Papers associated with anatomical cluster (and kcnh2)

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	Molecular Determinants for the High-Affinity Blockade of Human Ether-à-go-go-Related Gene K + Channel by Tolterodine., Wang N., J Cardiovasc Pharmacol. November 1, 2022; 80 (5): 679-689.
	Bioelectric signaling: Reprogrammable circuits underlying embryogenesis, regeneration, and cancer., Levin M., Cell. April 15, 2021;
	The hERG channel activator, RPR260243, enhances protective IKr current early in the refractory period reducing arrhythmogenicity in zebrafish hearts., Shi YP., Am J Physiol Heart Circ Physiol. August 1, 2020; 319 (2): H251-H261.
	Investigating the utility of adult zebrafish ex vivo whole hearts to pharmacologically screen hERG channel activator compounds., Hull CM., Am J Physiol Regul Integr Comp Physiol. December 1, 2019; 317 (6): R921-R931.
	The acute effects of hydrocortisone on cardiac electrocardiography, action potentials, intracellular calcium, and contraction: The role of protein kinase C., Park MH., Mol Cell Endocrinol. August 20, 2019; 494 110488.
	Importance of the Choice of a Recombinant System to Produce Large Amounts of Functional Membrane Protein hERG., Vasseur L., Int J Mol Sci. June 28, 2019; 20 (13):
	Fluorescent analogues of BeKm-1 with high and specific activity against the hERG channel., Vasseur L., Toxicon X. February 23, 2019; 2 100010.
	Facilitation of IKr current by some hERG channel blockers suppresses early afterdepolarizations., Furutani K., J Gen Physiol. February 4, 2019; 151 (2): 214-230.
	Inhibition of inwardly rectifying Kir2.x channels by the novel anti-cancer agent gambogic acid depends on both pore block and PIP2 interference., Scherer D., Naunyn Schmiedebergs Arch Pharmacol. July 1, 2017; 390 (7): 701-710.
	hERG Channel Inhibitory Daphnane Diterpenoid Orthoesters and Polycephalones A and B with Unprecedented Skeletons from Gnidia polycephala., De Mieri M., J Nat Prod. July 24, 2015; 78 (7): 1697-707.
	Eag Domains Regulate LQT Mutant hERG Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes., Liu QN., PLoS One. April 22, 2015; 10 (4): e0123951.
	Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels., Ng CA., J Biol Chem. September 12, 2014; 289 (37): 25822-32.
	The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT., Mechakra A., Gene. February 25, 2014; 536 (2): 348-56.
	Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels., Perry MD., J Gen Physiol. September 1, 2013; 142 (3): 275-88.
	Blocking of the human ether-à-go-go-related gene channel by imatinib mesylate., Dong Q., Biol Pharm Bull. January 1, 2013; 36 (2): 268-75.
	Kcnh1 voltage-gated potassium channels are essential for early zebrafish development., Stengel R., J Biol Chem. October 12, 2012; 287 (42): 35565-35575.
	Marine algal toxin azaspiracid is an open-state blocker of hERG potassium channels., Twiner MJ., Chem Res Toxicol. September 17, 2012; 25 (9): 1975-84.
	Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway., Ferrer T., J Biol Chem. November 11, 2011; 286 (45): 39091-9.
	Sig1R protein regulates hERG channel expression through a post-translational mechanism in leukemic cells., Crottès D., J Biol Chem. August 12, 2011; 286 (32): 27947-58.
	hERGAPDbase: a database documenting hERG channel inhibitory potentials and APD-prolongation activities of chemical compounds., Hishigaki H., Database (Oxford). May 17, 2011; 2011 bar017.
	Recombinant expression of the toxic peptide ErgTx1 and role of Met35 on its stability and function., Jimenez-Vargas JM., Peptides. March 1, 2011; 32 (3): 560-7.
	hERG K+ channel-associated cardiac effects of the antidepressant drug desipramine., Staudacher I., Naunyn Schmiedebergs Arch Pharmacol. February 1, 2011; 383 (2): 119-39.
	Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels., Larsen AP., Br J Pharmacol. October 1, 2010; 161 (3): 614-28.
	Modification of hERG1 channel gating by Cd2+., Abbruzzese J., J Gen Physiol. August 1, 2010; 136 (2): 203-24.
	Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine., Obers S., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2010; 381 (5): 385-400.
