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Summary Expression Phenotypes Gene Literature (398) GO Terms (14) Nucleotides (229) Proteins (58) Interactants (1740) Wiki
XB-GENEPAGE-479317
???displayGene.symbol???:
 notch1

???displayGene.name???: 
notch 1 receptor

???displayGene.synonyms???
notch , notch-1 , x-notch-1 , xnotch , xnotch1 , xotch [+] ( Nomenclature history )

???displayGene.geneFunction???
signal transduction, receptor for delta class ligands

Protein Function :
Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellul...[+]


InterPro :
p53 DNA-bd, p53/RUNT-type TF DNA-bd sf, p53 tetramer sf, Tp73, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Adams-Oliver syndrome [+]

External Links:
GEO Series :
GSE76342.
1/5
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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