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TopBP1 utilises a bipartite GINS binding mode to support genome replication. , Day M., Nat Commun. February 27, 2024; 15 (1): 1797.
Polo-like kinase 1 (Plk1) regulates DNA replication origin firing and interacts with Rif1 in Xenopus. , Ciardo D., Nucleic Acids Res. September 27, 2021; 49 (17): 9851-9869.
RPA-coated single-stranded DNA promotes the ETAA1-dependent activation of ATR. , Lyu K., Cell Cycle. April 1, 2019; 18 (8): 898-913.
APE2 promotes DNA damage response pathway from a single-strand break. , Lin Y., Nucleic Acids Res. March 16, 2018; 46 (5): 2479-2494.
MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication. , Kumagai A ., Mol Biol Cell. November 1, 2017; 28 (22): 2998-3012.
Xenopus Mcm10 is a CDK-substrate required for replication fork stability. , Chadha GS., Cell Cycle. August 17, 2016; 15 (16): 2183-2195.
The Mre11- Rad50- Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks. , Lee J ., Mol Biol Cell. May 1, 2013; 24 (9): 1343-53.
Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication. , Kumagai A ., J Cell Biol. June 13, 2011; 193 (6): 995-1007.
GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication. , Balestrini A., Nat Cell Biol. May 1, 2010; 12 (5): 484-91.
Continued primer synthesis at stalled replication forks contributes to checkpoint activation. , Van C., J Cell Biol. April 19, 2010; 189 (2): 233-46.
Rad17 plays a central role in establishment of the interaction between TopBP1 and the Rad9- Hus1- Rad1 complex at stalled replication forks. , Lee J , Lee J ., Mol Biol Cell. March 15, 2010; 21 (6): 926-35.
Treslin collaborates with TopBP1 in triggering the initiation of DNA replication. , Kumagai A ., Cell. February 5, 2010; 140 (3): 349-59.
Tipin/ Tim1/ And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion. , Errico A., EMBO J. December 2, 2009; 28 (23): 3681-92.
TopBP1 and DNA polymerase-alpha directly recruit the 9-1-1 complex to stalled DNA replication forks. , Yan S ., J Cell Biol. March 23, 2009; 184 (6): 793-804.
The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication. , Matsuno K., Mol Cell Biol. July 1, 2006; 26 (13): 4843-52.
The DNA polymerase activity of Pol epsilon holoenzyme is required for rapid and efficient chromosomal DNA replication in Xenopus egg extracts. , Shikata K., BMC Biochem. May 1, 2006; 7 21.
Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling. , Yan S ., J Cell Biol. April 24, 2006; 173 (2): 181-6.
The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication. , Van Hatten RA., J Cell Biol. November 25, 2002; 159 (4): 541-7.