	The amiodarone derivative KB130015 activates hERG1 potassium channels via a novel mechanism., Gessner G., Eur J Pharmacol. April 25, 2010; 632 (1-3): 52-9.
	Modulation of human ether a gogo related channels by CASQ2 contributes to etiology of catecholaminergic polymorphic ventricular tachycardia (CPVT)., Eckey K., Cell Physiol Biochem. January 1, 2010; 26 (4-5): 503-12.
	Extracellular potassium dependency of block of HERG by quinidine and cisapride is primarily determined by the permeant ion and not by inactivation., Barrows B., Channels (Austin). January 1, 2009; 3 (4): 239-48.
	Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current., Larsen AP., Pflugers Arch. September 1, 2008; 456 (6): 1137-48.
	Topological mapping of the asymmetric drug binding to the human ether-à-go-go-related gene product (HERG) potassium channel by use of tandem dimers., Myokai T., Mol Pharmacol. June 1, 2008; 73 (6): 1643-51.
	Probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243)., Xu X., Mol Pharmacol. June 1, 2008; 73 (6): 1709-21.
	Extracellular acidification and hyperkalemia induce changes in HERG inhibition by ibutilide., Lin C., Cardiology. January 1, 2008; 110 (3): 209-16.
	Cooperative interactions between R531 and acidic residues in the voltage sensing module of hERG1 channels., Piper DR., Cell Physiol Biochem. January 1, 2008; 21 (1-3): 37-46.
	Zebrafish model for human long QT syndrome., Arnaout R., Proc Natl Acad Sci U S A. July 3, 2007; 104 (27): 11316-21.
	Probing the outer mouth structure of the HERG channel with peptide toxin footprinting and molecular modeling., Tseng GN., Biophys J. May 15, 2007; 92 (10): 3524-40.
	Upregulation of KCNE1 induces QT interval prolongation in patients with chronic heart failure., Watanabe E., Circ J. April 1, 2007; 71 (4): 471-8.
	The effects of quinidine and its chiral isolates on erg-1sm potassium current and correlation with gastrointestinal augmentation., Cvetanovic I., Am J Ther. January 1, 2007; 14 (3): 269-76.
	[Electrophysiological characterization of long QT syndrome associated mutations V630A and N633S]., She HR., Zhonghua Xin Xue Guan Bing Za Zhi. June 1, 2006; 34 (6): 523-7.
	Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels., Clarke CE., J Physiol. June 1, 2006; 573 (Pt 2): 291-304.
	Expression and functional characterization of the human ether-à-go-go-related gene (HERG) K+ channel cardiac splice variant in Xenopus laevis oocytes., Aydar E., J Membr Biol. January 1, 2006; 211 (2): 115-26.
	In vivo targeting of ERG potassium channels in mice and dogs by a positron-emitting analogue of fluoroclofilium., Kim SW., Exp Mol Med. August 31, 2005; 37 (4): 269-75.
	Effect of beta-adrenoceptor blockers on human ether-a-go-go-related gene (HERG) potassium channels., Dupuis DS., Basic Clin Pharmacol Toxicol. February 1, 2005; 96 (2): 123-30.
	Structure-function studies of the outer mouth and voltage sensor domain of hERG., Tseng GN., Novartis Found Symp. January 1, 2005; 266 19-35; discussion 35-45.
	Block of wild-type and inactivation-deficient human ether-a-go-go-related gene K+ channels by halofantrine., Sánchez-Chapula JA., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 484-91.
	Gating charges in the activation and inactivation processes of the HERG channel., Zhang M., J Gen Physiol. December 1, 2004; 124 (6): 703-18.
	Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by alpha(1A)-adrenoceptors., Thomas D., J Mol Med (Berl). December 1, 2004; 82 (12): 826-37.
	Identification and characterisation of a novel KCNQ1 mutation in a family with Romano-Ward syndrome., Zehelein J., Biochim Biophys Acta. November 5, 2004; 1690 (3): 185-92.
	Molecular basis of slow activation of the human ether-a-go-go related gene potassium channel., Subbiah RN., J Physiol. July 15, 2004; 558 (Pt 2): 417-31.
	Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin., Thomas D., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2004; 369 (5): 462-72.
	Physicochemical features of the HERG channel drug binding site., Fernandez D., J Biol Chem. March 12, 2004; 279 (11): 10120-7.

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