Summary Literature (785)

Xenbase Articles :
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Subthreshold changes of voltage-dependent activation of the K(V)7.2 channel in neonatal epilepsy., Hunter J,Maljevic S,Shankar A,Siegel A,Weissman B,Holt P,Olson L,Lerche H,Escayg A, Neurobiol Dis. October 1, 2006; 24(1):1095-953X.

The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion., Pacheco-Alvarez D,Cristóbal PS,Meade P,Moreno E,Vazquez N,Muñoz E,Díaz A,Juárez ME,Giménez I,Gamba G, J Biol Chem. September 29, 2006; 281(39):1083-351X.

Characterization of atrazine-induced gonadal malformations in African clawed frogs (Xenopus laevis) and comparisons with effects of an androgen antagonist (cyproterone acetate) and exogenous estrogen (17beta-estradiol): Support for the demasculinization/feminization hypothesis., Hayes TB,Stuart AA,Mendoza M,Collins A,Noriega N,Vonk A,Johnston G,Liu R,Kpodzo D, Environ Health Perspect. April 1, 2006; 114 Suppl 1(Suppl 1):0091-6765.

Transforming growth factor beta signaling, vascular remodeling, and hypertension., August P,Suthanthiran M, N Engl J Med. June 22, 2006; 354(25):1533-4406.

Introduction to nucleocytoplasmic transport: molecules and mechanisms., Peters R, Methods Mol Biol. January 1, 2006; 322:1940-6029.

The Wnt-dependent signaling pathways as target in oncology drug discovery., Janssens N,Janicot M,Perera T, Invest New Drugs. July 1, 2006; 24(4):0167-6997.

Coupling modes and stoichiometry of Cl-/HCO3- exchange by slc26a3 and slc26a6., Shcheynikov N,Wang Y,Park M,Ko SB,Dorwart M,Naruse S,Thomas PJ,Muallem S, J Gen Physiol. May 1, 2006; 127(5):1540-7748.

Functional and clinical characterization of a mutation in KCNJ2 associated with Andersen-Tawil syndrome., Lu CW,Lin JH,Rajawat YS,Jerng H,Rami TG,Sanchez X,DeFreitas G,Carabello B,DeMayo F,Kearney DL,Miller G,Li H,Pfaffinger PJ,Bowles NE,Khoury DS,Towbin JA, J Med Genet. August 1, 2006; 43(8):1468-6244.

Emilin1 links TGF-beta maturation to blood pressure homeostasis., Zacchigna L,Vecchione C,Notte A,Cordenonsi M,Dupont S,Maretto S,Cifelli G,Ferrari A,Maffei A,Fabbro C,Braghetta P,Marino G,Selvetella G,Aretini A,Colonnese C,Bettarini U,Russo G,Soligo S,Adorno M,Bonaldo P,Volpin D,Piccolo S,Lembo G,Bressan GM, Cell. March 10, 2006; 124(5):1097-4172.

WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway., de Los Heros P,Kahle KT,Rinehart J,Bobadilla NA,Vázquez N,San Cristobal P,Mount DB,Lifton RP,Hebert SC,Gamba G, Proc Natl Acad Sci U S A. February 7, 2006; 103(6):1091-6490.

Dystroglycan is required for proper retinal layering., Lunardi A,Cremisi F,Dente L, Dev Biol. February 15, 2006; 290(2):1095-564X.

A novel GJA8 mutation is associated with autosomal dominant lamellar pulverulent cataract: further evidence for gap junction dysfunction in human cataract., Arora A,Minogue PJ,Liu X,Reddy MA,Ainsworth JR,Bhattacharya SS,Webster AR,Hunt DM,Ebihara L,Moore AT,Beyer EC,Berthoud VM, J Med Genet. January 1, 2006; 43(1):1468-6244.

Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks., Sobeck A,Stone S,Costanzo V,de Graaf B,Reuter T,de Winter J,Wallisch M,Akkari Y,Olson S,Wang W,Joenje H,Christian JL,Lupardus PJ,Cimprich KA,Gautier J,Hoatlin ME, Mol Cell Biol. January 1, 2006; 26(2):1098-5549.

Barrier-to-autointegration factor phosphorylation on Ser-4 regulates emerin binding to lamin A in vitro and emerin localization in vivo., Bengtsson L,Wilson KL, Mol Biol Cell. March 1, 2006; 17(3):1939-4586.

Dominant-negative effects of human P/Q-type Ca2+ channel mutations associated with episodic ataxia type 2., Jeng CJ,Chen YT,Chen YT,Chen YW,Chen YW,Tang CY, Am J Physiol Cell Physiol. April 1, 2006; 290(4):1522-1563.

A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction., Persson AS,Klement G,Almgren M,Sahlholm K,Nilsson J,Petersson S,Arhem P,Schalling M,Lavebratt C, BMC Neurosci. November 23, 2005; 6:1471-2202.

WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability., Kahle KT,Rinehart J,de Los Heros P,Louvi A,Meade P,Vazquez N,Hebert SC,Gamba G,Gimenez I,Lifton RP, Proc Natl Acad Sci U S A. November 15, 2005; 102(46):1091-6490.

Reduced U snRNP assembly causes motor axon degeneration in an animal model for spinal muscular atrophy., Winkler C,Eggert C,Gradl D,Meister G,Giegerich M,Wedlich D,Laggerbauer B,Fischer U, Genes Dev. October 1, 2005; 19(19):1549-5477.

Neural and eye-specific defects associated with loss of the imitation switch (ISWI) chromatin remodeler in Xenopus laevis., Dirscherl SS,Henry JJ,Krebs JE, Mech Dev. November 1, 2005; 122(11):1872-6356.

ABCA4 mutations causing mislocalization are found frequently in patients with severe retinal dystrophies., Wiszniewski W,Zaremba CM,Yatsenko AN,Jamrich M,Wensel TG,Lewis RA,Lupski JR, Hum Mol Genet. October 1, 2005; 14(19):1460-2083.

A novel TMPRSS3 missense mutation in a DFNB8/10 family prevents proteolytic activation of the protein., Wattenhofer M,Sahin-Calapoglu N,Andreasen D,Kalay E,Caylan R,Braillard B,Fowler-Jaeger N,Reymond A,Rossier BC,Karaguzel A,Antonarakis SE, Hum Genet. October 1, 2005; 117(6):1432-1203.

Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome., Sangrithi MN,Bernal JA,Madine M,Philpott A,Lee J,Lee J,Dunphy WG,Venkitaraman AR, Cell. June 17, 2005; 121(6):1097-4172.

Functional evaluation of Dent's disease-causing mutations: implications for ClC-5 channel trafficking and internalization., Ludwig M,Doroszewicz J,Seyberth HW,Bökenkamp A,Balluch B,Nuutinen M,Utsch B,Waldegger S, Hum Genet. July 1, 2005; 117(2-3):1432-1203.

WNK kinases and the control of blood pressure., Cope G,Golbang A,O'Shaughnessy KM, Pharmacol Ther. May 1, 2005; 106(2):0163-7258.

Mutation of single murine acetylcholine receptor subunits reveals differential contribution of P121 to acetylcholine binding and channel opening., Peter C,Korngreen A,Witzemann V, Pflugers Arch. June 1, 2005; 450(3):1432-2013.

A gating mutation at the internal mouth of the Kir6.2 pore is associated with DEND syndrome., Proks P,Girard C,Haider S,Gloyn AL,Hattersley AT,Sansom MS,Ashcroft FM, EMBO Rep. May 1, 2005; 6(5):1469-3178.

Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations., Splawski I,Timothy KW,Decher N,Kumar P,Sachse FB,Beggs AH,Sanguinetti MC,Keating MT, Proc Natl Acad Sci U S A. June 7, 2005; 102(23):1091-6490.

A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization., Hurst RS,Hajós M,Raggenbass M,Wall TM,Higdon NR,Lawson JA,Rutherford-Root KL,Berkenpas MB,Hoffmann WE,Piotrowski DW,Groppi VE,Allaman G,Ogier R,Bertrand S,Bertrand D,Arneric SP, J Neurosci. April 27, 2005; 25(17):1529-2401.

Application of polyacrylamide gel electrophoresis of fluorophore-labeled saccharides for analysis of hyaluronan and chondroitin sulfate in human and animal tissues and cell cultures., Karousou EG,Viola M,Genasetti A,Vigetti D,Luca GD,Karamanos NK,Passi A, Biomed Chromatogr. December 1, 2005; 19(10):0269-3879.

Severe neuropathy with leaky connexin32 hemichannels., Liang GS,de Miguel M,Gómez-Hernández JM,Glass JD,Scherer SS,Mintz M,Barrio LC,Fischbeck KH, Ann Neurol. May 1, 2005; 57(5):1531-8249.

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways., Simons M,Gloy J,Ganner A,Bullerkotte A,Bashkurov M,Krönig C,Schermer B,Benzing T,Cabello OA,Jenny A,Mlodzik M,Polok B,Driever W,Obara T,Walz G, Nat Genet. May 1, 2005; 37(5):1546-1718.

Polymorphic ventricular tachycardia and KCNJ2 mutations., Chun TU,Epstein MR,Dick M,Andelfinger G,Ballester L,Vanoye CG,George AL,Benson DW, Heart Rhythm. July 1, 2004; 1(2):1547-5271.

Kinetic properties of nuclear transport conferred by the retinoblastoma (Rb) NLS., Hu W,Kemp BE,Jans DA, J Cell Biochem. July 1, 2005; 95(4):0730-2312.

Simple sequence in brain and nervous system specific proteins., Huntley MA,Mahmood S,Golding GB, Genome. April 1, 2005; 48(2):0831-2796.

AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer., Zhang JS,Gong A,Cheville JC,Smith DI,Young CY, Genes Chromosomes Cancer. July 1, 2005; 43(3):1045-2257.

Effect of galantamine on the human alpha7 neuronal nicotinic acetylcholine receptor, the Torpedo nicotinic acetylcholine receptor and spontaneous cholinergic synaptic activity., Texidó L,Ros E,Martín-Satué M,López S,Aleu J,Marsal J,Solsona C, Br J Pharmacol. July 1, 2005; 145(5):1476-5381.

Epithelial-connective tissue cross-talk is essential for regeneration of intestinal epithelium., Ishizuya-Oka A, J Nippon Med Sch. February 1, 2005; 72(1):1345-4676.

Induction of ectopic olfactory structures and bone morphogenetic protein inhibition by Rossy, a group XII secreted phospholipase A2., Muñoz-Sanjuán I,Brivanlou AH, Mol Cell Biol. May 1, 2005; 25(9):1098-5549.

The influence of extracellular acidosis on the effect of IKr blockers., Lin C,Ke X,Cvetanovic I,Ranade V,Somberg J, J Cardiovasc Pharmacol Ther. March 1, 2005; 10(1):1074-2484.

Atrial natriuretic peptide inhibits the actions of FSH and forskolin in meiotic maturation of pig oocytes via different signalling pathways., Zhang M,Tao Y,Zhou B,Xie H,Wang F,Lei L,Huo L,Sun Q,Xia G, J Mol Endocrinol. April 1, 2005; 34(2):1479-6813.

Emerin expression in early development of Xenopus laevis., Gareiss M,Eberhardt K,Krüger E,Kandert S,Böhm C,Zentgraf H,Müller CR,Dabauvalle MC, Eur J Cell Biol. March 1, 2005; 84(2-3):0171-9335.

Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium., Lips KS,Volk C,Schmitt BM,Pfeil U,Arndt P,Miska D,Ermert L,Kummer W,Koepsell H, Am J Respir Cell Mol Biol. July 1, 2005; 33(1):1535-4989.

Anxiolytic effects of Maxipost (BMS-204352) and retigabine via activation of neuronal Kv7 channels., Korsgaard MP,Hartz BP,Brown WD,Ahring PK,Strøbaek D,Mirza NR, J Pharmacol Exp Ther. July 1, 2005; 314(1):1521-0103.

Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos., Tao Q,Tao Q,Yokota C,Puck H,Kofron M,Birsoy B,Yan D,Asashima M,Wylie CC,Lin X,Heasman J, Cell. March 25, 2005; 120(6):1097-4172.

Functional polymorphisms in the human beta4 subunit of nicotinic acetylcholine receptors., Liang Y,Salas R,Marubio L,Bercovich D,De Biasi M,Beaudet AL,Dani JA, Neurogenetics. February 1, 2005; 6(1):1364-6745.

Transgenic animal models of tauopathies., Lee VM,Kenyon TK,Trojanowski JQ, Biochim Biophys Acta. January 3, 2005; 1739(2-3):0006-3002.

The MinK-related peptides., McCrossan ZA,Abbott GW, Neuropharmacology. November 1, 2004; 47(6):1873-7064.

A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity., Hertel J,Struthers H,Horj CB,Hruz PW, J Biol Chem. December 31, 2004; 279(53):1083-351X.

A novel missense mutation in the sodium bicarbonate cotransporter (NBCe1/SLC4A4) causes proximal tubular acidosis and glaucoma through ion transport defects., Dinour D,Chang MH,Satoh J,Smith BL,Smith BL,Angle N,Knecht A,Serban I,Holtzman EJ,Romero MF, J Biol Chem. December 10, 2004; 279(50):1083-351X.

The amino acid transporter asc-1 is not involved in cystinuria., Pineda M,Font M,Bassi MT,Manzoni M,Borsani G,Marigo V,Fernández E,Río RM,Purroy J,Zorzano A,Nunes V,Palacín M, Kidney Int. October 1, 2004; 66(4):1523-1755.

Familial hemiplegic migraine type 1 mutations K1336E, W1684R, and V1696I alter Cav2.1 Ca2+ channel gating: evidence for beta-subunit isoform-specific effects., Müllner C,Broos LA,van den Maagdenberg AM,Striessnig J, J Biol Chem. December 10, 2004; 279(50):1083-351X.

Regulation and function of small heat shock protein genes during amphibian development., Heikkila JJ, J Cell Biochem. November 1, 2004; 93(4):0730-2312.

The Fanconi anemia gene product FANCF is a flexible adaptor protein., Léveillé F,Blom E,Medhurst AL,Bier P,Laghmani el H,Johnson M,Rooimans MA,Sobeck A,Waisfisz Q,Arwert F,Patel KJ,Hoatlin ME,Joenje H,de Winter JP, J Biol Chem. September 17, 2004; 279(38):1083-351X.

Evidence for stabilization of aquaporin-2 folding mutants by N-linked glycosylation in endoplasmic reticulum., Buck TM,Eledge J,Skach WR, Am J Physiol Cell Physiol. November 1, 2004; 287(5):1522-1563.

Uncoupling of photoreceptor peripherin/rds fusogenic activity from biosynthesis, subunit assembly, and targeting: a potential mechanism for pathogenic effects., Ritter LM,Boesze-Battaglia K,Tam BM,Moritz OL,Khattree N,Chen SC,Goldberg AF, J Biol Chem. September 17, 2004; 279(38):1083-351X.

Altered gating properties of functional Cx26 mutants associated with recessive non-syndromic hearing loss., Meşe G,Londin E,Mui R,Brink PR,White TW, Hum Genet. August 1, 2004; 115(3):1432-1203.

Analysis of missense variation in human BRCA1 in the context of interspecific sequence variation., Abkevich V,Zharkikh A,Deffenbaugh AM,Frank D,Chen Y,Chen Y,Shattuck D,Skolnick MH,Gutin A,Tavtigian SV, J Med Genet. July 1, 2004; 41(7):1468-6244.

A critical role of Pax6 in alcohol-induced fetal microcephaly., Peng Y,Yang PH,Ng SS,Wong OG,Liu J,He ML,Kung HF,Lin MC, Neurobiol Dis. July 1, 2004; 16(2):1095-953X.

Characterization of embryonic cardiac pacemaker and atrioventricular conduction physiology in Xenopus laevis using noninvasive imaging., Bartlett HL,Scholz TD,Lamb FS,Weeks DL, Am J Physiol Heart Circ Physiol. June 1, 2004; 286(6):0363-6135.

Mouse Zic5 deficiency results in neural tube defects and hypoplasia of cephalic neural crest derivatives., Inoue T,Hatayama M,Tohmonda T,Itohara S,Aruga J,Mikoshiba K, Dev Biol. June 1, 2004; 270(1):1095-564X.

Modification of Kv2.1 K+ currents by the silent Kv10 subunits., Vega-Saenz de Miera EC, Brain Res Mol Brain Res. April 7, 2004; 123(1-2):0169-328X.

Identification of a novel gene, FGFR1OP2, fused to FGFR1 in 8p11 myeloproliferative syndrome., Grand EK,Grand FH,Chase AJ,Ross FM,Corcoran MM,Oscier DG,Cross NC, Genes Chromosomes Cancer. May 1, 2004; 40(1):1045-2257.

Aberrant gating, but a normal expression pattern, underlies the recessive phenotype of the deafness mutant Connexin26M34T., Skerrett IM,Di WL,Kasperek EM,Kelsell DP,Nicholson BJ, FASEB J. May 1, 2004; 18(7):1530-6860.

Modulation of DMT1 activity by redox compounds., Marciani P,Trotti D,Hediger MA,Monticelli G, J Membr Biol. January 15, 2004; 197(2):1432-1424.

WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia., Kahle KT,Gimenez I,Hassan H,Wilson FH,Wong RD,Forbush B,Aronson PS,Lifton RP, Proc Natl Acad Sci U S A. February 17, 2004; 101(7):1091-6490.

A single nucleotide polymorphism alters the activity of the renal Na+:Cl- cotransporter and reveals a role for transmembrane segment 4 in chloride and thiazide affinity., Moreno E,Tovar-Palacio C,de los Heros P,Guzmán B,Bobadilla NA,Vázquez N,Riccardi D,Poch E,Gamba G, J Biol Chem. April 16, 2004; 279(16):1083-351X.

Microtransplantation of functional receptors and channels from the Alzheimer's brain to frog oocytes., Miledi R,Dueñas Z,Martinez-Torres A,Kawas CH,Eusebi F, Proc Natl Acad Sci U S A. February 10, 2004; 101(6):1091-6490.

A novel missense mutation in AE1 causing autosomal dominant distal renal tubular acidosis retains normal transport function but is mistargeted in polarized epithelial cells., Rungroj N,Devonald MA,Cuthbert AW,Reimann F,Akkarapatumwong V,Yenchitsomanus PT,Bennett WM,Karet FE, J Biol Chem. April 2, 2004; 279(14):1083-351X.

Functional characterization of two naturally occurring mutations in the human sodium-phosphate cotransporter type IIa., Virkki LV,Forster IC,Hernando N,Biber J,Murer H, J Bone Miner Res. December 1, 2003; 18(12):0884-0431.

Reversed polarized delivery of an aquaporin-2 mutant causes dominant nephrogenic diabetes insipidus., Kamsteeg EJ,Bichet DG,Konings IB,Nivet H,Lonergan M,Arthus MF,van Os CH,Deen PM, J Cell Biol. December 8, 2003; 163(5):1540-8140.

Bisphenol A induces feminization in Xenopus laevis tadpoles., Levy G,Lutz I,Krüger A,Kloas W, Environ Res. January 1, 2004; 94(1):0013-9351.

Pathogenesis of X-linked Charcot-Marie-Tooth disease: differential effects of two mutations in connexin 32., Abrams CK,Freidin M,Bukauskas F,Dobrenis K,Bargiello TA,Verselis VK,Bennett MV,Chen L,Sahenk Z, J Neurosci. November 19, 2003; 23(33):1529-2401.

Mutations linked to generalized epilepsy in humans reduce GABA(A) receptor current., Macdonald RL,Bianchi MT,Bianch MT,Feng H, Exp Neurol. November 1, 2003; 184 Suppl 1:0014-4886.

Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features., Roessler E,Du YZ,Mullor JL,Casas E,Allen WP,Gillessen-Kaesbach G,Roeder ER,Ming JE,Ruiz i Altaba A,Muenke M, Proc Natl Acad Sci U S A. November 11, 2003; 100(23):1091-6490.

Single-channel SCAM identifies pore-lining residues in the first extracellular loop and first transmembrane domains of Cx46 hemichannels., Kronengold J,Trexler EB,Bukauskas FF,Bargiello TA,Verselis VK, J Gen Physiol. October 1, 2003; 122(4):1540-7748.

Transcriptional and translational regulation of the Leri-Weill and Turner syndrome homeobox gene SHOX., Blaschke RJ,Töpfer C,Marchini A,Steinbeisser H,Janssen JW,Rappold GA, J Biol Chem. November 28, 2003; 278(48):1083-351X.

Zebrafish Cx35: cloning and characterization of a gap junction gene highly expressed in the retina., McLachlan E,White TW,Ugonabo C,Olson C,Nagy JI,Valdimarsson G, J Neurosci Res. September 15, 2003; 73(6):1097-4547.

Molecular motions of the outer ring of charge of the sodium channel: do they couple to slow inactivation?, Xiong W,Li RA,Tian Y,Tomaselli GF, J Gen Physiol. September 1, 2003; 122(3):1540-7748.

The role of ZIC3 in vertebrate development., Herman GE,El-Hodiri HM, Cytogenet Genome Res. January 1, 2002; 99(1-4):1424-859X.

Opsin activation as a cause of congenital night blindness., Jin S,Cornwall MC,Oprian DD, Nat Neurosci. July 1, 2003; 6(7):1546-1726.

Functional characterization of a glutamate/aspartate transporter from the mosquito Aedes aegypti., Umesh A,Cohen BN,Ross LS,Gill SS, J Exp Biol. July 1, 2003; 206(Pt 13):1477-9145.

