collaborates with TopBP1 in triggering the initiation of DNA replication. , Kumagai A ., Cell. February 5, 2010; 140 (3): 349-59.
Tipin/ Tim1/ And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion. , Errico A., EMBO J. December 2, 2009; 28 (23): 3681-92.
Plx1 is required for chromosomal DNA replication under stressful conditions. , Trenz K., EMBO J. March 19, 2008; 27 (6): 876-85.
The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication. , Matsuno K., Mol Cell Biol. July 1, 2006; 26 (13): 4843-52.
Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress. , Woodward AM., J Cell Biol. June 5, 2006; 173 (5): 673-83.
The DNA polymerase activity of Pol epsilon holoenzyme is required for rapid and efficient chromosomal DNA replication in Xenopus egg extracts. , Shikata K., BMC Biochem. May 1, 2006; 7 21.
The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation. , Oehlmann M., J Cell Biol. April 26, 2004; 165 (2): 181-90.
DNA damage-induced replication arrest in Xenopus egg extracts. , Stokes MP., J Cell Biol. October 27, 2003; 163 (2): 245-55.
The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication. , Van Hatten RA., J Cell Biol. November 25, 2002; 159 (4): 541-7.