Xenbase Image ID: 79711

Fig. 2. Localization of InsR transcripts during embryogenesis by whole mount in situ hybridization. (A±G) Expression of InsR mRNA at different stages of embryogenesis (A, stage 61/2; B, stage 9; C, stage 101/2; D, stages 13 (left) and 17 (right); E, stages 23 (left) and 25 (right); F, stage 32; G, stage 37). Control: embryos in the top row of each picture are hybridized with InsR sense probe. Four different views are presented in pictures (A±C): animal (A) or vegetative (V) hemisphere, lateral view (l) or parasagittal section. InsR expression in the anterior part (E) of a stage 37 embryo observed at higher magni®cation. Transverse sections (stage 37) through the encephalon (I, proencephalon; J and K, rhombencephalon), the eye (L: oc, optic cup; l, lens), the otic vesicle (ov, picture M), the pronephros (pn, picture N) and the somites (picture O) readily show that InsR is expressed in these tissues. Image published in: Groigno L et al. (1999) Copyright © 1999. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue insr.L cd220, hhf5, insulin receptor, Xe-InsR, XTK1, XTK1a, XTK1b X. laevis Sometime during NF stage 6.5 to NF stage 9 animal cap animal insr.L cd220, hhf5, insulin receptor, Xe-InsR, XTK1, XTK1a, XTK1b X. laevis Throughout NF stage 10.5 animal animal cap insr.L cd220, hhf5, insulin receptor, Xe-InsR, XTK1, XTK1a, XTK1b X. laevis Throughout NF stage 13 dorsal ectoderm neuroectoderm insr.L cd220, hhf5, insulin receptor, Xe-InsR, XTK1, XTK1a, XTK1b X. laevis Throughout NF stage 23 to NF stage 25 head region insr.L cd220, hhf5, insulin receptor, Xe-InsR, XTK1, XTK1a, XTK1b X. laevis Throughout NF stage 32 somite head mesoderm otic vesicle insr.L cd220, hhf5, insulin receptor, Xe-InsR, XTK1, XTK1a, XTK1b X. laevis Throughout NF stage 37 and 38 somite pronephric kidney pronephric nephron late proximal tubule early distal tubule early proximal tubule pharyngeal arch otic vesicle head region neural tube brain forebrain hindbrain eye retina Image source: Published Larger Image Printer Friendly View

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