Down-regulation of GABA-transporter function by hippocampal translation products: its possible role in epilepsy., Fueta Y,Vasilets LA,Takeda K,Kawamura M,Schwarz W, Neuroscience. January 1, 2003; 118(2):1873-7544.

Effects of Chinese domestic polychlorinated biphenyls (PCBs) on gonadal differentiation in Xenopus laevis., Qin ZF,Zhou JM,Chu SG,Xu XB, Environ Health Perspect. April 1, 2003; 111(4):0091-6765.

Acute regulation of the SLC26A3 congenital chloride diarrhoea anion exchanger (DRA) expressed in Xenopus oocytes., Chernova MN,Jiang L,Shmukler BE,Schweinfest CW,Blanco P,Freedman SD,Stewart AK,Alper SL, J Physiol. May 15, 2003; 549(Pt 1):0022-3751.

Amyloid beta(1-42) peptide alters the gating of human and mouse alpha-bungarotoxin-sensitive nicotinic receptors., Grassi F,Palma E,Tonini R,Amici M,Ballivet M,Eusebi F, J Physiol. February 15, 2003; 547(Pt 1):0022-3751.

Response of larval Xenopus laevis to atrazine: assessment of growth, metamorphosis, and gonadal and laryngeal morphology., Carr JA,Gentles A,Smith EE,Goleman WL,Urquidi LJ,Thuett K,Kendall RJ,Giesy JP,Gross TS,Solomon KR,Van Der Kraak G, Environ Toxicol Chem. February 1, 2003; 22(2):1552-8618.

Investigation of nuclear architecture with a domain-presenting expression system., Dreger CK,König AR,Spring H,Lichter P,Herrmann H, J Struct Biol. January 1, 2002; 140(1-3):1047-8477.

Functional and biochemical analysis of a sodium channel beta1 subunit mutation responsible for generalized epilepsy with febrile seizures plus type 1., Meadows LS,Malhotra J,Loukas A,Thyagarajan V,Kazen-Gillespie KA,Koopman MC,Kriegler S,Isom LL,Ragsdale DS, J Neurosci. December 15, 2002; 22(24):1529-2401.

Abnormal Tau phosphorylation of the Alzheimer-type also occurs during mitosis., Delobel P,Flament S,Hamdane M,Mailliot C,Sambo AV,Bégard S,Sergeant N,Delacourte A,Vilain JP,Buée L, J Neurochem. October 1, 2002; 83(2):1471-4159.

The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro., Guipponi M,Vuagniaux G,Wattenhofer M,Shibuya K,Vazquez M,Dougherty L,Scamuffa N,Guida E,Okui M,Rossier C,Hancock M,Buchet K,Reymond A,Hummler E,Marzella PL,Kudoh J,Shimizu N,Scott HS,Antonarakis SE,Rossier BC, Hum Mol Genet. November 1, 2002; 11(23):1460-2083.

The K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum., Howard HC,Mount DB,Rochefort D,Byun N,Dupré N,Lu J,Fan X,Song L,Rivière JB,Prévost C,Horst J,Simonati A,Lemcke B,Welch R,England R,Zhan FQ,Mercado A,Siesser WB,George AL,McDonald MP,Bouchard JP,Mathieu J,Delpire E,Rouleau GA, Nat Genet. November 1, 2002; 32(3):1546-1718.

Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy., Robitaille J,MacDonald ML,Kaykas A,Sheldahl LC,Zeisler J,Dubé MP,Zhang LH,Singaraja RR,Guernsey DL,Zheng B,Siebert LF,Hoskin-Mott A,Trese MT,Pimstone SN,Shastry BS,Moon RT,Hayden MR,Goldberg YP,Samuels ME, Nat Genet. October 1, 2002; 32(2):1546-1718.

Functional characterization of compound heterozygosity for GlyRalpha1 mutations in the startle disease hyperekplexia., Rea R,Tijssen MA,Herd C,Frants RR,Kullmann DM, Eur J Neurosci. July 1, 2002; 16(2):1460-9568.

Identification and molecular cloning of Xenopus laevis SP22, a protein associated with fertilization in mammals., Monetti C,Vigetti D,Gornati R,Prati M,Klinefelter GR,Bernardini G, Comp Biochem Physiol B Biochem Mol Biol. August 1, 2002; 132(4):1096-4959.

Two different mechanisms of disinhibition produced by GABAA receptor mutations linked to epilepsy in humans., Bianchi MT,Song L,Zhang H,Macdonald RL, J Neurosci. July 1, 2002; 22(13):1529-2401.

Two novel aquaporin-2 mutations responsible for congenital nephrogenic diabetes insipidus in Chinese families., Lin SH,Bichet DG,Sasaki S,Kuwahara M,Arthus MF,Lonergan M,Lin YF, J Clin Endocrinol Metab. June 1, 2002; 87(6):0021-972X.

Functional expression of mutations in the human NaCl cotransporter: evidence for impaired routing mechanisms in Gitelman's syndrome., De Jong JC,Van Der Vliet WA,Van Den Heuvel LP,Willems PH,Knoers NV,Bindels RJ, J Am Soc Nephrol. June 1, 2002; 13(6):1533-3450.

Heteromerization of Kir2.x potassium channels contributes to the phenotype of Andersen's syndrome., Preisig-Müller R,Schlichthörl G,Goerge T,Heinen S,Brüggemann A,Rajan S,Derst C,Veh RW,Daut J, Proc Natl Acad Sci U S A. May 28, 2002; 99(11):1091-6490.

Hermaphroditic, demasculinized frogs after exposure to the herbicide atrazine at low ecologically relevant doses., Hayes TB,Collins A,Lee M,Mendoza M,Noriega N,Stuart AA,Vonk A, Proc Natl Acad Sci U S A. April 16, 2002; 99(8):1091-6490.

Modelling Alzheimer-specific abnormal Tau phosphorylation independently of GSK3beta and PKA kinase activities., Delobel P,Flament S,Hamdane M,Delacourte A,Vilain JP,Buée L, FEBS Lett. April 10, 2002; 516(1-3):1873-3468.

Hedgehog signaling in gastrointestinal development and disease., Harmon EB,Ko AH,Kim SK, Curr Mol Med. February 1, 2002; 2(1):1875-5666.

Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning., Davis RL,Turner DL, Oncogene. December 20, 2001; 20(58):0950-9232.

Expression of the gene encoding the beta-amyloid precursor protein APP in Xenopus laevis., van den Hurk WH,Bloemen M,Martens GJ, Brain Res Mol Brain Res. December 16, 2001; 97(1):0169-328X.

Human disease-causing NOG missense mutations: effects on noggin secretion, dimer formation, and bone morphogenetic protein binding., Marcelino J,Sciortino CM,Romero MF,Ulatowski LM,Ballock RT,Economides AN,Eimon PM,Harland RM,Warman ML, Proc Natl Acad Sci U S A. September 25, 2001; 98(20):1091-6490.

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Lessons from the lily pad: Using Xenopus to understand heart disease., Bartlett HL,Weeks DL, Drug Discov Today Dis Models. January 1, 2008; 5(3):1740-6757.

A functional null mutation of SCN1B in a patient with Dravet syndrome., Patino GA,Claes LR,Lopez-Santiago LF,Slat EA,Dondeti RS,Chen C,O'Malley HA,Gray CB,Miyazaki H,Nukina N,Oyama F,De Jonghe P,Isom LL, J Neurosci. August 26, 2009; 29(34):1529-2401.

A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels., Gustina AS,Trudeau MC, Proc Natl Acad Sci U S A. August 4, 2009; 106(31):1091-6490.

Learning about cancer from frogs: analysis of mitotic spindles in Xenopus egg extracts., Cross MK,Powers MA, Dis Model Mech. January 1, 2009; 2(11-12):1754-8411.

The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1., Agrawal R,Tran U,Wessely O, Development. December 1, 2009; 136(23):1477-9129.

Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors., Landais I,Hiddingh S,McCarroll M,Yang C,Sun A,Turker MS,Snyder JP,Hoatlin ME, Mol Cancer. December 31, 2009; 8:1476-4598.

The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate., Li Y,Trojer P,Xu CF,Cheung P,Kuo A,Drury WJ,Qiao Q,Neubert TA,Xu RM,Gozani O,Reinberg D, J Biol Chem. December 4, 2009; 284(49):1083-351X.

A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival., Rauschenberger K,Schöler K,Sass JO,Sauer S,Djuric Z,Rumig C,Wolf NI,Okun JG,Kölker S,Schwarz H,Fischer C,Grziwa B,Runz H,Nümann A,Shafqat N,Kavanagh KL,Hämmerling G,Wanders RJ,Shield JP,Wendel U,Stern D,Nawroth P,Hoffmann GF,Bartram CR,Arnold B,Bierhaus A,Oppermann U,Steinbeisser H,Zschocke J, EMBO Mol Med. February 1, 2010; 2(2):1757-4684.

GJB2 mutations in Mongolia: complex alleles, low frequency, and reduced fitness of the deaf., Tekin M,Xia XJ,Erdenetungalag R,Cengiz FB,White TW,Radnaabazar J,Dangaasuren B,Tastan H,Nance WE,Pandya A, Ann Hum Genet. March 1, 2010; 74(2):1469-1809.

Atrazine induces complete feminization and chemical castration in male African clawed frogs (Xenopus laevis)., Hayes TB,Khoury V,Narayan A,Nazir M,Park A,Brown T,Adame L,Chan E,Buchholz D,Stueve T,Gallipeau S, Proc Natl Acad Sci U S A. March 9, 2010; 107(10):1091-6490.

Regulated transport of sulfate and oxalate by SLC26A2/DTDST., Heneghan JF,Akhavein A,Salas MJ,Shmukler BE,Karniski LP,Vandorpe DH,Alper SL, Am J Physiol Cell Physiol. June 1, 2010; 298(6):1522-1563.

APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex., Shimomura Y,Agalliu D,Vonica A,Luria V,Wajid M,Baumer A,Belli S,Petukhova L,Schinzel A,Brivanlou AH,Brivanlou AH,Barres BA,Christiano AM, Nature. April 15, 2010; 464(7291):0143-5221.

Testing the effects of FSHD candidate gene expression in vertebrate muscle development., Wuebbles RD,Long SW,Hanel ML,Jones PL, Int J Clin Exp Pathol. March 28, 2010; 3(4):1936-2625.

The BMP pathway acts to directly regulate Tbx20 in the developing heart., Mandel EM,Kaltenbrun E,Callis TE,Zeng XX,Marques SR,Yelon D,Wang DZ,Conlon FL, Development. June 1, 2010; 137(11):1477-9129.

Enhancement of GABA(A)-current run-down in the hippocampus occurs at the first spontaneous seizure in a model of temporal lobe epilepsy., Mazzuferi M,Palma E,Martinello K,Maiolino F,Roseti C,Fucile S,Fabene PF,Schio F,Pellitteri M,Sperk G,Miledi R,Eusebi F,Simonato M, Proc Natl Acad Sci U S A. February 16, 2010; 107(7):1091-6490.

Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force., Loukin S,Zhou X,Zhou X,Su Z,Saimi Y,Kung C, J Biol Chem. August 27, 2010; 285(35):1083-351X.

An epilepsy/dyskinesia-associated mutation enhances BK channel activation by potentiating Ca2+ sensing., Yang J,Krishnamoorthy G,Saxena A,Zhang G,Shi J,Yang H,Delaloye K,Sept D,Cui J, Neuron. June 24, 2010; 66(6):0896-6273.

A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels., Gradogna A,Babini E,Picollo A,Pusch M, J Gen Physiol. September 1, 2010; 136(3):1540-7748.

Proton block of the CLC-5 Cl-/H+ exchanger., Picollo A,Malvezzi M,Accardi A, J Gen Physiol. June 1, 2010; 135(6):1540-7748.

Polycystin-2 activity is controlled by transcriptional coactivator with PDZ binding motif and PALS1-associated tight junction protein., Duning K,Rosenbusch D,Schlüter MA,Tian Y,Kunzelmann K,Meyer N,Schulze U,Markoff A,Pavenstädt H,Weide T, J Biol Chem. October 29, 2010; 285(44):1083-351X.

Small molecule disruption of G beta gamma signaling inhibits the progression of heart failure., Casey LM,Pistner AR,Belmonte SL,Migdalovich D,Stolpnik O,Nwakanma FE,Vorobiof G,Dunaevsky O,Matavel A,Lopes CM,Smrcka AV,Blaxall BC, Circ Res. August 20, 2010; 107(4):1524-4571.

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Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α., Thorne CA,Hanson AJ,Schneider J,Tahinci E,Orton D,Cselenyi CS,Jernigan KK,Meyers KC,Hang BI,Waterson AG,Kim K,Melancon B,Ghidu VP,Sulikowski GA,LaFleur B,Salic A,Lee LA,Miller DM,Lee E,Lee E, Nat Chem Biol. November 1, 2010; 6(11):1552-4469.

Inversin relays Frizzled-8 signals to promote proximal pronephros development., Lienkamp S,Ganner A,Boehlke C,Schmidt T,Arnold SJ,Schäfer T,Romaker D,Schuler J,Hoff S,Powelske C,Eifler A,Krönig C,Bullerkotte A,Nitschke R,Kuehn EW,Kim E,Burkhardt H,Brox T,Ronneberger O,Gloy J,Walz G, Proc Natl Acad Sci U S A. November 23, 2010; 107(47):1091-6490.

Multiple enhancers located in a 1-Mb region upstream of POU3F4 promote expression during inner ear development and may be required for hearing., Naranjo S,Voesenek K,de la Calle-Mustienes E,Robert-Moreno A,Kokotas H,Grigoriadou M,Economides J,Van Camp G,Hilgert N,Moreno F,Alsina B,Petersen MB,Kremer H,Gómez-Skarmeta JL, Hum Genet. October 1, 2010; 128(4):1432-1203.

Potential role of caveolin-1-positive domains in the regulation of the acetylcholine receptor's activatable pool: implications in the pathogenesis of a novel congenital myasthenic syndrome., Báez-Pagán CA,Martínez-Ortiz Y,Otero-Cruz JD,Salgado-Villanueva IK,Velázquez G,Ortiz-Acevedo A,Quesada O,Silva WI,Lasalde-Dominicci JA, Channels (Austin). January 1, 2008; 2(3):1933-6969.

Tamm-Horsfall glycoprotein interacts with renal outer medullary potassium channel ROMK2 and regulates its function., Renigunta A,Renigunta V,Saritas T,Decher N,Mutig K,Waldegger S, J Biol Chem. January 21, 2011; 286(3):1083-351X.

Animal models for autosomal dominant frontal lobe epilepsy: on the origin of seizures., Steinlein OK, Expert Rev Neurother. December 1, 2010; 10(12):1744-8360.

ATP induces conformational changes in the carboxyl-terminal region of ClC-5., Wellhauser L,Luna-Chavez C,D'Antonio C,Tainer J,Bear CE, J Biol Chem. February 25, 2011; 286(8):1083-351X.

An essential role of the cysteine-rich domain of FZD4 in Norrin/Wnt signaling and familial exudative vitreoretinopathy., Zhang K,Harada Y,Wei X,Shukla D,Rajendran A,Tawansy K,Bedell M,Lim S,Shaw PX,He X,Yang Z, J Biol Chem. March 25, 2011; 286(12):1083-351X.

Biophysical properties of mutant KCNQ1 S277L channels linked to hereditary long QT syndrome with phenotypic variability., Aidery P,Kisselbach J,Schweizer PA,Becker R,Katus HA,Thomas D, Biochim Biophys Acta. April 1, 2011; 1812(4):0006-3002.

A homozygous nonsense mutation (c.214C->A) in the biliverdin reductase alpha gene (BLVRA) results in accumulation of biliverdin during episodes of cholestasis., Nytofte NS,Serrano MA,Monte MJ,Gonzalez-Sanchez E,Tumer Z,Ladefoged K,Briz O,Marin JJ, J Med Genet. April 1, 2011; 48(4):1468-6244.

Specification of ion transport cells in the Xenopus larval skin., Quigley IK,Stubbs JL,Kintner C, Development. February 1, 2011; 138(4):1477-9129.

Functional and developmental expression of a zebrafish Kir1.1 (ROMK) potassium channel homologue Kcnj1., Abbas L,Hajihashemi S,Stead LF,Cooper GJ,Ware TL,Munsey TS,Whitfield TT,White SJ, J Physiol. March 15, 2011; 589(Pt 6):0022-3751.

RG3487, a novel nicotinic α7 receptor partial agonist, improves cognition and sensorimotor gating in rodents., Wallace TL,Callahan PM,Tehim A,Bertrand D,Tombaugh G,Wang S,Xie W,Rowe WB,Ong V,Graham E,Terry AV,Rodefer JS,Herbert B,Murray M,Porter R,Santarelli L,Lowe DA, J Pharmacol Exp Ther. January 1, 2011; 336(1):1521-0103.

Episodic ataxia type 1 mutations affect fast inactivation of K+ channels by a reduction in either subunit surface expression or affinity for inactivation domain., Imbrici P,D'Adamo MC,Grottesi A,Biscarini A,Pessia M, Am J Physiol Cell Physiol. June 1, 2011; 300(6):1522-1563.

A neuroprotective role for polyamines in a Xenopus tadpole model of epilepsy., Bell MR,Belarde JA,Johnson HF,Aizenman CD, Nat Neurosci. April 1, 2011; 14(4):1546-1726.

ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair., Cosentino C,Grieco D,Costanzo V, EMBO J. February 2, 2011; 30(3):0261-4189.

Embryonic frog epidermis: a model for the study of cell-cell interactions in the development of mucociliary disease., Dubaissi E,Papalopulu N, Dis Model Mech. March 1, 2011; 4(2):1754-8411.

Allosteric modulation of related ligand-gated ion channels synergistically induces long-term potentiation in the hippocampus and enhances cognition., Johnstone TB,Gu Z,Yoshimura RF,Villegier AS,Hogenkamp DJ,Whittemore ER,Huang JC,Tran MB,Belluzzi JD,Yakel JL,Gee KW, J Pharmacol Exp Ther. March 1, 2011; 336(3):1521-0103.

Xenopus: An emerging model for studying congenital heart disease., Kaltenbrun E,Tandon P,Amin NM,Waldron L,Showell C,Conlon FL, Birth Defects Res A Clin Mol Teratol. June 1, 2011; 91(6):1542-0760.

Insights on the evolution of prolyl 3-hydroxylation sites from comparative analysis of chicken and Xenopus fibrillar collagens., Hudson DM,Weis M,Eyre DR, PLoS One. May 3, 2011; 6(5):1932-6203.

Epigenetic reprogramming of breast cancer cells with oocyte extracts., Allegrucci C,Rushton MD,Dixon JE,Sottile V,Shah M,Kumari R,Watson S,Alberio R,Johnson AD, Mol Cancer. January 13, 2011; 10(1):1476-4598.

CNBP: a multifunctional nucleic acid chaperone involved in cell death and proliferation control., Calcaterra NB,Armas P,Weiner AM,Borgognone M, IUBMB Life. October 1, 2010; 62(10):1521-6543.

The cataract-associated protein TMEM114, and TMEM235, are glycosylated transmembrane proteins that are distinct from claudin family members., Maher GJ,Hilton EN,Urquhart JE,Davidson AE,Spencer HL,Black GC,Manson FD, FEBS Lett. July 21, 2011; 585(14):1873-3468.

Examining the cardiac NK-2 genes in early heart development., Bartlett H,Veenstra GJ,Weeks DL, Pediatr Cardiol. April 1, 2010; 31(3):1432-1971.

Stomatin-deficient cryohydrocytosis results from mutations in SLC2A1: a novel form of GLUT1 deficiency syndrome., Flatt JF,Guizouarn H,Burton NM,Borgese F,Tomlinson RJ,Forsyth RJ,Baldwin SA,Levinson BE,Quittet P,Aguilar-Martinez P,Delaunay J,Stewart GW,Bruce LJ, Blood. November 10, 2011; 118(19):1528-0020.

Identification and functional characterization of KCNQ1 mutations around the exon 7-intron 7 junction affecting the splicing process., Tsuji-Wakisaka K,Akao M,Ishii TM,Ashihara T,Makiyama T,Ohno S,Toyoda F,Dochi K,Matsuura H,Horie M, Biochim Biophys Acta. November 1, 2011; 1812(11):0006-3002.

Over-expression of atf4 in Xenopus embryos interferes with neurogenesis and eye formation., Liu JT,Yang Y,Yang Y,Guo XG,Chen M,Ding HZ,Chen YL,Chen YL,Wang MR, Dongwuxue Yanjiu. October 1, 2011; 32(5):2095-8137.

Structural basis of slow activation gating in the cardiac I Ks channel complex., Strutz-Seebohm N,Pusch M,Wolf S,Stoll R,Tapken D,Gerwert K,Attali B,Seebohm G, Cell Physiol Biochem. January 1, 2011; 27(5):1421-9778.

Intercellular signaling pathways active during and after growth and differentiation of the lumbar vertebral growth plate., Dahia CL,Mahoney EJ,Durrani AA,Wylie C, Spine (Phila Pa 1976). June 15, 2011; 36(14):1528-1159.

Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures., Ishida S,Sakamoto Y,Nishio T,Baulac S,Kuwamura M,Ohno Y,Takizawa A,Kaneko S,Serikawa T,Mashimo T, Dev Biol. January 30, 2012; 1435:0012-1606.

SHP-2 acts via ROCK to regulate the cardiac actin cytoskeleton., Langdon Y,Tandon P,Paden E,Duddy J,Taylor JM,Conlon FL, Development. March 1, 2012; 139(5):1477-9129.

