Xenbase Image ID: 149271

Figure 4. mZIP impairs maintenance of retinotectal synapses in vivo. A, Representative immunostaining of the tectal neuropil from a horizontal brain section with antibodies against SNAP-25 (red) and PSD-95 (green) 4 h after tectal infusion of vehicle (control) and mZIP. Yellow puncta represent the overlap of SNAP-25 and PSD-95 puncta. Scale bars, 1 μm. B, C, Quantitative analysis of the density of SNAP-25 puncta, PSD-95 puncta, and juxtaposed puncta (B), as well as colocalization probability (C), normalized by the average value of the corresponding controls (n = 5 tadpoles for each condition; *p < 0.05). Image published in: Liu XF et al. (2009) Copyright © 2009. This image is reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue snap25.L ric-4, ric4, sec9, snap-25 X. laevis Throughout NF stage 47 brain optic tectum neuropil of the optic tectum dlg4.L LOC108703559, LOC108711809, psd-95, psd95, sap-90, sap90 X. laevis Throughout NF stage 47 brain optic tectum neuropil of the optic tectum Image source: Published Larger Image Printer Friendly View

Return to previous page