GlialCAM, a protein defective in a leukodystrophy, serves as a ClC-2 Cl(-) channel auxiliary subunit., Jeworutzki E,López-Hernández T,Capdevila-Nortes X,Sirisi S,Bengtsson L,Montolio M,Zifarelli G,Arnedo T,Müller CS,Schulte U,Nunes V,Martínez A,Jentsch TJ,Gasull X,Pusch M,Estévez R, Neuron. March 8, 2012; 73(5):0896-6273.

Thiol-reactive compounds from garlic inhibit the epithelial sodium channel (ENaC)., Krumm P,Giraldez T,Alvarez de la Rosa D,Clauss WG,Fronius M,Althaus M, Bioorg Med Chem. July 1, 2012; 20(13):1464-3391.

Xenopus as a model system for the study of GOLPH2/GP73 function: Xenopus GOLPH2 is required for pronephros development., Li L,Wen L,Gong Y,Mei G,Liu J,Chen Y,Chen Y,Peng T, PLoS One. January 1, 2012; 7(6):1932-6203.

Suppression of Bmp4 signaling by the zinc-finger repressors Osr1 and Osr2 is required for Wnt/β-catenin-mediated lung specification in Xenopus., Rankin SA,Rankin SA,Gallas AL,Neto A,Gómez-Skarmeta JL,Zorn AM, Development. August 1, 2012; 139(16):1477-9129.

Dominantly inherited myotonia congenita resulting from a mutation that increases open probability of the muscle chloride channel CLC-1., Richman DP,Yu Y,Lee TT,Tseng PY,Yu WP,Maselli RA,Tang CY,Chen TY, Neuromolecular Med. December 1, 2012; 14(4):1559-1174.

Isthmin inhibits glioma growth through antiangiogenesis in vivo., Yuan B,Xian R,Ma J,Chen Y,Chen Y,Lin C,Song Y, J Neurooncol. September 1, 2012; 109(2):1573-7373.

Acetylcholine receptor gating in a zebrafish model for slow-channel syndrome., Walogorsky M,Mongeon R,Wen H,Mandel G,Brehm P, J Neurosci. June 6, 2012; 32(23):1529-2401.

Condensins: universal organizers of chromosomes with diverse functions., Hirano T, Genes Dev. August 1, 2012; 26(15):1549-5477.

Live imaging of targeted cell ablation in Xenopus: a new model to study demyelination and repair., Kaya F,Mannioui A,Chesneau A,Sekizar S,Maillard E,Ballagny C,Houel-Renault L,Dupasquier D,Bronchain O,Holtzmann I,Desmazieres A,Thomas JL,Demeneix BA,Brophy PJ,Zalc B,Mazabraud A, J Neurosci. September 12, 2012; 32(37):1529-2401.

Impaired ion channel function related to a common KCNQ1 mutation - implications for risk stratification in long QT syndrome 1., Aidery P,Kisselbach J,Schweizer PA,Becker R,Katus HA,Thomas D, Gene. December 10, 2012; 511(1):1879-0038.

Generation of albino Xenopus tropicalis using zinc-finger nucleases., Nakajima K,Nakajima T,Takase M,Yaoita Y, Dev Growth Differ. December 1, 2012; 54(9):1440-169X.

Functional and structural effects of amyloid-β aggregate on Xenopus laevis oocytes., Parodi J,Ochoa-de la Paz L,Miledi R,Martínez-Torres A, Mol Cells. October 1, 2012; 34(4):0219-1032.

An MIP/AQP0 mutation with impaired trafficking and function underlies an autosomal dominant congenital lamellar cataract., Senthil Kumar G,Kyle JW,Minogue PJ,Dinesh Kumar K,Vasantha K,Berthoud VM,Beyer EC,Santhiya ST, Exp Eye Res. May 1, 2013; 110:0014-4835.

Embryonic exposure to propylthiouracil disrupts left-right patterning in Xenopus embryos., van Veenendaal NR,Ulmer B,Boskovski MT,Fang X,Khokha MK,Wendler CC,Blum M,Rivkees SA, FASEB J. February 1, 2013; 27(2):1530-6860.

Functional analysis of nonsynonymous single nucleotide polymorphisms in human SLC26A9., Chen AP,Chang MH,Romero MF, Hum Mutat. August 1, 2012; 33(8):1098-1004.

The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling., Wang F,Hu W,Xian J,Ohnuma S,Brenton JD, Dev Biol. July 1, 2013; 379(1):1095-564X.

Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase., Sareen A,Chaudhury I,Adams N,Sobeck A, Nucleic Acids Res. September 1, 2012; 40(17):1362-4962.

Imbalance of Hsp70 family variants fosters tau accumulation., Jinwal UK,Akoury E,Abisambra JF,O'Leary JC,Thompson AD,Blair LJ,Jin Y,Bacon J,Nordhues BA,Cockman M,Zhang J,Li P,Zhang B,Borysov S,Uversky VN,Biernat J,Mandelkow E,Gestwicki JE,Zweckstetter M,Dickey CA, FASEB J. April 1, 2013; 27(4):1530-6860.

Early infantile epileptic encephalopathy associated with a high voltage gated calcium channelopathy., Edvardson S,Oz S,Abulhijaa FA,Taher FB,Shaag A,Zenvirt S,Dascal N,Elpeleg O, J Med Genet. February 1, 2013; 50(2):1468-6244.

Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation., Streets AJ,Wessely O,Peters DJ,Ong AC, Hum Mol Genet. May 15, 2013; 22(10):1460-2083.

Functional analysis of missense mutations in Kv8.2 causing cone dystrophy with supernormal rod electroretinogram., Smith KE,Wilkie SE,Tebbs-Warner JT,Jarvis BJ,Gallasch L,Stocker M,Hunt DM, J Biol Chem. December 21, 2012; 287(52):1083-351X.

Restricted neural plasticity in vestibulospinal pathways after unilateral labyrinthectomy as the origin for scoliotic deformations., Lambert FM,Malinvaud D,Gratacap M,Straka H,Vidal PP, J Neurosci. April 17, 2013; 33(16):1529-2401.

Connexins in epidermal homeostasis and skin disease., Scott CA,Tattersall D,O'Toole EA,Kelsell DP, Biochim Biophys Acta. August 1, 2012; 1818(8):0006-3002.

Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells., De Robertis A,Valensin S,Rossi M,Tunici P,Verani M,De Rosa A,Giordano C,Varrone M,Nencini A,Pratelli C,Benicchi T,Bakker A,Hill J,Sangthongpitag K,Pendharkar V,Liu B,Ng FM,Then SW,Jing Tai S,Cheong SM,He X,Caricasole A,Salerno M, Mol Cancer Ther. July 1, 2013; 12(7):1538-8514.

Bcl6a function is required during optic cup formation to prevent p53-dependent apoptosis and colobomata., Lee J,Lee J,Lee BK,Gross JM, Hum Mol Genet. September 1, 2013; 22(17):1460-2083.

Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules., Woodward OM,Tukaye DN,Cui J,Greenwell P,Constantoulakis LM,Parker BS,Rao A,Köttgen M,Maloney PC,Guggino WB, Proc Natl Acad Sci U S A. March 26, 2013; 110(13):1091-6490.

MCTP2 is a dosage-sensitive gene required for cardiac outflow tract development., Lalani SR,Ware SM,Wang X,Zapata G,Tian Q,Franco LM,Jiang Z,Jiang Z,Bucasas K,Scott DA,Campeau PM,Hanchard N,Umaña L,Cast A,Patel A,Cheung SW,McBride KL,Bray M,Craig Chinault A,Boggs BA,Huang M,Baker MR,Hamilton S,Towbin J,Jefferies JL,Fernbach SD,Potocki L,Belmont JW, Hum Mol Genet. November 1, 2013; 22(21):1460-2083.

Disease-associated mutations in CNGB3 promote cytotoxicity in photoreceptor-derived cells., Liu C,Sherpa T,Varnum MD, Mol Vis. June 11, 2013; 19:1090-0535.

ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3., Hoff S,Halbritter J,Epting D,Frank V,Nguyen TM,van Reeuwijk J,Boehlke C,Schell C,Yasunaga T,Helmstädter M,Mergen M,Filhol E,Boldt K,Horn N,Ueffing M,Otto EA,Eisenberger T,Elting MW,van Wijk JA,Bockenhauer D,Sebire NJ,Rittig S,Vyberg M,Ring T,Pohl M,Pape L,Neuhaus TJ,Elshakhs NA,Koon SJ,Harris PC,Grahammer F,Huber TB,Kuehn EW,Kramer-Zucker A,Bolz HJ,Roepman R,Saunier S,Walz G,Hildebrandt F,Bergmann C,Lienkamp SS, Nat Genet. August 1, 2013; 45(8):1546-1718.

Ciliogenesis and cerebrospinal fluid flow in the developing Xenopus brain are regulated by foxj1., Hagenlocher C,Walentek P,M Ller C,Thumberger T,Feistel K, Cilia. April 29, 2013; 2(1):2046-2530.

GRIN2B mutations in West syndrome and intellectual disability with focal epilepsy., Lemke JR,Hendrickx R,Geider K,Laube B,Schwake M,Harvey RJ,James VM,Pepler A,Steiner I,Hörtnagel K,Neidhardt J,Ruf S,Wolff M,Bartholdi D,Caraballo R,Platzer K,Suls A,De Jonghe P,Biskup S,Weckhuysen S, Ann Neurol. January 1, 2014; 75(1):1531-8249.

Characterization of SLC26A9 in patients with CF-like lung disease., Bakouh N,Bienvenu T,Thomas A,Ehrenfeld J,Liote H,Roussel D,Duquesnoy P,Farman N,Viel M,Cherif-Zahar B,Amselem S,Taam RA,Edelman A,Planelles G,Sermet-Gaudelus I, Hum Mutat. October 1, 2013; 34(10):1098-1004.

Essential roles of LEM-domain protein MAN1 during organogenesis in Xenopus laevis and overlapping functions of emerin., Reil M,Dabauvalle MC, Eur J Cell Biol. January 1, 2013; 92(8-9):0171-9335.

The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality., Boskovski MT,Yuan S,Pedersen NB,Goth CK,Makova S,Clausen H,Brueckner M,Khokha MK, Nature. December 19, 2013; 504(7480):0143-5221.

Cardiac expression and atrial fibrillation-associated remodeling of K₂p2.1 (TREK-1) K⁺ channels in a porcine model., Schmidt C,Wiedmann F,Tristram F,Anand P,Wenzel W,Lugenbiel P,Schweizer PA,Katus HA,Thomas D, Life Sci. March 3, 2014; 97(2):0024-3205.

The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT., Mechakra A,Vincent Y,Chevalier P,Millat G,Ficker E,Jastrzebski M,Poulin H,Pouliot V,Chahine M,Christé G, Gene. February 25, 2014; 536(2):1879-0038.

KCNJ10 mutations display differential sensitivity to heteromerisation with KCNJ16., Parrock S,Hussain S,Issler N,Differ AM,Lench N,Guarino S,Oosterveld MJ,Keijzer-Veen M,Brilstra E,van Wieringen H,Konijnenberg AY,Amin-Rasip S,Dumitriu S,Klootwijk E,Knoers N,Bockenhauer D,Kleta R,Zdebik AA, Nephron Physiol. January 1, 2013; 123(3-4):1660-2137.

Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis., Nakayama T,Fish MB,Fisher M,Oomen-Hajagos J,Thomsen GH,Grainger RM, Genesis. December 1, 2013; 51(12):1526-968X.

Functional characterization of an AQP0 missense mutation, R33C, that causes dominant congenital lens cataract, reveals impaired cell-to-cell adhesion., Kumari SS,Gandhi J,Mustehsan MH,Eren S,Varadaraj K, Exp Eye Res. November 1, 2013; 116:0014-4835.

Propofol modulation of α1 glycine receptors does not require a structural transition at adjacent subunits that is crucial to agonist-induced activation., Lynagh T,Kunz A,Laube B, ACS Chem Neurosci. November 20, 2013; 4(11):1948-7193.

The severe autosomal dominant retinitis pigmentosa rhodopsin mutant Ter349Glu mislocalizes and induces rapid rod cell death., Hollingsworth TJ,Gross AK, J Biol Chem. October 4, 2013; 288(40):1083-351X.

ZC88, a novel 4-amino piperidine analog, inhibits the growth of neuroblastoma cells through blocking hERG potassium channel., Wei X,Sun H,Yan H,Zhang C,Zhang S,Liu X,Hua N,Ma X,Zheng J, Cancer Biol Ther. May 1, 2013; 14(5):1555-8576.

The retinal pigment epithelium: an important player of retinal disorders and regeneration., Chiba C, Exp Eye Res. June 1, 2014; 123:0014-4835.

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A mutation in TGFB3 associated with a syndrome of low muscle mass, growth retardation, distal arthrogryposis and clinical features overlapping with Marfan and Loeys-Dietz syndrome., Rienhoff HY,Yeo CY,Morissette R,Khrebtukova I,Melnick J,Luo S,Leng N,Kim YJ,Schroth G,Westwick J,Vogel H,McDonnell N,Hall JG,Whitman M, Am J Med Genet A. August 1, 2013; 161A(8):1552-4833.

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Identification of compound heterozygous KCNJ1 mutations (encoding ROMK) in a kindred with Bartter's syndrome and a functional analysis of their pathogenicity., Srivastava S,Li D,Edwards N,Hynes AM,Wood K,Al-Hamed M,Wroe AC,Reaich D,Moochhala SH,Welling PA,Sayer JA, Physiol Rep. November 1, 2013; 1(6):2051-817X.

A potential molecular pathogenesis of cardiac/laterality defects in Oculo-Facio-Cardio-Dental syndrome., Tanaka K,Kato A,Angelocci C,Watanabe M,Kato Y, Dev Biol. March 1, 2014; 387(1):1095-564X.

The unusual stoichiometry of ADP activation of the KATP channel., Hosy E,Vivaudou M, Front Physiol. January 28, 2014; 5:1664-042X.

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A single codon insertion in PICALM is associated with development of familial subvalvular aortic stenosis in Newfoundland dogs., Stern JA,White SN,Lehmkuhl LB,Reina-Doreste Y,Ferguson JL,Nascone-Yoder NM,Meurs KM, Hum Genet. September 1, 2014; 133(9):1432-1203.

Congenital ataxia and hemiplegic migraine with cerebral edema associated with a novel gain of function mutation in the calcium channel CACNA1A., García Segarra N,Gautschi I,Mittaz-Crettol L,Kallay Zetchi C,Al-Qusairi L,Van Bemmelen MX,Maeder P,Bonafé L,Schild L,Roulet-Perez E, J Neurol Sci. July 15, 2014; 342(1-2):1878-5883.

The molecular mechanism of intestinal levodopa absorption and its possible implications for the treatment of Parkinson's disease., Camargo SM,Vuille-dit-Bille RN,Mariotta L,Ramadan T,Huggel K,Singer D,Götze O,Verrey F, J Pharmacol Exp Ther. October 1, 2014; 351(1):1521-0103.

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Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy., Simons C,Rash LD,Crawford J,Ma L,Cristofori-Armstrong B,Miller D,Ru K,Baillie GJ,Alanay Y,Jacquinet A,Debray FG,Verloes A,Shen J,Yesil G,Guler S,Yuksel A,Cleary JG,Grimmond SM,McGaughran J,King GF,Gabbett MT,Taft RJ, Nat Genet. January 1, 2015; 47(1):1546-1718.

Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels., Vingtdeux V,Tanis JE,Chandakkar P,Zhao H,Dreses-Werringloer U,Campagne F,Foskett JK,Marambaud P, PLoS One. November 6, 2014; 9(11):1932-6203.

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Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG,Predes D,Fonseca BF,Cerqueira DM,Reis AH,Dudenhoeffer AC,Borges HL,Mendes FA,Abreu JG, J Biol Chem. December 19, 2014; 289(51):1083-351X.

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Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character., Fish MB,Nakayama T,Fisher M,Hirsch N,Cox A,Reeder R,Carruthers S,Hall A,Stemple DL,Grainger RM, Dev Biol. November 15, 2014; 395(2):1095-564X.

The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice., Lieu T,Jayaweera G,Zhao P,Poole DP,Jensen D,Grace M,McIntyre P,Bron R,Wilson YM,Krappitz M,Haerteis S,Korbmacher C,Steinhoff MS,Nassini R,Materazzi S,Geppetti P,Corvera CU,Bunnett NW, Gastroenterology. December 1, 2014; 147(6):1528-0012.

Cloning, functional characterization, and remodeling of K2P3.1 (TASK-1) potassium channels in a porcine model of atrial fibrillation and heart failure., Schmidt C,Wiedmann F,Langer C,Tristram F,Anand P,Wenzel W,Lugenbiel P,Schweizer PA,Katus HA,Thomas D, Heart Rhythm. October 1, 2014; 11(10):1547-5271.

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Stoichiometry and specific assembly of Best ion channels., Bharill S,Fu Z,Palty R,Isacoff EY, Proc Natl Acad Sci U S A. April 29, 2014; 111(17):1091-6490.

A missense mutation accelerating the gating of the lysosomal Cl-/H+-exchanger ClC-7/Ostm1 causes osteopetrosis with gingival hamartomas in cattle., Sartelet A,Stauber T,Coppieters W,Ludwig CF,Fasquelle C,Druet T,Zhang Z,Zhang Z,Zhang Z,Ahariz N,Cambisano N,Jentsch TJ,Charlier C, Dis Model Mech. January 1, 2014; 7(1):1754-8411.

A Gro/TLE-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression., Kaltenbrun E,Greco TM,Slagle CE,Kennedy LM,Li T,Cristea IM,Conlon FL, J Proteome Res. December 6, 2013; 12(12):1535-3907.

The cataract and glucosuria associated monocarboxylate transporter MCT12 is a new creatine transporter., Abplanalp J,Laczko E,Philp NJ,Neidhardt J,Zuercher J,Braun P,Schorderet DF,Munier FL,Verrey F,Berger W,Camargo SM,Kloeckener-Gruissem B, Hum Mol Genet. August 15, 2013; 22(16):1460-2083.

Distinct patterns of compartmentalization and proteolytic stability of PDE6C mutants linked to achromatopsia., Cheguru P,Majumder A,Artemyev NO, Mol Cell Neurosci. January 1, 2015; 64:1044-7431.

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A functional correlate of severity in alternating hemiplegia of childhood., Li M,Jazayeri D,Corry B,McSweeney KM,Heinzen EL,Goldstein DB,Petrou S, Neurobiol Dis. May 1, 2015; 77:1095-953X.

A recurrent de novo mutation in KCNC1 causes progressive myoclonus epilepsy., Muona M,Berkovic SF,Dibbens LM,Oliver KL,Maljevic S,Bayly MA,Joensuu T,Canafoglia L,Franceschetti S,Michelucci R,Markkinen S,Heron SE,Hildebrand MS,Andermann E,Andermann F,Gambardella A,Tinuper P,Licchetta L,Scheffer IE,Criscuolo C,Filla A,Ferlazzo E,Ahmad J,Ahmad A,Baykan B,Said E,Topcu M,Riguzzi P,King MD,Ozkara C,Andrade DM,Engelsen BA,Crespel A,Lindenau M,Lohmann E,Saletti V,Massano J,Privitera M,Espay AJ,Kauffmann B,Duchowny M,Møller RS,Straussberg R,Afawi Z,Ben-Zeev B,Samocha KE,Daly MJ,Petrou S,Lerche H,Palotie A,Lehesjoki AE, Nat Genet. January 1, 2015; 47(1):1546-1718.

TASK-1 and TASK-3 may form heterodimers in human atrial cardiomyocytes., Rinné S,Kiper AK,Schlichthörl G,Dittmann S,Netter MF,Limberg SH,Silbernagel N,Zuzarte M,Moosdorf R,Wulf H,Schulze-Bahr E,Rolfes C,Decher N, J Mol Cell Cardiol. April 1, 2015; 81:1095-8584.

Loss of functional endothelial connexin40 results in exercise-induced hypertension in mice., Morton SK,Chaston DJ,Howitt L,Heisler J,Nicholson BJ,Fairweather S,Bröer S,Ashton AW,Matthaei KI,Hill CE, Hypertension. March 1, 2015; 65(3):1524-4563.

Using Xenopus tissue cultures for the study of myasthenia gravis pathogenesis., Yeo HL,Lim JY,Fukami Y,Yuki N,Lee CW,Lee CW,Lee CW, Dev Biol. December 15, 2015; 408(2):1095-564X.

More similar than you think: Frog metamorphosis as a model of human perinatal endocrinology., Buchholz DR, Dev Biol. December 15, 2015; 408(2):1095-564X.

Derricin and derricidin inhibit Wnt/β-catenin signaling and suppress colon cancer cell growth in vitro., Fonseca BF,Predes D,Cerqueira DM,Reis AH,Amado NG,Cayres MC,Kuster RM,Oliveira FL,Mendes FA,Abreu JG, PLoS One. March 16, 2015; 10(3):1932-6203.

Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma., Wylie LA,Hardwick LJ,Papkovskaia TD,Thiele CJ,Philpott A, Dis Model Mech. May 1, 2015; 8(5):1754-8411.

Osmostress-induced apoptosis in Xenopus oocytes: role of stress protein kinases, calpains and Smac/DIABLO., Ben Messaoud N,Yue J,Valent D,Katzarova I,López JM, PLoS One. January 1, 2015; 10(4):1932-6203.

ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia., Walentek P,Beyer T,Hagenlocher C,Müller C,Feistel K,Schweickert A,Harland RM,Blum M, Dev Biol. December 15, 2015; 408(2):1095-564X.

Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients., Nakayama T,Fisher M,Fisher M,Nakajima K,Odeleye AO,Zimmerman KB,Zimmerman KB,Fish MB,Yaoita Y,Chojnowski JL,Lauderdale JD,Netland PA,Grainger RM, Dev Biol. December 15, 2015; 408(2):1095-564X.

Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model., Pfirrmann T,Emmerich D,Ruokonen P,Quandt D,Buchen R,Fischer-Zirnsak B,Hecht J,Krawitz P,Meyer P,Klopocki E,Stricker S,Lausch E,Seliger B,Hollemann T,Reinhard T,Auw-Haedrich C,Zabel B,Hoffmann K,Villavicencio-Lorini P, Hum Mol Genet. June 1, 2015; 24(11):1460-2083.

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy., Raymond A,Liu B,Liang H,Wei C,Guindani M,Lu Y,Liang S,St John LS,Molldrem J,Nagarajan L, Oncotarget. December 30, 2014; 5(24):1949-2553.

Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3., McCormick JA,Yang CL,Zhang C,Davidge B,Blankenstein KI,Terker AS,Yarbrough B,Meermeier NP,Park HJ,McCully B,West M,Borschewski A,Himmerkus N,Bleich M,Bachmann S,Mutig K,Argaiz ER,Gamba G,Singer JD,Ellison DH, J Clin Invest. November 1, 2014; 124(11):1558-8238.

Nav1.1 modulation by a novel triazole compound attenuates epileptic seizures in rodents., Gilchrist J,Dutton S,Diaz-Bustamante M,McPherson A,Olivares N,Kalia J,Escayg A,Bosmans F, ACS Chem Biol. May 16, 2014; 9(5):1554-8937.

Mutating a conserved proline residue within the trimerization domain modifies Na+ binding to excitatory amino acid transporters and associated conformational changes., Hotzy J,Schneider N,Kovermann P,Fahlke C, J Biol Chem. December 20, 2013; 288(51):1083-351X.

Remyelination by Resident Oligodendrocyte Precursor Cells in a Xenopus laevis Inducible Model of Demyelination., Sekizar S,Mannioui A,Azoyan L,Colin C,Thomas JL,Du Pasquier D,Mallat M,Zalc B, Dev Neurosci. January 1, 2015; 37(3):1421-9859.

The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception., Nagy V,Cole T,Van Campenhout C,Khoung TM,Leung C,Vermeiren S,Novatchkova M,Wenzel D,Cikes D,Polyansky AA,Kozieradzki I,Meixner A,Bellefroid EJ,Neely GG,Penninger JM, Cell Cycle. January 1, 2015; 14(12):1551-4005.

Genetically induced dysfunctions of Kir2.1 channels: implications for short QT3 syndrome and autism-epilepsy phenotype., Ambrosini E,Sicca F,Brignone MS,D'Adamo MC,Napolitano C,Servettini I,Moro F,Ruan Y,Guglielmi L,Pieroni S,Servillo G,Lanciotti A,Valvo G,Catacuzzeno L,Franciolini F,Molinari P,Marchese M,Grottesi A,Guerrini R,Santorelli FM,Priori S,Pessia M, Hum Mol Genet. September 15, 2014; 23(18):1460-2083.

Follicle Online: an integrated database of follicle assembly, development and ovulation., Hua J,Xu B,Yang Y,Yang Y,Ban R,Iqbal F,Cooke HJ,Zhang Y,Zhang Y,Shi Q, Database (Oxford). April 29, 2015; 2015:1758-0463.

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Regulation of the Rev1-pol ζ complex during bypass of a DNA interstrand cross-link., Budzowska M,Graham TG,Sobeck A,Waga S,Walter JC, EMBO J. July 14, 2015; 34(14):0261-4189.

High incidence of functional ion-channel abnormalities in a consecutive Long QT cohort with novel missense genetic variants of unknown significance., Steffensen AB,Refaat MM,David JP,Mujezinovic A,Calloe K,Wojciak J,Nussbaum RL,Scheinman MM,Schmitt N, Sci Rep. January 12, 2015; 5:2045-2322.

TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis., Van Nieuwenhuysen T,Naert T,Tran HT,Van Imschoot G,Geurs S,Sanders E,Creytens D,Van Roy F,Vleminckx K,Vleminckx K, Oncoscience. May 19, 2015; 2(5):2331-4737.

9B.03: A NOVEL INSERTIONAL SOMATIC KCNJ5 MUTATION IN AN AUSTRALIAN PATIENT WITH AN ALDOSTERONE PRODUCING ADENOMA., Xu S,Hardege I,Murthy M,Gordon R,Stowasser M,OʼShaughnessy K, J Hypertens. June 1, 2015; 33 Suppl 1:1473-5598.

PnPP-19, a Synthetic and Nontoxic Peptide Designed from a Phoneutria nigriventer Toxin, Potentiates Erectile Function via NO/cGMP., Silva CN,Nunes KP,Torres FS,Cassoli JS,Santos DM,Almeida Fde M,Matavel A,Cruz JS,Santos-Miranda A,Nunes AD,Castro CH,Machado de Ávila RA,Chávez-Olórtegui C,Láuar SS,Felicori L,Resende JM,Camargos ER,Borges MH,Cordeiro MN,Peigneur S,Tytgat J,de Lima ME, J Urol. November 1, 2015; 194(5):1527-3792.

Molecular asymmetry in the 8-cell stage Xenopus tropicalis embryo described by single blastomere transcript sequencing., De Domenico E,Owens ND,Grant IM,Gomes-Faria R,Gilchrist MJ, Dev Biol. December 15, 2015; 408(2):1095-564X.

The UNC-45 myosin chaperone: from worms to flies to vertebrates., Lee CF,Lee CF,Lee CF,Melkani GC,Bernstein SI, Int Rev Cell Mol Biol. January 1, 2014; 313:1937-6448.

GABAA currents are decreased by IL-1β in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis., Roseti C,van Vliet EA,Cifelli P,Ruffolo G,Baayen JC,Di Castro MA,Bertollini C,Limatola C,Aronica E,Vezzani A,Palma E, Neurobiol Dis. October 1, 2015; 82:1095-953X.

ADAM13 cleavage of cadherin-11 promotes CNC migration independently of the homophilic binding site., Abbruzzese G,Becker SF,Kashef J,Alfandari D,Alfandari D, Dev Biol. July 15, 2016; 415(2):1095-564X.

The N-methyl-D-aspartate receptor's neglected subunit - GluN1 matters under normal and hyperbaric conditions., Bliznyuk A,Aviner B,Golan H,Hollmann M,Grossman Y, Eur J Neurosci. October 1, 2015; 42(8):1460-9568.

Novel BCOR mutation in a boy with Lenz microphthalmia/oculo-facio-cardio-dental (OFCD) syndrome., Zhu X,Dai FR,Wang J,Zhang Y,Zhang Y,Tan ZP,Zhang Y,Zhang Y, Gene. October 15, 2015; 571(1):1879-0038.

Huntingtin is required for ciliogenesis and neurogenesis during early Xenopus development., Haremaki T,Deglincerti A,Brivanlou AH, Dev Biol. December 15, 2015; 408(2):1095-564X.

Human slack potassium channel mutations increase positive cooperativity between individual channels., Kim GE,Kronengold J,Barcia G,Quraishi IH,Martin HC,Blair E,Taylor JC,Dulac O,Colleaux L,Nabbout R,Kaczmarek LK, Cell Rep. December 11, 2014; 9(5):2211-1247.

A Disease Mutation Causing Episodic Ataxia Type I in the S1 Links Directly to the Voltage Sensor and the Selectivity Filter in Kv Channels., Petitjean D,Kalstrup T,Zhao J,Blunck R, J Neurosci. September 2, 2015; 35(35):1529-2401.

Analyzing and Modeling the Kinetics of Amyloid Beta Pores Associated with Alzheimer's Disease Pathology., Ullah G,Demuro A,Parker I,Pearson JE, PLoS One. September 4, 2015; 10(9):1932-6203.

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Amyloid pore-channel hypothesis: effect of ethanol on aggregation state using frog oocytes for an Alzheimer's disease study., Parodi J,Ormeño D,Ochoa-de la Paz LD, BMB Rep. January 1, 2015; 48(1):1976-670X.

Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes., Lemke JR,Lal D,Reinthaler EM,Steiner I,Nothnagel M,Alber M,Geider K,Laube B,Schwake M,Finsterwalder K,Franke A,Schilhabel M,Jähn JA,Muhle H,Boor R,Van Paesschen W,Caraballo R,Fejerman N,Weckhuysen S,De Jonghe P,Larsen J,Møller RS,Hjalgrim H,Addis L,Tang S,Hughes E,Pal DK,Veri K,Vaher U,Talvik T,Dimova P,Guerrero López R,Serratosa JM,Linnankivi T,Lehesjoki AE,Ruf S,Wolff M,Buerki S,Wohlrab G,Kroell J,Datta AN,Fiedler B,Kurlemann G,Kluger G,Hahn A,Haberlandt DE,Kutzer C,Sperner J,Becker F,Weber YG,Feucht M,Steinböck H,Neophythou B,Ronen GM,Gruber-Sedlmayr U,Geldner J,Harvey RJ,Hoffmann P,Herms S,Altmüller J,Toliat MR,Thiele H,Nürnberg P,Wilhelm C,Stephani U,Helbig I,Lerche H,Zimprich F,Neubauer BA,Biskup S,von Spiczak S, Nat Genet. September 1, 2013; 45(9):1546-1718.

Xenopus laevis as a Model to Identify Translation Impairment., de Broucker A,Semaille P,Cailliau K,Martoriati A,Comptdaer T,Bodart JF,Destée A,Chartier-Harlin MC, J Vis Exp. September 27, 2015; (103):1940-087X.

Activation of TRPV1 channels inhibits mechanosensitive Piezo channel activity by depleting membrane phosphoinositides., Borbiro I,Badheka D,Rohacs T, Sci Signal. February 10, 2015; 8(363):1937-9145.

The NIMA-like kinase Nek2 is a key switch balancing cilia biogenesis and resorption in the development of left-right asymmetry., Endicott SJ,Basu B,Khokha M,Brueckner M, Development. December 1, 2015; 142(23):1477-9129.

Identification and Functional Characterization of CLCN1 Mutations Found in Nondystrophic Myotonia Patients., Vindas-Smith R,Fiore M,Vásquez M,Cuenca P,Del Valle G,Lagostena L,Gaitán-Peñas H,Estevez R,Pusch M,Morales F, Hum Mutat. January 1, 2016; 37(1):1098-1004.

A channelopathy mechanism revealed by direct calmodulin activation of TrpV4., Loukin SH,Teng J,Kung C, Proc Natl Acad Sci U S A. July 28, 2015; 112(30):1091-6490.

CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus., Bhattacharya D,Marfo CA,Li D,Lane M,Khokha MK, Dev Biol. December 15, 2015; 408(2):1095-564X.

Ptbp1 and Exosc9 knockdowns trigger skin stability defects through different pathways., Noiret M,Mottier S,Angrand G,Gautier-Courteille C,Lerivray H,Viet J,Paillard L,Mereau A,Hardy S,Audic Y, Dev Biol. January 15, 2016; 409(2):1095-564X.

Deletions and de novo mutations of SOX11 are associated with a neurodevelopmental disorder with features of Coffin-Siris syndrome., Hempel A,Pagnamenta AT,Blyth M,Mansour S,McConnell V,Kou I,Ikegawa S,Tsurusaki Y,Matsumoto N,Lo-Castro A,Plessis G,Albrecht B,Battaglia A,Taylor JC,Howard MF,Keays D,Sohal AS,Kühl SJ,Kühl SJ,Kini U,McNeill A, J Med Genet. March 1, 2016; 53(3):1468-6244.

Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of left-right asymmetry., Silva E,Betleja E,John E,Spear P,Moresco JJ,Zhang S,Yates JR,Mitchell BJ,Mahjoub MR, Mol Biol Cell. January 1, 2016; 27(1):1939-4586.

The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride., Bazúa-Valenti S,Chávez-Canales M,Rojas-Vega L,González-Rodríguez X,Vázquez N,Rodríguez-Gama A,Argaiz ER,Melo Z,Plata C,Ellison DH,García-Valdés J,Hadchouel J,Gamba G, J Am Soc Nephrol. August 1, 2015; 26(8):1533-3450.

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Distinctive effects of nicotinic receptor intracellular-loop mutations associated with nocturnal frontal lobe epilepsy., Weltzin MM,Lindstrom JM,Lukas RJ,Whiteaker P, Neuropharmacology. March 1, 2016; 102:1873-7064.

Alternative splice variant of the thiazide-sensitive NaCl cotransporter: a novel player in renal salt handling., Tutakhel OA,Jeleń S,Valdez-Flores M,Dimke H,Piersma SR,Jimenez CR,Deinum J,Lenders JW,Hoenderop JG,Bindels RJ, Am J Physiol Renal Physiol. February 1, 2016; 310(3):1522-1466.

RNA-Seq and microarray analysis of the Xenopus inner ear transcriptome discloses orthologous OMIM(®) genes for hereditary disorders of hearing and balance., Ramírez-Gordillo D,Powers TR,van Velkinburgh JC,Trujillo-Provencio C,Schilkey F,Serrano EE, BMC Res Notes. November 18, 2015; 8:1756-0500.

Using Xenopus to study genetic kidney diseases., Lienkamp SS, Semin Cell Dev Biol. March 1, 2016; 51:1096-3634.

Sf3b4-depleted Xenopus embryos: A model to study the pathogenesis of craniofacial defects in Nager syndrome., Devotta A,Juraver-Geslin H,Gonzalez JA,Hong CS,Saint-Jeannet JP, Dev Biol. July 15, 2016; 415(2):1095-564X.

Iron Overload Leading to Torsades de Pointes in β-Thalassemia and Long QT Syndrome., Refaat MM,El Hage L,Steffensen AB,Hotait M,Schmitt N,Scheinman M,Badhwar N, Card Electrophysiol Clin. March 1, 2016; 8(1):1877-9190.

Polyunsaturated fatty acids are potent openers of human M-channels expressed in Xenopus laevis oocytes., Liin SI,Karlsson U,Bentzen BH,Schmitt N,Elinder F, Acta Physiol (Oxf). September 1, 2016; 218(1):1748-1716.

Xenopus as a model organism for birth defects-Congenital heart disease and heterotaxy., Duncan AR,Khokha MK, Semin Cell Dev Biol. March 1, 2016; 51:1096-3634.

Acetylcholine receptors from human muscle as pharmacological targets for ALS therapy., Palma E,Reyes-Ruiz JM,Lopergolo D,Roseti C,Bertollini C,Ruffolo G,Cifelli P,Onesti E,Limatola C,Miledi R,Inghilleri M, Proc Natl Acad Sci U S A. March 15, 2016; 113(11):1091-6490.

A pure chloride channel mutant of CLC-5 causes Dent's disease via insufficient V-ATPase activation., Satoh N,Yamada H,Yamazaki O,Suzuki M,Suzuki M,Nakamura M,Suzuki A,Ashida A,Yamamoto D,Kaku Y,Sekine T,Seki G,Horita S, Pflugers Arch. July 1, 2016; 468(7):1432-2013.

Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin., Gouignard N,Maccarana M,Strate I,von Stedingk K,Malmström A,Pera EM, Dis Model Mech. June 1, 2016; 9(6):1754-8411.

The search for NKCC1-selective drugs for the treatment of epilepsy: Structure-function relationship of bumetanide and various bumetanide derivatives in inhibiting the human cation-chloride cotransporter NKCC1A., Lykke K,Töllner K,Feit PW,Erker T,MacAulay N,Löscher W, Epilepsy Behav. June 1, 2016; 59:1525-5069.

The cataract related mutation N188T in human connexin46 (hCx46) revealed a critical role for residue N188 in the docking process of gap junction channels., Schadzek P,Schlingmann B,Schaarschmidt F,Lindner J,Koval M,Heisterkamp A,Preller M,Ngezahayo A, Biochim Biophys Acta. January 1, 2016; 1858(1):0006-3002.

WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis., Nalesso G,Thomas BL,Sherwood JC,Yu J,Addimanda O,Eldridge SE,Thorup AS,Dale L,Schett G,Zwerina J,Eltawil N,Pitzalis C,Dell'Accio F, Ann Rheum Dis. January 1, 2017; 76(1):1468-2060.

Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer., Puvirajesinghe TM,Bertucci F,Jain A,Scerbo P,Belotti E,Audebert S,Sebbagh M,Lopez M,Brech A,Finetti P,Charafe-Jauffret E,Chaffanet M,Castellano R,Restouin A,Marchetto S,Collette Y,Gonçalvès A,Macara I,Birnbaum D,Kodjabachian L,Johansen T,Borg JP, Nat Commun. January 12, 2016; 7:2041-1723.

Immunosuppressive evidence of Tityus serrulatus toxins Ts6 and Ts15: insights of a novel K(+) channel pattern in T cells., Pucca MB,Bertolini TB,Cerni FA,Bordon KC,Peigneur S,Tytgat J,Bonato VL,Arantes EC, Immunology. February 1, 2016; 147(2):1365-2567.

A novel mutant Na + /HCO3 - cotransporter NBCe1 in a case of compound-heterozygous inheritance of proximal renal tubular acidosis., Myers EJ,Yuan L,Felmlee MA,Lin YY,Jiang Y,Pei Y,Wang O,Li M,Xing XP,Marshall A,Xia WB,Parker MD, J Physiol. November 1, 2016; 594(21):0022-3751.

A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification., Rankin SA,Rankin SA,Han L,McCracken KW,Kenny AP,Anglin CT,Grigg EA,Crawford CM,Wells JM,Shannon JM,Zorn AM, Cell Rep. June 28, 2016; 16(1):2211-1247.

ROMK expression remains unaltered in a mouse model of familial hyperkalemic hypertension caused by the CUL3Δ403-459 mutation., Murthy M,Kurz T,O'Shaughnessy KM, Physiol Rep. July 1, 2016; 4(13):2051-817X.

Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy., Sicca F,Ambrosini E,Marchese M,Sforna L,Servettini I,Valvo G,Brignone MS,Lanciotti A,Moro F,Grottesi A,Catacuzzeno L,Baldini S,Hasan S,D'Adamo MC,Franciolini F,Molinari P,Santorelli FM,Pessia M, Sci Rep. September 28, 2016; 6:2045-2322.

Functional Recovery of AQP2 Recessive Mutations Through Hetero-Oligomerization with Wild-Type Counterpart., El Tarazi A,Lussier Y,Da Cal S,Bissonnette P,Bichet DG, Sci Rep. September 19, 2016; 6:2045-2322.

Determining the optimal developmental stages of Xenopus laevis for initiating exposures to chemicals for sensitively detecting their feminizing effects on gonadal differentiation., Li YY,Chen J,Qin ZF, Aquat Toxicol. October 1, 2016; 179:1879-1514.

Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia., Del Viso F,Huang F,Myers J,Chalfant M,Zhang Y,Zhang Y,Reza N,Bewersdorf J,Lusk CP,Khokha MK, Dev Cell. September 12, 2016; 38(5):1878-1551.

The Enigma of the Dichotomic Pressure Response of GluN1-4a/b Splice Variants of NMDA Receptor: Experimental and Statistical Analyses., Bliznyuk A,Gradwohl G,Hollmann M,Grossman Y, Front Mol Neurosci. February 15, 2016; 9:1662-5099.

Mutation Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Reduces Low-Sensitivity α4β2, and Increases α5α4β2, Nicotinic Receptor Surface Expression., Nichols WA,Henderson BJ,Marotta CB,Yu CY,Richards C,Dougherty DA,Lester HA,Cohen BN, PLoS One. January 1, 2016; 11(6):1932-6203.

CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis., Naert T,Colpaert R,Van Nieuwenhuysen T,Dimitrakopoulou D,Leoen J,Haustraete J,Boel A,Steyaert W,Lepez T,Deforce D,Willaert A,Creytens D,Vleminckx K,Vleminckx K, Sci Rep. October 14, 2016; 6:2045-2322.

Expression of ribosomopathy genes during Xenopus tropicalis embryogenesis., Robson A,Owens ND,Baserga SJ,Khokha MK,Griffin JN, BMC Dev Biol. October 26, 2016; 16(1):1471-213X.

Novel KCNQ3 Mutation in a Large Family with Benign Familial Neonatal Epilepsy: A Rare Cause of Neonatal Seizures., Maljevic S,Vejzovic S,Bernhard MK,Bertsche A,Weise S,Döcker M,Lerche H,Lemke JR,Merkenschlager A,Syrbe S, Mol Syndromol. September 1, 2016; 7(4):1661-8769.

Copy number variation as a genetic basis for heterotaxy and heterotaxy-spectrum congenital heart defects., Cowan JR,Tariq M,Shaw C,Rao M,Belmont JW,Lalani SR,Smolarek TA,Ware SM, Philos Trans R Soc Lond B Biol Sci. December 19, 2016; 371(1710):1471-2970.

Functional assessment of SLC4A11, an integral membrane protein mutated in corneal dystrophies., Loganathan SK,Schneider HP,Morgan PE,Deitmer JW,Casey JR, Am J Physiol Cell Physiol. November 1, 2016; 311(5):1522-1563.

Sox9 function in craniofacial development and disease., Lee YH,Lee YH,Saint-Jeannet JP, Genesis. April 1, 2011; 49(4):1526-968X.

Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)., Tristani-Firouzi M,Jensen JL,Donaldson MR,Sansone V,Meola G,Hahn A,Bendahhou S,Kwiecinski H,Fidzianska A,Plaster N,Fu YH,Ptacek LJ,Tawil R, J Clin Invest. August 1, 2002; 110(3):1558-8238.

An Epha4/Sipa1l3/Wnt pathway regulates eye development and lens maturation., Rothe M,Kanwal N,Dietmann P,Seigfried FA,Hempel A,Schütz D,Reim D,Engels R,Linnemann A,Schmeisser MJ,Bockmann J,Kühl M,Boeckers TM,Kühl SJ, Development. January 15, 2017; 144(2):1477-9129.

Association between Single-Nucleotide Polymorphisms of the hOGG1,NEIL1,APEX1, FEN1,LIG1, and LIG3 Genes and Alzheimer's Disease Risk., Kwiatkowski D,Czarny P,Toma M,Korycinska A,Sowinska K,Galecki P,Bachurska A,Bielecka-Kowalska A,Szemraj J,Maes M,Sliwinski T, Neuropsychobiology. January 1, 2016; 73(2):1423-0224.

Mutations in GABRB3: From febrile seizures to epileptic encephalopathies., Møller RS,Wuttke TV,Helbig I,Marini C,Johannesen KM,Brilstra EH,Vaher U,Borggraefe I,Talvik I,Talvik T,Kluger G,Francois LL,Lesca G,de Bellescize J,Blichfeldt S,Chatron N,Holert N,Jacobs J,Swinkels M,Betzler C,Syrbe S,Nikanorova M,Myers CT,Larsen LH,Vejzovic S,Pendziwiat M,von Spiczak S,Hopkins S,Dubbs H,Mang Y,Mukhin K,Holthausen H,van Gassen KL,Dahl HA,Tommerup N,Mefford HC,Rubboli G,Guerrini R,Lemke JR,Lerche H,Muhle H,Maljevic S, Neurology. January 31, 2017; 88(5):1526-632X.

TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models., Naert T,Van Nieuwenhuysen T,Vleminckx K,Vleminckx K, Genesis. January 1, 2017; 55(1-2):1526-968X.

Opposing Effects of Valproic Acid Treatment Mediated by Histone Deacetylase Inhibitor Activity in Four Transgenic X. laevis Models of Retinitis Pigmentosa., Vent-Schmidt RYJ,Wen RH,Zong Z,Chiu CN,Tam BM,May CG,Moritz OL, J Neurosci. January 25, 2017; 37(4):1529-2401.

Using Xenopus to understand human disease and developmental disorders., Sater AK,Moody SA, Genesis. January 1, 2017; 55(1-2):1526-968X.

Modeling human craniofacial disorders in Xenopus., Dubey A,Saint-Jeannet JP, Curr Pathobiol Rep. March 1, 2017; 5(1):2167-485X.

A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction., Stallmeyer B,Kuß J,Kotthoff S,Zumhagen S,Vowinkel K,Rinné S,Matschke LA,Friedrich C,Schulze-Bahr E,Rust S,Seebohm G,Decher N,Schulze-Bahr E, Circ Res. May 12, 2017; 120(10):1524-4571.

Analysis of Craniocardiac Malformations in Xenopus using Optical Coherence Tomography., Deniz E,Jonas S,Hooper M,N Griffin J,Choma MA,Khokha MK, Sci Rep. February 14, 2017; 7:2045-2322.

Toolbox in a tadpole: Xenopus for kidney research., Getwan M,Lienkamp SS, Cell Tissue Res. July 1, 2017; 369(1):1432-0878.

Clinical and Genetic Spectrum of Bartter Syndrome Type 3., Seys E,Andrini O,Keck M,Mansour-Hendili L,Courand PY,Simian C,Deschenes G,Kwon T,Bertholet-Thomas A,Bobrie G,Borde JS,Bourdat-Michel G,Decramer S,Cailliez M,Krug P,Cozette P,Delbet JD,Dubourg L,Chaveau D,Fila M,Jourde-Chiche N,Knebelmann B,Lavocat MP,Lemoine S,Djeddi D,Llanas B,Louillet F,Merieau E,Mileva M,Mota-Vieira L,Mousson C,Nobili F,Novo R,Roussey-Kesler G,Vrillon I,Walsh SB,Teulon J,Blanchard A,Vargas-Poussou R, J Am Soc Nephrol. August 1, 2017; 28(8):1533-3450.

A Dominant Mutation in Nuclear Receptor Interacting Protein 1 Causes Urinary Tract Malformations via Dysregulation of Retinoic Acid Signaling., Vivante A,Mann N,Yonath H,Weiss AC,Getwan M,Kaminski MM,Bohnenpoll T,Teyssier C,Chen J,Shril S,van der Ven AT,Ityel H,Schmidt JM,Widmeier E,Bauer SB,Sanna-Cherchi S,Gharavi AG,Lu W,Magen D,Shukrun R,Lifton RP,Tasic V,Stanescu HC,Cavaillès V,Kleta R,Anikster Y,Dekel B,Kispert A,Lienkamp SS,Hildebrandt F, J Am Soc Nephrol. August 1, 2017; 28(8):1533-3450.

Mechanosensory Stimulation Evokes Acute Concussion-Like Behavior by Activating GIRKs Coupled to Muscarinic Receptors in a Simple Vertebrate., Li WC,Zhu XY,Ritson E, eNeuro. January 1, 2017; 4(2):2373-2822.

Co-accumulation of cis-regulatory and coding mutations during the pseudogenization of the Xenopus laevis homoeologs six6.L and six6.S., Ochi H,Kawaguchi A,Tanouchi M,Suzuki N,Kumada T,Iwata Y,Ogino H, Dev Biol. July 1, 2017; 427(1):1095-564X.

Mouth development., Chen J,Jacox LA,Saldanha F,Sive H, Wiley Interdiscip Rev Dev Biol. September 1, 2017; 6(5):1759-7692.

Aberrant regulation of Wnt signaling in hepatocellular carcinoma., Liu LJ,Xie SX,Chen YT,Chen YT,Xue JL,Zhang CJ,Zhu F, World J Gastroenterol. September 7, 2016; 22(33):2219-2840.

Bacterial Sphingomyelinase is a State-Dependent Inhibitor of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR)., Stauffer BB,Cui G,Cottrill KA,Infield DT,McCarty NA, Sci Rep. June 7, 2017; 7(1):2045-2322.

Modeling Dominant and Recessive Forms of Retinitis Pigmentosa by Editing Three Rhodopsin-Encoding Genes in Xenopus Laevis Using Crispr/Cas9., Feehan JM,Chiu CN,Stanar P,Tam BM,Ahmed SN,Moritz OL, Sci Rep. July 31, 2017; 7(1):2045-2322.

TPX2-p53-GLIPR1 regulatory circuitry in cell proliferation, invasion, and tumor growth of bladder cancer., Yan L,Li Q,Yang J,Qiao B, J Cell Biochem. February 1, 2018; 119(2):0730-2312.

The L530R variation associated with recurrent kidney stones impairs the structure and function of TRPV5., Wang L,Holmes RP,Peng JB, Biochem Biophys Res Commun. October 21, 2017; 492(3):1090-2104.

Antidepressant, anticonvulsant and antinociceptive effects of 3'-methoxy-6-methylflavone and 3'-hydroxy-6-methylflavone may involve GABAergic mechanisms., Karim N,Khan I,Ahmad N,Umar MN,Gavande N, Pharmacol Rep. October 1, 2017; 69(5):1734-1140.

The Xenopus tadpole: An in vivo model to screen drugs favoring remyelination., Mannioui A,Vauzanges Q,Fini JB,Henriet E,Sekizar S,Azoyan L,Thomas JL,Pasquier DD,Giovannangeli C,Demeneix B,Lubetzki C,Zalc B, Mult Scler. October 1, 2018; 24(11):1477-0970.

The SLC2A14 gene, encoding the novel glucose/dehydroascorbate transporter GLUT14, is associated with inflammatory bowel disease., Amir Shaghaghi M,Zhouyao H,Tu H,El-Gabalawy H,Crow GH,Levine M,Bernstein CN,Eck P, Am J Clin Nutr. December 1, 2017; 106(6):0002-9165.

The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery., Toriyama M,Lee C,Lee C,Lee C,Taylor SP,Duran I,Cohn DH,Bruel AL,Tabler JM,Drew K,Kelly MR,Kim S,Park TJ,Braun DA,Pierquin G,Biver A,Wagner K,Malfroot A,Panigrahi I,Franco B,Al-Lami HA,Yeung Y,Choi YJ,Duffourd Y,Faivre L,Rivière JB,Chen J,Liu KJ,Liu KJ,Marcotte EM,Hildebrandt F,Thauvin-Robinet C,Krakow D,Jackson PK,Wallingford JB, Nat Genet. June 1, 2016; 48(6):1546-1718.

Fanconi-Anemia-Associated Mutations Destabilize RAD51 Filaments and Impair Replication Fork Protection., Zadorozhny K,Sannino V,Beláň O,Mlčoušková J,Špírek M,Costanzo V,Krejčí L, Cell Rep. October 10, 2017; 21(2):2211-1247.

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Kirsch N,Chang LS,Koch S,Glinka A,Dolde C,Colozza G,Benitez MDJ,De Robertis EM,Niehrs C, Dev Cell. October 9, 2017; 43(1):1878-1551.

Compound heterozygous alterations in intraflagellar transport protein CLUAP1 in a child with a novel Joubert and oral-facial-digital overlap syndrome., Johnston JJ,Lee C,Lee C,Lee C,Wentzensen IM,Parisi MA,Crenshaw MM,Sapp JC,Gross JM,Wallingford JB,Biesecker LG, Cold Spring Harb Mol Case Stud. July 1, 2017; 3(4):2373-2873.

The Sorting Nexin 3 Retromer Pathway Regulates the Cell Surface Localization and Activity of a Wnt-Activated Polycystin Channel Complex., Feng S,Streets AJ,Nesin V,Tran U,Nie H,Onopiuk M,Wessely O,Tsiokas L,Ong ACM, J Am Soc Nephrol. October 1, 2017; 28(10):1533-3450.

Development of GABAA Receptor Subtype-Selective Imidazobenzodiazepines as Novel Asthma Treatments., Forkuo GS,Guthrie ML,Yuan NY,Nieman AN,Kodali R,Jahan R,Stephen MR,Yocum GT,Treven M,Poe MM,Li G,Yu OB,Hartzler BD,Zahn NM,Ernst M,Emala CW,Stafford DC,Cook JM,Arnold LA, Mol Pharm. June 6, 2016; 13(6):1543-8392.

Rare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features., Niturad CE,Lev D,Kalscheuer VM,Charzewska A,Schubert J,Lerman-Sagie T,Kroes HY,Oegema R,Traverso M,Specchio N,Lassota M,Chelly J,Bennett-Back O,Carmi N,Koffler-Brill T,Iacomino M,Trivisano M,Capovilla G,Striano P,Nawara M,Rzonca S,Fischer U,Bienek M,Jensen C,Hu H,Thiele H,Altmüller J,Krause R,May P,Becker F,Balling R,Biskup S,Haas SA,Nürnberg P,van Gassen KLI,Lerche H,Zara F,Maljevic S,Leshinsky-Silver E, Brain. November 1, 2017; 140(11):1460-2156.

Clinical spectrum and genotype-phenotype associations of KCNA2-related encephalopathies., Masnada S,Hedrich UBS,Gardella E,Schubert J,Kaiwar C,Klee EW,Lanpher BC,Gavrilova RH,Synofzik M,Bast T,Gorman K,King MD,Allen NM,Conroy J,Ben Zeev B,Tzadok M,Korff C,Dubois F,Ramsey K,Narayanan V,Serratosa JM,Giraldez BG,Helbig I,Marsh E,O'Brien M,Bergqvist CA,Binelli A,Porter B,Zaeyen E,Horovitz DD,Wolff M,Marjanovic D,Caglayan HS,Arslan M,Pena SDJ,Sisodiya SM,Balestrini S,Syrbe S,Veggiotti P,Lemke JR,Møller RS,Lerche H,Rubboli G, Brain. September 1, 2017; 140(9):1460-2156.

A De Novo Mutation in the Sodium-Activated Potassium Channel KCNT2 Alters Ion Selectivity and Causes Epileptic Encephalopathy., Gururaj S,Palmer EE,Sheehan GD,Kandula T,Macintosh R,Ying K,Morris P,Tao J,Dias KR,Zhu Y,Dinger ME,Cowley MJ,Kirk EP,Roscioli T,Sachdev R,Duffey ME,Bye A,Bhattacharjee A, Cell Rep. October 24, 2017; 21(4):2211-1247.

Gain-of-function HCN2 variants in genetic epilepsy., Li M,Maljevic S,Phillips AM,Petrovski S,Hildebrand MS,Burgess R,Mount T,Zara F,Striano P,Schubert J,Thiele H,Nürnberg P,Wong M,Weisenberg JL,Thio LL,Lerche H,Scheffer IE,Berkovic SF,Petrou S,Reid CA, Hum Mutat. February 1, 2018; 39(2):1098-1004.

A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway., Salašová A,Yokota C,Potěšil D,Zdráhal Z,Bryja V,Arenas E, Mol Neurodegener. July 11, 2017; 12(1):1750-1326.

Abnormal creatine transport of mutations in monocarboxylate transporter 12 (MCT12) found in patients with age-related cataract can be partially rescued by exogenous chaperone CD147., Stäubli A,Capatina N,Fuhrer Y,Munier FL,Labs S,Schorderet DF,Tiwari A,Verrey F,Heon E,Cheng CY,Wong TY,Berger W,Camargo SMR,Kloeckener-Gruissem B, Hum Mol Genet. November 1, 2017; 26(21):1460-2083.

An interspecies heart-to-heart: Using Xenopus to uncover the genetic basis of congenital heart disease., Garfinkel AM,Khokha MK, Curr Pathobiol Rep. June 1, 2017; 5(2):2167-485X.

On the effect of hyperaldosteronism-inducing mutations in Na/K pumps., Meyer DJ,Gatto C,Artigas P, J Gen Physiol. November 6, 2017; 149(11):1540-7748.

Identification of Isthmin 1 as a Novel Clefting and Craniofacial Patterning Gene in Humans., Lansdon LA,Darbro BW,Petrin AL,Hulstrand AM,Standley JM,Brouillette RB,Long A,Mansilla MA,Cornell RA,Murray JC,Houston DW,Manak JR, Genetics. January 1, 2018; 208(1):1943-2631.

Clinical and molecular characterization of KCNT1-related severe early-onset epilepsy., McTague A,Nair U,Malhotra S,Meyer E,Trump N,Gazina EV,Papandreou A,Ngoh A,Ackermann S,Ambegaonkar G,Appleton R,Desurkar A,Eltze C,Kneen R,Kumar AV,Lascelles K,Montgomery T,Ramesh V,Samanta R,Scott RH,Tan J,Whitehouse W,Poduri A,Scheffer IE,Chong WKK,Cross JH,Topf M,Petrou S,Kurian MA, Neurology. January 2, 2018; 90(1):1526-632X.

Pro-arrhythmogenic Effects of the V141M KCNQ1 Mutation in Short QT Syndrome and Its Potential Therapeutic Targets: Insights from Modeling., Lee HC,Lee HC,Rudy Y,Liang H,Chen CC,Luo CH,Sheu SH,Cui J, J Med Biol Eng. October 1, 2017; 37(5):1609-0985.

Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis., Afouda BA,Lynch AT,de Paiva Alves E,Hoppler S, Dev Biol. February 1, 2018; 434(1):1095-564X.

Functional Reintegration of Sensory Neurons and Transitional Dendritic Reduction of Mitral/Tufted Cells during Injury-Induced Recovery of the Larval Xenopus Olfactory Circuit., Hawkins SJ,Weiss L,Offner T,Dittrich K,Hassenklöver T,Manzini I, Front Cell Neurosci. July 21, 2017; 11:1662-5102.

Anosmin-1 is essential for neural crest and cranial placodes formation in Xenopus., Bae CJ,Hong CS,Saint-Jeannet JP, Biochem Biophys Res Commun. January 15, 2018; 495(3):1090-2104.

Ketamine Modulates Zic5 Expression via the Notch Signaling Pathway in Neural Crest Induction., Shi Y,Shi Y,Li J,Chen C,Xia Y,Li Y,Zhang P,Xu Y,Xu Y,Li T,Zhou W,Song W, Front Mol Neurosci. February 7, 2018; 11:1662-5099.

Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney., Zhang B,Tran U,Wessely O, Development. March 22, 2018; 145(6):1477-9129.

Effects of trimethoprim-sulfadiazine and detomidine on the function of equine Kv 11.1 channels in a two-electrode voltage-clamp (TEVC) oocyte model., Trachsel DS,Tejada MA,Groesfjeld Christensen V,Pedersen PJ,Kanters JK,Buhl R,Calloe K,Klaerke DA, J Vet Pharmacol Ther. August 1, 2018; 41(4):1365-2885.

Targeted deletion of the aquaglyceroporin AQP9 is protective in a mouse model of Parkinson's disease., Stahl K,Rahmani S,Prydz A,Skauli N,MacAulay N,Mylonakou MN,Torp R,Skare Ø,Berg T,Leergaard TB,Paulsen RE,Ottersen OP,Amiry-Moghaddam M, PLoS One. January 1, 2018; 13(3):1932-6203.

Functional variants in HCN4 and CACNA1H may contribute to genetic generalized epilepsy., Becker F,Reid CA,Hallmann K,Tae HS,Phillips AM,Teodorescu G,Weber YG,Kleefuss-Lie A,Elger C,Perez-Reyes E,Petrou S,Kunz WS,Lerche H,Maljevic S, Epilepsia Open. August 5, 2017; 2(3):2470-9239.

Unexplained cardiac arrest: a tale of conflicting interpretations of KCNQ1 genetic test results., Chua HC,Servatius H,Asatryan B,Schaller A,Rieubland C,Noti F,Seiler J,Roten L,Baldinger SH,Tanner H,Fuhrer J,Haeberlin A,Lam A,Pless SA,Medeiros-Domingo A, Clin Res Cardiol. August 1, 2018; 107(8):1861-0692.

The Effects of 4-Hydroxybenzoic Acid Identified from Bamboo (Dendrocalamus asper) Shoots on Kv1.4 Channel., Zhang J,Mohamad FH,Wong JH,Mohamad H,Ismail AH,Mohamed Yusoff AA,Osman H,Wong KT,Idris Z,Abdullah JM, Malays J Med Sci. February 1, 2018; 25(1):1394-195X.

Identification of a cono-RFamide from the venom of Conus textile that targets ASIC3 and enhances muscle pain., Reimers C,Lee CH,Lee CH,Lee CH,Kalbacher H,Tian Y,Hung CH,Schmidt A,Prokop L,Kauferstein S,Mebs D,Chen CC,Gründer S, Proc Natl Acad Sci U S A. April 25, 2017; 114(17):1091-6490.

Unexpected metabolic disorders induced by endocrine disruptors in Xenopus tropicalis provide new lead for understanding amphibian decline., Regnault C,Usal M,Veyrenc S,Couturier K,Batandier C,Bulteau AL,Lejon D,Sapin A,Combourieu B,Chetiveaux M,Le May C,Lafond T,Raveton M,Reynaud S, Proc Natl Acad Sci U S A. May 8, 2018; 115(19):1091-6490.

FSHD2- and BAMS-associated mutations confer opposing effects on SMCHD1 function., Gurzau AD,Chen K,Xue S,Dai W,Lucet IS,Ly TTN,Reversade B,Blewitt ME,Murphy JM, J Biol Chem. June 22, 2018; 293(25):1083-351X.

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CRISPR/Cas9 F0 Screening of Congenital Heart Disease Genes in Xenopus tropicalis., Deniz E,Mis EK,Lane M,Khokha MK, Methods Mol Biol. January 1, 2018; 1865:1940-6029.

Lack of response to quinidine in KCNT1-related neonatal epilepsy., Numis AL,Nair U,Datta AN,Sands TT,Oldham MS,Patel A,Li M,Gazina E,Petrou S,Cilio MR, Epilepsia. October 1, 2018; 59(10):1528-1167.

Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome., Braun DA,Lovric S,Schapiro D,Schneider R,Marquez J,Asif M,Hussain MS,Daga A,Widmeier E,Rao J,Ashraf S,Tan W,Lusk CP,Kolb A,Jobst-Schwan T,Schmidt JM,Hoogstraten CA,Eddy K,Kitzler TM,Shril S,Moawia A,Schrage K,Khayyat AIA,Lawson JA,Gee HY,Warejko JK,Hermle T,Majmundar AJ,Hugo H,Budde B,Motameny S,Altmüller J,Noegel AA,Fathy HM,Gale DP,Waseem SS,Khan A,Kerecuk L,Hashmi S,Mohebbi N,Ettenger R,Serdaroğlu E,Alhasan KA,Hashem M,Goncalves S,Ariceta G,Ubetagoyena M,Antonin W,Baig SM,Alkuraya FS,Shen Q,Xu H,Antignac C,Lifton RP,Mane S,Nürnberg P,Khokha MK,Hildebrandt F, J Clin Invest. October 1, 2018; 128(10):1558-8238.

CRISPR/Cas9 disease models in zebrafish and Xenopus: The genetic renaissance of fish and frogs., Naert T,Vleminckx K,Vleminckx K, Drug Discov Today Technol. August 1, 2018; 28:1740-6749.

A review of interventions against fetal alcohol spectrum disorder targeting oxidative stress., Zhang Y,Zhang Y,Wang H,Li Y,Peng Y, Int J Dev Neurosci. December 1, 2018; 71:0736-5748.

WDR5 Stabilizes Actin Architecture to Promote Multiciliated Cell Formation., Kulkarni SS,Griffin JN,Date PP,Liem KF,Khokha MK, Dev Cell. September 10, 2018; 46(5):1878-1551.

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TPX2 level correlates with cholangiocarcinoma cell proliferation, apoptosis, and EMT., Zou Z,Zheng B,Li J,Lv X,Zhang H,Yu F,Kong L,Li Y,Yu M,Fang L,Liang B, Biomed Pharmacother. November 1, 2018; 107:0753-3322.

Paracetamol-induced liver injury modelled in Xenopus laevis embryos., Saide K,Sherwood V,Wheeler GN, Toxicol Lett. March 1, 2019; 302:1879-3169.

ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis., Song EK,Jeon J,Jang DG,Kim HE,Sim HJ,Kwon KY,Medina-Ruiz S,Jang HJ,Lee AR,Rho JG,Lee HS,Lee HS,Kim SJ,Park CY,Myung K,Kim W,Kwon T,Yang S,Park TJ, Sci Transl Med. October 10, 2018; 10(462):1946-6242.

A novel GABAergic dysfunction in human Dravet syndrome., Ruffolo G,Cifelli P,Roseti C,Thom M,van Vliet EA,Limatola C,Aronica E,Palma E, Epilepsia. November 1, 2018; 59(11):1528-1167.

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De novo pathogenic variants in neuronal differentiation factor 2 (NEUROD2) cause a form of early infantile epileptic encephalopathy., Sega AG,Mis EK,Lindstrom K,Mercimek-Andrews S,Ji W,Cho MT,Juusola J,Konstantino M,Jeffries L,Khokha MK,Lakhani SA, J Med Genet. February 1, 2019; 56(2):1468-6244.

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A novel autosomal recessive GJB2-associated disorder: Ichthyosis follicularis, bilateral severe sensorineural hearing loss, and punctate palmoplantar keratoderma., Youssefian L,Vahidnezhad H,Saeidian AH,Mahmoudi H,Karamzadeh R,Kariminejad A,Huang J,Li L,Jannace TF,Fortina P,Zeinali S,White TW,Uitto J, Hum Mutat. February 1, 2019; 40(2):1098-1004.

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Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability., Fu Z,Thorpe M,Akula S,Chahal G,Hellman LT, Front Immunol. September 12, 2018; 9:1664-3224.

Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer., Chen M,Zhang H,Zhang G,Zhong A,Ma Q,Kai J,Tong Y,Xie S,Wang Y,Zheng H,Guo L,Lu R, Biochem Biophys Res Commun. December 9, 2018; 507(1-4):1090-2104.

Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels., Zheng W,Yang X,Hu R,Cai R,Hofmann L,Wang Z,Hu Q,Liu X,Bulkley D,Yu Y,Tang J,Flockerzi V,Cao Y,Cao Y,Cao E,Chen XZ, Nat Commun. June 13, 2018; 9(1):2041-1723.

HCN2 Rescues brain defects by enforcing endogenous voltage pre-patterns., Pai VP,Pietak A,Willocq V,Ye B,Shi NQ,Levin M, Nat Commun. March 8, 2018; 9(1):2041-1723.

Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left-Right Organizer in Xenopus., Sempou E,Lakhani OA,Amalraj S,Khokha MK, Front Physiol. January 1, 2018; 9:1664-042X.

Xenopus tropicalis: Joining the Armada in the Fight Against Blood Cancer., Dimitrakopoulou D,Tulkens D,Van Vlierberghe P,Vleminckx K,Vleminckx K, Front Physiol. January 1, 2019; 10:1664-042X.

Myasthenic congenital myopathy from recessive mutations at a single residue in NaV1.4., Elia N,Palmio J,Castañeda MS,Shieh PB,Quinonez M,Suominen T,Hanna MG,Männikkö R,Udd B,Cannon SC, Neurology. March 26, 2019; 92(13):1526-632X.

Electrophysiological Changes During Early Steps of Retinitis Pigmentosa., Bocchero U,Tam BM,Chiu CN,Torre V,Moritz OL, Invest Ophthalmol Vis Sci. March 1, 2019; 60(4):1552-5783.

FoxN3 is necessary for the development of the interatrial septum, the ventricular trabeculae and the muscles at the head/trunk interface in the African clawed frog, Xenopus laevis (Lissamphibia: Anura: Pipidae)., Naumann B,Schmidt J,Olsson L, Dev Dyn. May 1, 2019; 248(5):1058-8388.

The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1., Ott T,Kaufmann L,Granzow M,Hinderhofer K,Bartram CR,Theiß S,Seitz A,Paramasivam N,Schulz A,Moog U,Blum M,Evers CM, Front Physiol. January 1, 2019; 10:1664-042X.

Structural basis of HEAT-kleisin interactions in the human condensin I subcomplex., Hara K,Kinoshita K,Migita T,Murakami K,Shimizu K,Takeuchi K,Hirano T,Hashimoto H, EMBO Rep. May 1, 2019; 20(5):1469-3178.

A de novo Ser111Thr variant in aquaporin-4 in a patient with intellectual disability, transient signs of brain ischemia, transient cardiac hypertrophy, and progressive gait disturbance., Berland S,Toft-Bertelsen TL,Aukrust I,Byska J,Vaudel M,Bindoff LA,MacAulay N,Houge G, Cold Spring Harb Mol Case Stud. February 1, 2018; 4(1):2373-2873.

Latrophilin2 is involved in neural crest cell migration and placode patterning in Xenopus laevis., Yokote N,Suzuki-Kosaka MY,Michiue T,Hara T,Tanegashima K, Int J Dev Biol. January 1, 2019; 63(1-2):1696-3547.

Desmoplakin is required for epidermal integrity and morphogenesis in the Xenopus laevis embryo., Bharathan NK,Dickinson AJG, Dev Biol. June 15, 2019; 450(2):1095-564X.

ANK2 functionally interacts with KCNH2 aggravating long QT syndrome in a double mutation carrier., Gessner G,Runge S,Koenen M,Heinemann SH,Koenen M,Haas J,Meder B,Thomas D,Katus HA,Schweizer PA, Biochem Biophys Res Commun. May 14, 2019; 512(4):1090-2104.

N-glycosylation-dependent regulation of hK2P17.1 currents., Wiedmann F,Schlund D,Voigt N,Ratte A,Kraft M,Katus HA,Schmidt C, Mol Biol Cell. June 1, 2019; 30(12):1939-4586.

Modeling congenital kidney diseases in Xenopus laevis., Blackburn ATM,Miller RK, Dis Model Mech. April 9, 2019; 12(4):1754-8411.

Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis., Schwenty-Lara J,Nürnberger A,Borchers A, Dev Dyn. June 1, 2019; 248(6):1058-8388.

ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer., Daulat AM,Finetti P,Revinski D,Silveira Wagner M,Camoin L,Audebert S,Birnbaum D,Kodjabachian L,Borg JP,Bertucci F, Br J Cancer. April 1, 2019; 120(9):0007-0920.

Urokinase-type plasminogen activator (uPA) is not essential for epithelial sodium channel (ENaC)-mediated sodium retention in experimental nephrotic syndrome., Bohnert BN,Daiminger S,Wörn M,Sure F,Staudner T,Ilyaskin AV,Batbouta F,Janessa A,Schneider JC,Essigke D,Kanse S,Haerteis S,Korbmacher C,Artunc F, Acta Physiol (Oxf). December 1, 2019; 227(4):1748-1716.

Visualizing flow in an intact CSF network using optical coherence tomography: implications for human congenital hydrocephalus., Date P,Ackermann P,Furey C,Fink IB,Jonas S,Khokha MK,Kahle KT,Deniz E, Sci Rep. April 17, 2019; 9(1):2045-2322.

Wolf-Hirschhorn Syndrome-Associated Genes Are Enriched in Motile Neural Crest Cells and Affect Craniofacial Development in Xenopus laevis., Mills A,Bearce E,Cella R,Kim SW,Selig M,Lee S,Lowery LA, Front Physiol. January 1, 2019; 10:1664-042X.

Aβ1-42 triggers the generation of a retrograde signaling complex from sentinel mRNAs in axons., Walker CA,Randolph LK,Matute C,Alberdi E,Baleriola J,Hengst U, EMBO Rep. July 1, 2018; 19(7):1469-3178.

DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract., Blackburn ATM,Bekheirnia N,Uma VC,Corkins ME,Xu Y,Xu Y,Rosenfeld JA,Bainbridge MN,Yang Y,Yang Y,Liu P,Madan-Khetarpal S,Delgado MR,Hudgins L,Krantz I,Rodriguez-Buritica D,Wheeler PG,Al-Gazali L,Mohamed Saeed Mohamed Al Shamsi A,Gomez-Ospina N,Chao HT,Mirzaa GM,Scheuerle AE,Kukolich MK,Scaglia F,Eng C,Willsey HR,Braun MC,Lamb DJ,Miller RK,Bekheirnia MR, Genet Med. December 1, 2019; 21(12):1530-0366.

Functional characterization of SMN evolution in mouse models of SMA., Osman EY,Bolding MR,Villalón E,Kaifer KA,Lorson ZC,Tisdale S,Hao Y,Conant GC,Pires JC,Pellizzoni L,Lorson CL, Sci Rep. July 1, 2019; 9(1):2045-2322.

Concomitant exposure to benzo[a]pyrene and triclosan at environmentally relevant concentrations induces metabolic syndrome with multigenerational consequences in Silurana (Xenopus) tropicalis., Usal M,Regnault C,Veyrenc S,Couturier K,Batandier C,Bulteau AL,Lejon D,Combourieu B,Lafond T,Raveton M,Reynaud S, Sci Total Environ. November 1, 2019; 689:1879-1026.

Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC., Argaiz ER,Chavez-Canales M,Ostrosky-Frid M,Rodríguez-Gama A,Vázquez N,Gonzalez-Rodriguez X,Garcia-Valdes J,Hadchouel J,Ellison D,Gamba G, Am J Physiol Renal Physiol. September 1, 2018; 315(3):1522-1466.

Molecular characterization of an aquaporin-2 mutation causing a severe form of nephrogenic diabetes insipidus., Saglar Ozer E,Moeller HB,Karaduman T,Fenton RA,Mergen H, Cell Mol Life Sci. March 1, 2020; 77(5):1420-9071.

The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function., Silbernagel N,Walecki M,Schäfer MK,Kessler M,Zobeiri M,Rinné S,Kiper AK,Komadowski MA,Vowinkel KS,Wemhöner K,Fortmüller L,Schewe M,Dolga AM,Scekic-Zahirovic J,Matschke LA,Culmsee C,Baukrowitz T,Monassier L,Ullrich ND,Dupuis L,Just S,Budde T,Fabritz L,Decher N, FASEB J. November 1, 2018; 32(11):1530-6860.

NA3 glycan: a potential therapy for retinal pigment epithelial deficiency., Chintalapudi SR,Wang X,Wang X,Shi Y,Shi Y,Kocak M,Palamoor M,Davis RN,Hollingsworth TJ,Jablonski MM, FEBS J. December 1, 2019; 286(24):1742-4658.

Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1., Chen M,Neul C,Schaeffeler E,Frisch F,Winter S,Schwab M,Koepsell H,Hu S,Laufer S,Baker SD,Sparreboom A,Nies AT, Clin Pharmacol Ther. January 1, 2020; 107(1):1532-6535.

Alkylglycerol monooxygenase, a heterotaxy candidate gene, regulates left-right patterning via Wnt signaling., Duncan AR,González DP,Del Viso F,Robson A,Khokha MK,Griffin JN, Dev Biol. December 1, 2019; 456(1):1095-564X.

Comparative Embryonic Spatio-Temporal Expression Profile Map of the Xenopus P2X Receptor Family., Blanchard C,Boué-Grabot E,Massé K, Front Cell Neurosci. January 1, 2019; 13:1662-5102.

Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK., Royal P,Andres-Bilbe A,Ávalos Prado P,Verkest C,Wdziekonski B,Schaub S,Baron A,Lesage F,Gasull X,Levitz J,Sandoz G, Neuron. January 16, 2019; 101(2):0896-6273.

Xenopus: Driving the Discovery of Novel Genes in Patient Disease and Their Underlying Pathological Mechanisms Relevant for Organogenesis., Hwang WY,Marquez J,Khokha MK, Front Physiol. January 1, 2019; 10:1664-042X.

De novo variants in SLC12A6 cause sporadic early-onset progressive sensorimotor neuropathy., Park J,Flores BR,Scherer K,Kuepper H,Rossi M,Rupprich K,Rautenberg M,Deininger N,Weichselbaum A,Grimm A,Sturm M,Grasshoff U,Delpire E,Haack TB, J Med Genet. April 1, 2020; 57(4):1468-6244.

Understanding cornea homeostasis and wound healing using a novel model of stem cell deficiency in Xenopus., Adil MT,Simons CM,Sonam S,Henry JJ, Exp Eye Res. October 1, 2019; 187:0014-4835.

Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis., Corkins ME,Krneta-Stankic V,Kloc M,McCrea PD,Gladden AB,Miller RK, PLoS One. January 1, 2019; 14(8):1932-6203.

Functional characterization of Kv11.1 (hERG) potassium channels split in the voltage-sensing domain., de la Peña P,Domínguez P,Barros F, Pflugers Arch. July 1, 2018; 470(7):1432-2013.

The molecular determinants of R-roscovitine block of hERG channels., Cernuda B,Fernandes CT,Allam SM,Orzillo M,Suppa G,Chia Chang Z,Athanasopoulos D,Buraei Z, PLoS One. September 3, 2019; 14(9):1932-6203.

Conservation and divergence of protein pathways in the vertebrate heart., Federspiel JD,Tandon P,Wilczewski CM,Wasson L,Herring LE,Venkatesh SS,Cristea IM,Conlon FL, PLoS Biol. September 6, 2019; 17(9):1545-7885.

Characteristics of in Vivo Model Systems for Ovarian Cancer Studies., Tudrej P,Kujawa KA,Cortez AJ,Lisowska KM, Diagnostics (Basel). September 14, 2019; 9(3):2075-4418.

ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia., Haas M,Gómez Vázquez JL,Sun DI,Tran HT,Brislinger M,Tasca A,Shomroni O,Vleminckx K,Vleminckx K,Walentek P, Cell Rep. September 24, 2019; 28(13):2211-1247.

Analyses of epithelial Na+ channel variants reveal that an extracellular β-ball domain critically regulates ENaC gating., Wang X,Chen J,Shi S,Sheng S,Kleyman TR, J Biol Chem. November 8, 2019; 294(45):1083-351X.

BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers., Kuznetsov JN,Aguero TH,Owens DA,Kurtenbach S,Field MG,Durante MA,Rodriguez DA,King ML,Harbour JW, Sci Adv. September 18, 2019; 5(9):2375-2548.

Atom-by-atom tuning of the electrostatic potassium-channel modulator dehydroabietic acid., Silverå Ejneby M,Wu X,Ottosson NE,Münger EP,Lundström I,Konradsson P,Elinder F, J Gen Physiol. May 7, 2018; 150(5):1540-7748.

Functional genomics of epilepsy-associated mutations in the GABAA receptor subunits reveal that one mutation impairs function and two are catastrophic., Absalom NL,Ahring PK,Liao VW,Balle T,Jiang T,Anderson LL,Arnold JC,McGregor IS,Bowen MT,Chebib M, J Biol Chem. April 12, 2019; 294(15):1083-351X.

Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions., Anderson LL,Absalom NL,Abelev SV,Low IK,Doohan PT,Martin LJ,Chebib M,McGregor IS,Arnold JC, Epilepsia. November 1, 2019; 60(11):1528-1167.

Quantitative Phenotyping of Xenopus Embryonic Heart Pathophysiology Using Hemoglobin Contrast Subtraction Angiography to Screen Human Cardiomyopathies., Deniz E,Jonas S,Khokha MK,Choma MA, Front Physiol. January 1, 2019; 10:1664-042X.

Volume sensing in the transient receptor potential vanilloid 4 ion channel is cell type-specific and mediated by an N-terminal volume-sensing domain., Toft-Bertelsen TL,Yarishkin O,Redmon S,Phuong TTT,Križaj D,MacAulay N, J Biol Chem. November 29, 2019; 294(48):1083-351X.

Identification of Drivers of Aneuploidy in Breast Tumors., Pfister K,Pipka JL,Chiang C,Liu Y,Clark RA,Keller R,Skoglund P,Guertin MJ,Hall IM,Stukenberg PT, Cell Rep. May 29, 2018; 23(9):2211-1247.

Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons., Cioni JM,Lin JQ,Holtermann AV,Koppers M,Jakobs MAH,Azizi A,Turner-Bridger B,Shigeoka T,Franze K,Harris WA,Holt CE, Cell. January 10, 2019; 176(1-2):1097-4172.

Homozygous Null TBX4 Mutations Lead to Posterior Amelia with Pelvic and Pulmonary Hypoplasia., Kariminejad A,Szenker-Ravi E,Lekszas C,Tajsharghi H,Moslemi AR,Naert T,Tran HT,Ahangari F,Rajaei M,Nasseri M,Haaf T,Azad A,Superti-Furga A,Maroofian R,Ghaderi-Sohi S,Najmabadi H,Abbaszadegan MR,Vleminckx K,Vleminckx K,Nikuei P,Reversade B, Am J Hum Genet. December 5, 2019; 105(6):1537-6605.

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Antiarrhythmic Properties of Ranolazine: Inhibition of Atrial Fibrillation Associated TASK-1 Potassium Channels., Ratte A,Wiedmann F,Kraft M,Katus HA,Schmidt C, Front Pharmacol. July 3, 2019; 10:1663-9812.

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The FOXJ1 target Cfap206 is required for sperm motility, mucociliary clearance of the airways and brain development., Beckers A,Adis C,Schuster-Gossler K,Tveriakhina L,Ott T,Fuhl F,Hegermann J,Boldt K,Serth K,Rachev E,Alten L,Kremmer E,Ueffing M,Blum M,Gossler A, Development. June 15, 2020; 147(21):1477-9129.

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The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology., Barnum CE,Al Saai S,Patel SD,Cheng C,Anand D,Xu X,Dash S,Siddam AD,Glazewski L,Paglione E,Polson SW,Chuma S,Mason RW,Wei S,Batish M,Fowler VM,Lachke SA, Hum Mol Genet. July 29, 2020; 29(12):1460-2083.

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KCNC1-related disorders: new de novo variants expand the phenotypic spectrum., Park J,Koko M,Hedrich UBS,Hermann A,Cremer K,Haberlandt E,Grimmel M,Alhaddad B,Beck-Woedl S,Harrer M,Karall D,Kingelhoefer L,Tzschach A,Matthies LC,Strom TM,Ringelstein EB,Sturm M,Engels H,Wolff M,Lerche H,Haack TB, Ann Clin Transl Neurol. July 1, 2019; 6(7):2328-9503.

Identification of Transient Receptor Potential Channel 4-Associated Protein as a Novel Candidate Gene Causing Congenital Primary Hypothyroidism., Choukair D,Eberle B,Vick P,Hermanns P,Weiss B,Paramasivam N,Schlesner M,Lornsen K,Roeth R,Klutmann C,Kreis J,Hoffmann GF,Pohlenz J,Rappold GA,Bettendorf M, Horm Res Paediatr. January 1, 2020; 93(1):1663-2826.

Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors., Prevost MS,Bouchenaki H,Barilone N,Gielen M,Corringer PJ, Cell Mol Life Sci. February 1, 2021; 78(3):1420-9071.

Association of A Novel Splice Site Mutation in P/Q-Type Calcium Channels with Childhood Epilepsy and Late-Onset Slowly Progressive Non-Episodic Cerebellar Ataxia., Stendel C,D'Adamo MC,Wiessner M,Dusl M,Cenciarini M,Belia S,Nematian-Ardestani E,Bauer P,Senderek J,Klopstock T,Pessia M, Int J Mol Sci. May 27, 2020; 21(11):1422-0067.

The neurodevelopmental disorder risk gene DYRK1A is required for ciliogenesis and control of brain size in Xenopus embryos., Willsey HR,Xu Y,Xu Y,Everitt A,Dea J,Exner CRT,Willsey AJ,State MW,Harland RM, Development. June 22, 2020; 147(21):1477-9129.

Andersen-Tawil Syndrome Is Associated With Impaired PIP2 Regulation of the Potassium Channel Kir2.1., Handklo-Jamal R,Meisel E,Yakubovich D,Vysochek L,Beinart R,Glikson M,McMullen JR,Dascal N,Nof E,Oz S, Front Pharmacol. April 7, 2020; 11:1663-9812.

pH dependence of the Slc4a11-mediated H+ conductance is influenced by intracellular lysine residues and modified by disease-linked mutations., Quade BN,Marshall A,Parker MD, Am J Physiol Cell Physiol. August 1, 2020; 319(2):1522-1563.

POPDC2 a novel susceptibility gene for conduction disorders., Rinné S,Ortiz-Bonnin B,Stallmeyer B,Kiper AK,Fortmüller L,Schindler RFR,Herbort-Brand U,Kabir NS,Dittmann S,Friedrich C,Zumhagen S,Gualandi F,Selvatici R,Rapezzi C,Arbustini E,Ferlini A,Fabritz L,Schulze-Bahr E,Brand T,Decher N, J Mol Cell Cardiol. August 1, 2020; 145:1095-8584.

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Molecular Regulation of α3β4 Nicotinic Acetylcholine Receptors by Lupeol in Cardiovascular System., Eom S,Kim C,Yeom HD,Lee J,Lee J,Lee S,Baek YB,Na J,Park SI,Kim GY,Lee CM,Lee CM,Lee CM,Lee JH,Lee JH, Int J Mol Sci. June 18, 2020; 21(12):1422-0067.

Contribution of Monocarboxylate Transporter 6 to the Pharmacokinetics and Pharmacodynamics of Bumetanide in Mice., Jones RS,Ruszaj D,Parker MD,Morris ME, Drug Metab Dispos. September 1, 2020; 48(9):1521-009X.

DLG5 variants are associated with multiple congenital anomalies including ciliopathy phenotypes., Marquez J,Mann N,Arana K,Deniz E,Ji W,Konstantino M,Mis EK,Deshpande C,Jeffries L,McGlynn J,Hugo H,Widmeier E,Konrad M,Tasic V,Morotti R,Baptista J,Ellard S,Lakhani SA,Hildebrandt F,Khokha MK, J Med Genet. July 1, 2021; 58(7):1468-6244.

Mambalgin-2 Induces Cell Cycle Arrest and Apoptosis in Glioma Cells via Interaction with ASIC1a., Bychkov M,Shulepko M,Osmakov D,Andreev Y,Sudarikova A,Vasileva V,Pavlyukov MS,Latyshev YA,Potapov AA,Kirpichnikov M,Shenkarev ZO,Lyukmanova E, Cancers (Basel). July 8, 2020; 12(7):2072-6694.

A novel homozygous mutation (p.N958K) of SLC12A3 in Gitelman syndrome is associated with endoplasmic reticulum stress., Tang W,Huang X,Liu Y,Lv Q,Li T,Song Y,Zhang X,Chen X,Shi Y,Shi Y, J Endocrinol Invest. March 1, 2021; 44(3):0391-4097.

Electrophysiological effects of non-vitamin K antagonist oral anticoagulants on atrial repolarizing potassium channels., Wiedmann F,Schlund D,Kraft M,Nietfeld J,Katus HA,Schmidt C,Thomas D, Europace. September 1, 2020; 22(9):1532-2092.

Interplay of TRIM2 E3 Ubiquitin Ligase and ALIX/ESCRT Complex: Control of Developmental Plasticity During Early Neurogenesis., Lokapally A,Neuhaus H,Herfurth J,Hollemann T, Cells. July 20, 2020; 9(7):2073-4409.

Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site., Smith SJ,Towers N,Demetriou K,Mohun TJ, PLoS One. July 29, 2020; 15(7):1932-6203.

Rare heterozygous GDF6 variants in patients with renal anomalies., Martens H,Hennies I,Getwan M,Christians A,Weiss AC,Brand F,Gjerstad AC,Christians A,Gucev Z,Geffers R,Seeman T,Kispert A,Tasic V,Bjerre A,Lienkamp SS,Haffner D,Weber RG, Eur J Hum Genet. December 1, 2020; 28(12):1476-5438.

Grp94 Regulates the Recruitment of Aneural AChR Clusters for the Assembly of Postsynaptic Specializations by Modulating ADF/Cofilin Activity and Turnover., Chan ZC,Deng L,Lee CW,Lee CW,Lee CW, eNeuro. September 8, 2020; 7(5):2373-2822.

In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders., Grupe M,Bentzen BH,Benned-Jensen T,Nielsen V,Frederiksen K,Jensen HS,Jacobsen AM,Skibsbye L,Sams AG,Grunnet M,Rottländer M,Bastlund JF, Eur J Pharmacol. November 15, 2020; 887:1879-0712.

Sprouty2 regulates positioning of retinal progenitors through suppressing the Ras/Raf/MAPK pathway., Sun J,Yoon J,Lee M,Hwang YS,Daar IO, Sci Rep. August 13, 2020; 10(1):2045-2322.

Uncoupling sodium channel dimers restores the phenotype of a pain-linked Nav 1.7 channel mutation., Rühlmann AH,Körner J,Hausmann R,Bebrivenski N,Neuhof C,Detro-Dassen S,Hautvast P,Benasolo CA,Meents J,Machtens JP,Schmalzing G,Lampert A, Br J Pharmacol. October 1, 2020; 177(19):1476-5381.

Characterization of AN317, a novel selective agonist of α6β2-containing nicotinic acetylcholine receptors., Sandager-Nielsen K,Ahring PK,Klein J,van Hout M,Thaneshwaran S,Dos Santos AB,Jacobsen TA,Amrutkar DV,Peters D,Jensen AA,Kohlmeier KA,Christophersen P,Dyhring T, Biochem Pharmacol. April 1, 2020; 174:1873-2968.

Tetrapeptide Ac-HAEE-NH2 Protects α4β2 nAChR from Inhibition by Aβ., Barykin EP,Garifulina AI,Tolstova AP,Anashkina AA,Adzhubei AA,Mezentsev YV,Shelukhina IV,Kozin SA,Tsetlin VI,Makarov AA, Int J Mol Sci. August 29, 2020; 21(17):1422-0067.

Acute consequences of a unilateral VIIIth nerve transection on vestibulo-ocular and optokinetic reflexes in Xenopus laevis tadpoles., Soupiadou P,Gordy C,Forsthofer M,Sanchez-Gonzalez R,Straka H, J Neurol. December 1, 2020; 267(Suppl 1):1432-1459.

Establishing embryonic territories in the context of Wnt signaling., Velloso I,Maia LA,Amado NG,Reis AH,He X,Abreu JG, Int J Dev Biol. January 1, 2021; 65(4-5-6):1696-3547.

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M,Amado N,Tan J,Reis A,Ge M,Abreu JG,He X, Elife. September 14, 2020; 9:2050-084X.

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Amiodarone bioconcentration and suppression of metamorphosis in Xenopus., Sanoh S,Hanada H,Kashiwagi K,Mori T,Goto-Inoue N,Suzuki KT,Mori J,Nakamura N,Yamamoto T,Kitamura S,Kotake Y,Sugihara K,Ohta S,Kashiwagi A, Aquat Toxicol. November 1, 2020; 228:1879-1514.

A nonsense variant in Rap Guanine Nucleotide Exchange Factor 5 (RAPGEF5) is associated with equine familial isolated hypoparathyroidism in Thoroughbred foals., Rivas VN,Magdesian KG,Fagan S,Slovis NM,Luethy D,Javsicas LH,Caserto BG,Miller AD,Dahlgren AR,Peterson J,Hales EN,Peng S,Watson KD,Khokha MK,Finno CJ, PLoS Genet. September 28, 2020; 16(9):1553-7404.

Alignment of Alzheimer's disease amyloid β-peptide and klotho., Lehrer S,Rheinstein PH, World Acad Sci J. January 1, 2020; 2(6):2632-2919.

The Stemness Gene Mex3A Is a Key Regulator of Neuroblast Proliferation During Neurogenesis., Naef V,De Sarlo M,Testa G,Corsinovi D,Azzarelli R,Borello U,Ori M, Front Cell Dev Biol. January 1, 2020; 8:2296-634X.

A Common Kinetic Property of Mutations Linked to Episodic Ataxia Type 1 Studied in the Shaker Kv Channel., Zhao J,Petitjean D,Haddad GA,Batulan Z,Blunck R, Int J Mol Sci. October 14, 2020; 21(20):1422-0067.

Nucleoporin NUP205 plays a critical role in cilia and congenital disease., Marquez J,Bhattacharya D,Lusk CP,Khokha MK, Dev Biol. January 1, 2021; 469:1095-564X.

S-nitrosylation of connexin43 hemichannels elicits cardiac stress-induced arrhythmias in Duchenne muscular dystrophy mice., Lillo MA,Himelman E,Shirokova N,Xie LH,Fraidenraich D,Contreras JE, JCI Insight. December 19, 2019; 4(24):2379-3708.

Dual Screen for Efficacy and Toxicity Identifies HDAC Inhibitor with Distinctive Activity Spectrum for BAP1-Mutant Uveal Melanoma., Kuznetsoff JN,Owens DA,Lopez A,Rodriguez DA,Chee NT,Kurtenbach S,Bilbao D,Roberts ER,Volmar CH,Wahlestedt C,Brothers SP,Harbour JW, Mol Cancer Res. February 1, 2021; 19(2):1557-3125.

Disease-associated HCN4 V759I variant is not sufficient to impair cardiac pacemaking., Erlenhardt N,Kletke O,Wohlfarth F,Komadowski MA,Clasen L,Makimoto H,Rinné S,Kelm M,Jungen C,Decher N,Meyer C,Klöcker N, Pflugers Arch. December 1, 2020; 472(12):1432-2013.

Structural bioinformatics predicts that the Retinitis Pigmentosa-28 protein of unknown function FAM161A is a homologue of the microtubule nucleation factor Tpx2., Levine TP, F1000Res. January 1, 2020; 9:2046-1402.

Potential reproductive toxicity of multi-walled carbon nanotubes and their chronic exposure effects on the growth and development of Xenopus tropicalis., Zhao J,Luo W,Xu Y,Xu Y,Ling J,Deng L, Sci Total Environ. April 20, 2021; 766:1879-1026.

The anticonvulsant zonisamide positively modulates recombinant and native glycine receptors at clinically relevant concentrations., Devenish SO,Winters BL,Anderson LL,Arnold JC,McGregor IS,Vaughan CW,Chebib M,Absalom NL, Neuropharmacology. January 1, 2021; 182:1873-7064.

Voltage-Dependent Dopamine Potency at D1-Like Dopamine Receptors., Ågren R,Sahlholm K, Front Pharmacol. April 7, 2020; 11:1663-9812.

Allosteric regulation of mammalian Na+/I- symporter activity by perchlorate., Llorente-Esteban A,Manville RW,Reyna-Neyra A,Abbott GW,Amzel LM,Carrasco N, Nat Struct Mol Biol. June 1, 2020; 27(6):1545-9985.

Increased Dissociation of Adamantanamines in Influenza A M2 S31N with Partial Block by Rimantadine., McGuire KL,Hill JT,Busath DD, Biophys J. November 3, 2020; 119(9):1542-0086.

Functional Integrity of Synapses in the Central Nervous System of Cognitively Intact Individuals with High Alzheimer's Disease Neuropathology Is Associated with Absence of Synaptic Tau Oligomers., Singh A,Allen D,Fracassi A,Tumurbaatar B,Natarajan C,Scaduto P,Woltjer R,Kayed R,Limon A,Krishnan B,Taglialatela G, J Alzheimers Dis. January 1, 2020; 78(4):1875-8908.

Building neuromuscular junctions in vitro., Barbeau S,Tahraoui-Bories J,Legay C,Martinat C, Development. November 16, 2020; 147(22):1477-9129.

DAAM2 Variants Cause Nephrotic Syndrome via Actin Dysregulation., Schneider R,Deutsch K,Hoeprich GJ,Marquez J,Hermle T,Braun DA,Seltzsam S,Kitzler TM,Mao Y,Buerger F,Majmundar AJ,Onuchic-Whitford AC,Kolvenbach CM,Schierbaum L,Schneider S,Halawi AA,Nakayama M,Mann N,Connaughton DM,Klämbt V,Wagner M,Riedhammer KM,Renders L,Katsura Y,Thumkeo D,Soliman NA,Mane S,Lifton RP,Shril S,Khokha MK,Hoefele J,Goode BL,Hildebrandt F, Am J Hum Genet. December 3, 2020; 107(6):1537-6605.

A System for Assessing Dual Action Modulators of Glycine Transporters and Glycine Receptors., Sheipouri D,Gallagher CI,Shimmon S,Rawling T,Vandenberg RJ, Biomolecules. November 30, 2020; 10(12):2218-273X.

Characterization of the GABRB2-Associated Neurodevelopmental Disorders., El Achkar CM,Harrer M,Smith L,Kelly M,Iqbal S,Maljevic S,Niturad CE,Vissers LELM,Poduri A,Yang E,Lal D,Lerche H,Møller RS,Olson HE, Ann Neurol. March 1, 2021; 89(3):1531-8249.

Familial neonatal seizures caused by the Kv7.3 selectivity filter mutation T313I., Maghera J,Li J,Lamothe SM,Braun M,Appendino JP,Au PYB,Kurata HT, Epilepsia Open. December 1, 2020; 5(4):2470-9239.

Differential Coassembly of α1-GABAARs Associated with Epileptic Encephalopathy., Hannan S,Affandi AHB,Minere M,Jones C,Goh P,Warnes G,Popp B,Trollmann R,Nizetic D,Smart TG, J Neurosci. July 15, 2020; 40(29):1529-2401.

Xenopus leads the way: Frogs as a pioneering model to understand the human brain., Exner CRT,Willsey HR, Genesis. February 1, 2021; 59(1-2):1526-968X.

Editorial: Xenopus Models of Organogenesis and Disease., Griffin JN,Liu KJ,Liu KJ,Sempou E, Front Physiol. January 1, 2020; 11:1664-042X.

Phosphorylation of a chronic pain mutation in the voltage-gated sodium channel Nav1.7 increases voltage sensitivity., Kerth CM,Hautvast P,Körner J,Lampert A,Meents JE, J Biol Chem. January 1, 2021; 296:1083-351X.

Xenopus epidermal and endodermal epithelia as models for mucociliary epithelial evolution, disease, and metaplasia., Walentek P, Genesis. February 1, 2021; 59(1-2):1526-968X.

Distinct roles for prominin-1 and photoreceptor cadherin in outer segment disc morphogenesis in CRISPR-altered X. laevis., Carr BJ,Stanar P,Moritz OL, J Cell Sci. January 11, 2021; 134(1):1477-9137.

Developing Tadpole Xenopus laevis as a Comparative Animal Model to Study Mycobacterium abscessus Pathogenicity., Lopez A,Shoen C,Cynamon M,Dimitrakopoulou D,Paiola M,Pavelka MS,Robert J, Int J Mol Sci. January 15, 2021; 22(2):1422-0067.

TRESK and TREK-2 two-pore-domain potassium channel subunits form functional heterodimers in primary somatosensory neurons., Lengyel M,Czirják G,Jacobson DA,Enyedi P, J Biol Chem. August 28, 2020; 295(35):1083-351X.

Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds., Kowalczyk I,Lee C,Lee C,Lee C,Schuster E,Hoeren J,Trivigno V,Riedel L,Görne J,Wallingford JB,Hammes A,Feistel K, Development. January 26, 2021; 148(2):1477-9129.

Molecular Mechanism of Autosomal Recessive Long QT-Syndrome 1 without Deafness., Oertli A,Rinné S,Moss R,Kääb S,Seemann G,Beckmann BM,Decher N, Int J Mol Sci. January 23, 2021; 22(3):1422-0067.

Aquatic models of human ciliary diseases., Corkins ME,Krneta-Stankic V,Kloc M,Miller RK, Genesis. February 1, 2021; 59(1-2):1526-968X.

Quantifying the dose-dependent impact of intracellular amyloid beta in a mathematical model of calcium regulation in xenopus oocyte., Minicucci J,Alfond M,Demuro A,Gerberry D,Latulippe J, PLoS One. January 28, 2021; 16(1):1932-6203.

Use of Xenopus laevis cell-free extracts to study BRCA2 role in chromosome alignment., El Dika M, DNA Repair (Amst). April 1, 2021; 100:1568-7856.

Xenopus to the rescue: A model to validate and characterize candidate ciliopathy genes., Rao VG,Kulkarni SS, Genesis. February 1, 2021; 59(1-2):1526-968X.

Retinol binding protein 1 affects Xenopus anterior neural development via all-trans retinoic acid signaling., Flach H,Basten T,Schreiner C,Dietmann P,Greco S,Nies L,Roßmanith N,Walter S,Kühl M,Kühl SJ, Dev Dyn. August 1, 2021; 250(8):1058-8388.

Mutations in PRDM15 Are a Novel Cause of Galloway-Mowat Syndrome., Mann N,Mzoughi S,Schneider R,Kühl SJ,Schanze D,Klämbt V,Lovric S,Mao Y,Shi S,Tan W,Kühl M,Onuchic-Whitford AC,Treimer E,Kitzler TM,Kause F,Schumann S,Nakayama M,Buerger F,Shril S,van der Ven AT,Majmundar AJ,Holton KM,Kolb A,Braun DA,Rao J,Jobst-Schwan T,Mildenberger E,Lennert T,Kuechler A,Wieczorek D,Gross O,Ermisch-Omran B,Werberger A,Skalej M,Janecke AR,Soliman NA,Mane SM,Lifton RP,Kadlec J,Guccione E,Schmeisser MJ,Zenker M,Hildebrandt F, J Am Soc Nephrol. March 1, 2021; 32(3):1533-3450.

Biallelic variants in COPB1 cause a novel, severe intellectual disability syndrome with cataracts and variable microcephaly., Macken WL,Godwin A,Wheway G,Stals K,Nazlamova L,Ellard S,Alfares A,Aloraini T,AlSubaie L,Alfadhel M,Alajaji S,Wai HA,Self J,Douglas AGL,Kao AP,Guille M,Baralle D, Genome Med. February 25, 2021; 13(1):1756-994X.

Sleep-related hypermotor epilepsy associated mutations uncover important kinetic roles of α4β2- nicotinic acetylcholine receptor intracellular structures., Weltzin MM,George AA,Lukas RJ,Whiteaker P, PLoS One. March 3, 2021; 16(3):1932-6203.

Functional and Structural Characterization of ClC-1 and Nav1.4 Channels Resulting from CLCN1 and SCN4A Mutations Identified Alone and Coexisting in Myotonic Patients., Brenes O,Barbieri R,Vásquez M,Vindas-Smith R,Roig J,Romero A,Valle GD,Bermúdez-Guzmán L,Bertelli S,Pusch M,Morales F, Cells. February 11, 2021; 10(2):2073-4409.

Differential Regulation of Human Serotonin Receptor Type 3A by Chanoclavine and Ergonovine., Eom S,Jung W,Lee J,Lee J,Yeom HD,Lee S,Kim C,Park HD,Lee JH,Lee JH, Molecules. February 24, 2021; 26(5):1420-3049.

BRCA1-BARD1 regulates transcription through BRD4 in Xenopus nucleoplasmic extract., Barrows JK,Fullbright G,Long DT, Nucleic Acids Res. April 6, 2021; 49(6):1362-4962.

High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability., Matson DR,Denu RA,Zasadil LM,Burkard ME,Weaver BA,Flynn C,Stukenberg PT, BMC Cancer. February 23, 2021; 21(1):1471-2407.

Thyroid Disrupting Chemicals in Mixture Perturb Thymocyte Differentiation in Xenopus laevis Tadpoles., McGuire CC,Lawrence BP,Robert J, Toxicol Sci. May 27, 2021; 181(2):1096-0929.

Compound Heterozygous KCNQ1 Mutations Causing Recessive Romano-Ward Syndrome: Functional Characterization by Mutant Co-expression., González-Garrido A,Domínguez-Pérez M,Jacobo-Albavera L,López-Ramírez O,Guevara-Chávez JG,Zepeda-García O,Iturralde P,Carnevale A,Villarreal-Molina T, Front Cardiovasc Med. February 22, 2021; 8:2297-055X.

Cation leak underlies neuronal excitability in an HCN1 developmental and epileptic encephalopathy., Bleakley LE,McKenzie CE,Soh MS,Forster IC,Pinares-Garcia P,Sedo A,Kathirvel A,Churilov L,Jancovski N,Maljevic S,Berkovic SF,Scheffer IE,Petrou S,Santoro B,Reid CA, Brain. August 17, 2021; 144(7):1460-2156.

Dissecting the Molecular Determinants of GABAA Receptors Current Rundown, a Hallmark of Refractory Human Epilepsy., Cifelli P,Di Angelantonio S,Alfano V,Morano A,De Felice E,Aronica E,Ruffolo G,Palma E, Brain Sci. March 30, 2021; 11(4):2076-3425.

Bioelectric signaling: Reprogrammable circuits underlying embryogenesis, regeneration, and cancer., Levin M, Cell. April 15, 2021; :1097-4172.

N-terminal region of RecQ4 inhibits non-homologous end joining and chromatin association of the Ku heterodimer in Xenopus egg extracts., Tsuyama T,Fujita K,Sasaki R,Hamanaka S,Sotoyama Y,Ogawa A,Kusuzaki K,Azuma Y,Tada S, Gene. June 30, 2021; 787:1879-0038.

Structure Basis for Shaping the Nse4 Protein by the Nse1 and Nse3 Dimer within the Smc5/6 Complex., Jo A,Li S,Shin JW,Zhao X,Cho Y, J Mol Biol. April 30, 2021; 433(9):1089-8638.

Molecular mechanisms of hearing loss in Nager syndrome., Maharana SK,Saint-Jeannet JP, Dev Biol. August 1, 2021; 476:1095-564X.

Functional rice with tandemly repeated Cbl-b ubiquitin ligase inhibitory pentapeptide prevents denervation-induced muscle atrophy in vivo., Akama K,Shimajiri Y,Kainou K,Iwasaki R,Nakao R,Nikawa T,Nishikawa A, Biosci Biotechnol Biochem. May 25, 2021; 85(6):1347-6947.

Chronic Exposure to Two Gestagens Differentially Alters Morphology and Gene Expression in Silurana tropicalis., Thomson P,Pineda M,Yargeau V,Langlois VS, Arch Environ Contam Toxicol. May 1, 2021; 80(4):0090-4341.

Signaling Control of Mucociliary Epithelia: Stem Cells, Cell Fates, and the Plasticity of Cell Identity in Development and Disease., Walentek P, Cells Tissues Organs. January 1, 2022; 211(6):1422-6405.

WIN55,212-2, a Dual Modulator of Cannabinoid Receptors and G Protein-Coupled Inward Rectifier Potassium Channels., An D,Peigneur S,Tytgat J, Biomedicines. April 28, 2021; 9(5):2227-9059.

Loss-of-function variants in Kv 11.1 cardiac channels as a biomarker for SUDEP., Soh MS,Bagnall RD,Bennett MF,Bleakley LE,Mohamed Syazwan ES,Phillips AM,Chiam MDF,McKenzie CE,Hildebrand M,Crompton D,Bahlo M,Semsarian C,Scheffer IE,Berkovic SF,Reid CA, Ann Clin Transl Neurol. July 1, 2021; 8(7):2328-9503.

Reconstitution of β-adrenergic regulation of CaV1.2: Rad-dependent and Rad-independent protein kinase A mechanisms., Katz M,Subramaniam S,Chomsky-Hecht O,Tsemakhovich V,Flockerzi V,Klussmann E,Hirsch JA,Weiss S,Dascal N, Proc Natl Acad Sci U S A. May 25, 2021; 118(21):1091-6490.

Anaplastic lymphoma kinase (alk), a neuroblastoma associated gene, is expressed in neural crest domains during embryonic development of Xenopus., Moreno MM,Barrell WB,Godwin A,Guille M,Liu KJ,Liu KJ, Gene Expr Patterns. June 1, 2021; 40:1567-133X.

Modeling endoderm development and disease in Xenopus., Edwards NA,Zorn AM, Curr Top Dev Biol. January 1, 2021; 145:1557-8933.

Protein phosphatase 2A holoenzymes regulate leucine-rich repeat kinase 2 phosphorylation and accumulation., Drouyer M,Bolliger MF,Lobbestael E,Van den Haute C,Emanuele M,Lefebvre R,Sibran W,De Wit T,Leghay C,Mutez E,Dzamko N,Halliday GM,Murayama S,Martoriati A,Cailliau K,Bodart JF,Chartier-Harlin MC,Baekelandt V,Nichols RJ,Taymans JM, Neurobiol Dis. September 1, 2021; 157:1095-953X.

Fosl1 is vital to heart regeneration upon apex resection in adult Xenopus tropicalis., Wu HY,Zhou YM,Liao ZQ,Zhong JW,Liu YB,Zhao H,Liang CQ,Huang RJ,Park KS,Feng SS,Zheng L,Cai DQ,Qi XF, NPJ Regen Med. June 29, 2021; 6(1):2057-3995.

Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons., Hahn I,Voelzmann A,Parkin J,Fülle JB,Slater PG,Lowery LA,Sanchez-Soriano N,Prokop A, PLoS Genet. July 1, 2021; 17(7):1553-7404.

Recurrent seizure-related GRIN1 variant: Molecular mechanism and targeted therapy., Xu Y,Xu Y,Song R,Chen W,Strong K,Shrey D,Gedela S,Traynelis SF,Zhang G,Yuan H, Ann Clin Transl Neurol. July 1, 2021; 8(7):2328-9503.

A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts., Grosch M,Brunner K,Ilyaskin AV,Schober M,Staudner T,Schmied D,Stumpp T,Schmidt KN,Madej MG,Pessoa TD,Othmen H,Kubitza M,Osten L,de Vries U,Mair MM,Somlo S,Moser M,Kunzelmann K,Ziegler C,Haerteis S,Korbmacher C,Witzgall R, J Cell Sci. August 15, 2021; 134(16):1477-9137.

A convergent molecular network underlying autism and congenital heart disease., Rosenthal SB,Willsey HR,Xu Y,Xu Y,Mei Y,Dea J,Wang S,Curtis C,Sempou E,Khokha MK,Chi NC,Willsey AJ,Fisch KM,Ideker T, Cell Syst. November 17, 2021; 12(11):2405-4720.

Genetic and Physiological Effects of Insulin on Human Urate Homeostasis., Mandal AK,Leask MP,Estiverne C,Choi HK,Merriman TR,Mount DB, Front Physiol. January 1, 2021; 12:1664-042X.

Influence of Sox protein SUMOylation on neural development and regeneration., Chang KC, Neural Regen Res. March 1, 2022; 17(3):1673-5374.

Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod., Alejevski F,Leemans M,Gaillard AL,Leistenschneider D,de Flori C,Bougerol M,Le Mével S,Herrel A,Fini JB,Pézeron G,Tostivint H, Open Biol. August 1, 2021; 11(8):2046-2441.

A role for zinc transporter gene SLC39A12 in the nervous system and beyond., Davis DN,Strong MD,Chambers E,Hart MD,Bettaieb A,Clarke SL,Smith BJ,Stoecker BJ,Lucas EA,Lin D,Chowanadisai W, Gene. October 5, 2021; 799:1879-0038.

Crosstalk between repair pathways elicits double-strand breaks in alkylated DNA and implications for the action of temozolomide., Fuchs RP,Isogawa A,Paulo JA,Onizuka K,Takahashi T,Amunugama R,Duxin JP,Fujii S, Elife. July 8, 2021; 10:2050-084X.

KCNK18 Biallelic Variants Associated with Intellectual Disability and Neurodevelopmental Disorders Alter TRESK Channel Activity., Pavinato L,Nematian-Ardestani E,Zonta A,De Rubeis S,Buxbaum J,Mancini C,Bruselles A,Tartaglia M,Pessia M,Tucker SJ,D'Adamo MC,Brusco A, Int J Mol Sci. June 4, 2021; 22(11):1422-0067.

Weight of Evidence and Human Relevance Evaluation of the Benfluralin Mode of Action in Rats (Part II): Thyroid carcinogenesis., Strupp C,Quesnot N,Weber-Parmentier C,Richert L,Bomann WH,Singh P, Regul Toxicol Pharmacol. November 1, 2020; 117:1096-0295.

GlyT1 encephalopathy: Characterization of presumably disease causing GlyT1 mutations., Hauf K,Barsch L,Bauer D,Buchert R,Armbruster A,Frauenfeld L,Grasshoff U,Eulenburg V, Neurochem Int. October 1, 2020; 139:1872-9754.

Comparative analysis of alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism ATP1A3 mutations reveals functional deficits, which do not correlate with disease severity., Lazarov E,Hillebrand M,Schröder S,Ternka K,Hofhuis J,Ohlenbusch A,Barrantes-Freer A,Pardo LA,Fruergaard MU,Nissen P,Brockmann K,Gärtner J,Rosewich H, Neurobiol Dis. September 1, 2020; 143:1095-953X.

Mechanosensitive TREK-1 two-pore-domain potassium (K2P) channels in the cardiovascular system., Wiedmann F,Rinné S,Donner B,Decher N,Katus HA,Schmidt C, Prog Biophys Mol Biol. January 1, 2021; 159:1873-1732.

Discovery of Dihydropyrrolo[1,2-a]pyrazin-3(4H)-one-Based Second-Generation GluN2C- and GluN2D-Selective Positive Allosteric Modulators (PAMs) of the N-Methyl-d-Aspartate (NMDA) Receptor., Epplin MP,Mohan A,Harris LD,Zhu Z,Strong KL,Bacsa J,Le P,Menaldino DS,Traynelis SF,Liotta DC, J Med Chem. July 23, 2020; 63(14):1520-4804.

Function of chromatin modifier Hmgn1 during neural crest and craniofacial development., Ihewulezi C,Saint-Jeannet JP, Genesis. October 1, 2021; 59(10):1526-968X.

Biochemical and developmental effects of thyroid and anti-thyroid drugs on different early life stages of Xenopus laevis., Boran F,Güngördü A, Environ Toxicol Pharmacol. October 1, 2021; 87:1872-7077.

Modeling human congenital disorders with neural crest developmental defects using patient-derived induced pluripotent stem cells., Okuno H,Okano H, Regen Ther. August 24, 2021; 18:2352-3204.

Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease., Getwan M,Hoppmann A,Schlosser P,Grand K,Song W,Diehl R,Schroda S,Heeg F,Deutsch K,Hildebrandt F,Lausch E,Köttgen A,Lienkamp SS, Proc Natl Acad Sci U S A. September 28, 2021; 118(39):1091-6490.

Characterization of a Compound Heterozygous SLC2A9 Mutation That Causes Hypouricemia., Yoon J,Cachau R,David VA,Thompson M,Jung W,Jee SH,Daar IO,Winkler CA,Cho SK, Biomedicines. September 6, 2021; 9(9):2227-9059.

The Role of RNA-Binding Proteins in Vertebrate Neural Crest and Craniofacial Development., Forman TE,Dennison BJC,Fantauzzo KA, J Dev Biol. August 27, 2021; 9(3):2221-3759.

Physical basis for distinct basal and mechanically gated activity of the human K+ channel TRAAK., Rietmeijer RA,Sorum B,Li B,Brohawn SG, Neuron. September 15, 2021; 109(18):0896-6273.

Structural comparison of GLUT1 to GLUT3 reveal transport regulation mechanism in sugar porter family., Custódio TF,Paulsen PA,Frain KM,Pedersen BP, Life Sci Alliance. February 3, 2021; 4(4):2575-1077.

Teriflunomide Promotes Oligodendroglial 8,9-Unsaturated Sterol Accumulation and CNS Remyelination., Martin E,Aigrot MS,Lamari F,Bachelin C,Lubetzki C,Nait Oumesmar B,Zalc B,Stankoff B, Neurol Neuroimmunol Neuroinflamm. November 1, 2021; 8(6):2332-7812.

Translocation of TMEM175 Lysosomal Potassium Channel to the Plasma Membrane by Dynasore Compounds., Pergel E,Veres I,Csigi GI,Czirják G, Int J Mol Sci. September 29, 2021; 22(19):1422-0067.

Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects., Galgoczi S,Ruzo A,Markopoulos C,Yoney A,Phan-Everson T,Li S,Haremaki T,Metzger JJ,Etoc F,Brivanlou AH, Development. October 1, 2021; 148(19):1477-9129.

Generation of a new six1-null line in Xenopus tropicalis for study of development and congenital disease., Coppenrath K,Tavares ALP,Shaidani NI,Wlizla M,Moody SA,Horb M, Genesis. December 1, 2021; 59(12):1526-968X.

A novel I551F variant of the Na+/HCO3- cotransporter NBCe1-A shows reduced cell surface expression, resulting in diminished transport activity., Yamazaki O,Yamashita M,Li J,Ochiai-Homma F,Yoshida T,Hirahashi J,Furukawa T,Kozuma K,Fujigaki Y,Seki G,Hayashi M,Shibata S, Am J Physiol Renal Physiol. December 1, 2021; 321(6):1522-1466.

Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension., Lakk M,Hoffmann GF,Gorusupudi A,Enyong E,Lin A,Bernstein PS,Toft-Bertelsen T,MacAulay N,Elliott MH,Križaj D, J Lipid Res. January 1, 2021; 62:0022-2275.

Deep learning is widely applicable to phenotyping embryonic development and disease., Naert T,Çiçek Ö,Ogar P,Bürgi M,Shaidani NI,Kaminski MM,Xu Y,Xu Y,Grand K,Vujanovic M,Prata D,Hildebrandt F,Brox T,Ronneberger O,Voigt FF,Helmchen F,Loffing J,Horb ME,Willsey HR,Lienkamp SS, Development. November 1, 2021; 148(21):1477-9129.

Kv3.1 channelopathy: a novel loss-of-function variant and the mechanistic basis of its clinical phenotypes., Li X,Zheng Y,Li S,Nair U,Sun C,Zhao C,Lu J,Zhang VW,Maljevic S,Petrou S,Lin J, Ann Transl Med. September 1, 2021; 9(18):2305-5839.

Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutant., Tong JJ,Khan U,Haddad BG,Minogue PJ,Beyer EC,Berthoud VM,Reichow SL,Ebihara L, Biophys J. December 21, 2021; 120(24):1542-0086.

Virus-Host Interactions of Enteroviruses and Parvovirus B19 in Myocarditis., Ho HT,Peischard S,Strutz-Seebohm N,Seebohm G, Cell Physiol Biochem. November 18, 2021; 55(6):1421-9778.

Ion permeation controlled by hydrophobic residues and proton binding in the proton-activated chloride channel., Cai R,Tang J,Chen XZ, iScience. November 1, 2021; 24(12):2589-0042.

Frequent SLC12A3 mutations in Chinese Gitelman syndrome patients: structure and function disorder., Jiang L,Peng X,Zhao B,Zhang L,Xu L,Li X,Nie M,Chen L, Endocr Connect. January 27, 2022; 11(1):2049-3614.

Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice., Artunc F,Bohnert BN,Schneider JC,Staudner T,Sure F,Ilyaskin AV,Wörn M,Essigke D,Janessa A,Nielsen NV,Birkenfeld AL,Etscheid M,Haerteis S,Korbmacher C,Kanse SM, Pflugers Arch. February 1, 2022; 474(2):1432-2013.

Identification of SCN5a p.C335R Variant in a Large Family with Dilated Cardiomyopathy and Conduction Disease., Sedaghat-Hamedani F,Rebs S,El-Battrawy I,Chasan S,Krause T,Haas J,Zhong R,Liao Z,Xu Q,Zhou X,Zhou X,Akin I,Zitron E,Frey N,Streckfuss-Bömeke K,Kayvanpour E, Int J Mol Sci. November 30, 2021; 22(23):1422-0067.

Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Nav1.5., Galleano I,Harms H,Choudhury K,Khoo K,Delemotte L,Pless SA, Proc Natl Acad Sci U S A. August 17, 2021; 118(33):1091-6490.

The Ubiquitin Ligase TRAIP: Double-Edged Sword at the Replisome., Wu RA,Pellman DS,Walter JC, Trends Cell Biol. February 1, 2021; 31(2):1879-3088.

A revised mechanism of action of hyperaldosteronism-linked mutations in cytosolic domains of GIRK4 (KCNJ5)., Shalomov B,Handklo-Jamal R,Reddy HP,Theodor N,Bera AK,Dascal N, J Physiol. March 1, 2022; 600(6):0022-3751.

Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd., Lee H,Lee H,Sun R,Niehrs C, J Biol Chem. February 1, 2022; 298(2):1083-351X.

Migration of antibiotic resistance genes and evolution of flora structure in the Xenopus tropicalis intestinal tract with combined exposure to roxithromycin and oxytetracycline., Lin X,Xu Y,Xu Y,Han R,Luo W,Zheng L, Sci Total Environ. May 10, 2022; 820:1879-1026.

Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders., Martin M,Vermeiren S,Bostaille N,Eubelen M,Spitzer D,Vermeersch M,Profaci CP,Pozuelo E,Toussay X,Raman-Nair J,Tebabi P,America M,De Groote A,Sanderson LE,Cabochette P,Germano RFV,Torres D,Boutry S,de Kerchove d'Exaerde A,Bellefroid EJ,Phoenix TN,Devraj K,Lacoste B,Daneman R,Liebner S,Vanhollebeke B, Science. February 18, 2022; 375(6582):1095-9203.

16p12.1 Deletion Orthologs are Expressed in Motile Neural Crest Cells and are Important for Regulating Craniofacial Development in Xenopus laevis., Lasser M,Bolduc J,Murphy L,O'Brien C,Lee S,Girirajan S,Lowery LA, Front Genet. January 1, 2022; 13:1664-8021.

Reduced Retinoic Acid Signaling During Gastrulation Induces Developmental Microcephaly., Gur M,Bendelac-Kapon L,Shabtai Y,Pillemer G,Fainsod A, Front Cell Dev Biol. January 1, 2022; 10:2296-634X.

CRISPR/Cas9-Mediated Models of Retinitis Pigmentosa Reveal Differential Proliferative Response of Müller Cells between Xenopus laevis and Xenopus tropicalis., Parain K,Lourdel S,Donval A,Chesneau A,Borday C,Bronchain O,Locker M,Perron M, Cells. February 25, 2022; 11(5):2073-4409.

Pharmacological characterization of a novel negative allosteric modulator of NMDA receptors, UBP792., Sapkota K,Burnell ES,Irvine MW,Fang G,Gawande DY,Dravid SM,Jane DE,Monaghan DT, Neuropharmacology. December 15, 2021; 201:1873-7064.

Multistep mechanism of G-quadruplex resolution during DNA replication., Sato K,Martin-Pintado N,Post H,Altelaar M,Knipscheer P, Sci Adv. September 24, 2021; 7(39):2375-2548.

Homozygous variants in PANX1 cause human oocyte death and female infertility., Wang W,Qu R,Dou Q,Wu F,Wang W,Chen B,Mu J,Zhang Z,Zhang Z,Zhang Z,Zhao L,Zhou Z,Dong J,Zeng Y,Liu R,Du J,Zhu S,Li Q,He L,Jin L,Wang L,Sang Q, Eur J Hum Genet. September 1, 2021; 29(9):1476-5438.

Inhibition of the Aquaporin-1 Cation Conductance by Selected Furan Compounds Reduces Red Blood Cell Sickling., Chow PH,Cox CD,Pei JV,Anabaraonye N,Nourmohammadi S,Henderson SW,Martinac B,Abdulmalik O,Yool AJ, Front Pharmacol. October 1, 2021; 12:1663-9812.

A transepithelial pathway delivers succinate to macrophages, thus perpetuating their pro-inflammatory metabolic state., Fremder M,Kim SW,Khamaysi A,Shimshilashvili L,Eini-Rider H,Park IS,Hadad U,Cheon JH,Ohana E, Cell Rep. August 10, 2021; 36(6):2211-1247.

ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels., Narahari AK,Kreutzberger AJ,Gaete PS,Chiu YH,Leonhardt SA,Medina CB,Jin X,Oleniacz PW,Kiessling V,Barrett PQ,Ravichandran KS,Yeager M,Contreras JE,Tamm LK,Bayliss DA, Elife. January 7, 2021; 10:2050-084X.

The Ribosomal Protein L5 Functions During Xenopus Anterior Development Through Apoptotic Pathways., Schreiner C,Kernl B,Dietmann P,Riegger RJ,Kühl M,Kühl SJ, Front Cell Dev Biol. January 1, 2022; 10:2296-634X.

Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas., Zhong G,Ahimaz P,Edwards NA,Hagen JJ,Faure C,Lu Q,Kingma P,Middlesworth W,Khlevner J,El Fiky M,Schindel D,Fialkowski E,Kashyap A,Forlenza S,Kenny AP,Zorn AM,Shen Y,Chung WK, HGG Adv. July 14, 2022; 3(3):2666-2477.

Cilia-localized GID/CTLH ubiquitin ligase complex regulates protein homeostasis of sonic hedgehog signaling components., Hantel F,Liu H,Fechtner L,Neuhaus H,Ding J,Arlt D,Walentek P,Villavicencio-Lorini P,Gerhardt C,Hollemann T,Pfirrmann T, J Cell Sci. May 1, 2022; 135(9):1477-9137.

Trafficking of the glutamate transporter is impaired in LRRK2-related Parkinson's disease., Iovino L,Giusti V,Pischedda F,Giusto E,Plotegher N,Marte A,Battisti I,Di Iacovo A,Marku A,Piccoli G,Bandopadhyay R,Perego C,Bonifacino T,Bonanno G,Roseti C,Bossi E,Arrigoni G,Bubacco L,Greggio E,Hilfiker S,Civiero L, Acta Neuropathol. July 1, 2022; 144(1):1432-0533.

Distinctive mechanisms of epilepsy-causing mutants discovered by measuring S4 movement in KCNQ2 channels., Edmond MA,Hinojo-Perez A,Wu X,Perez Rodriguez ME,Barro-Soria R, Elife. June 1, 2022; 11:2050-084X.

Predictive assays for craniofacial malformations: evaluation in Xenopus laevis embryos exposed to triadimefon., Battistoni M,Metruccio F,Di Renzo F,Bacchetta R,Menegola E, Arch Toxicol. October 1, 2022; 96(10):0340-5761.

Metalloprotease ADAM9 cleaves ephrin-B ligands and differentially regulates Wnt and mTOR signaling downstream of Akt kinase in colorectal cancer cells., Chandrasekera P,Perfetto M,Lu C,Zhuo M,Bahudhanapati H,Li J,Chen WC,Kulkarni P,Christian L,Liu J,Yien YY,Yu C,Wei S, J Biol Chem. August 1, 2022; 298(8):1083-351X.

Adrenergic receptor signaling induced by Klf15, a regulator of regeneration enhancer, promotes kidney reconstruction., Suzuki N,Kanai A,Suzuki Y,Ogino H,Ochi H, Proc Natl Acad Sci U S A. August 16, 2022; 119(33):1091-6490.

Aquatic Freshwater Vertebrate Models of Epilepsy Pathology: Past Discoveries and Future Directions for Therapeutic Discovery., Williams RE,Mruk K, Int J Mol Sci. August 3, 2022; 23(15):1422-0067.

Functions of block of proliferation 1 during anterior development in Xenopus laevis., Gärtner C,Meßmer A,Dietmann P,Kühl M,Kühl SJ, PLoS One. August 2, 2022; 17(8):1932-6203.

Functional characterization of a novel TP53RK mutation identified in a family with Galloway-Mowat syndrome., Treimer E,Kalayci T,Schumann S,Suer I,Greco S,Schanze D,Schmeisser MJ,Kühl SJ,Zenker M, Hum Mutat. December 1, 2022; 43(12):1098-1004.

Transcription suppression is mediated by the HDAC1-Sin3 complex in Xenopus nucleoplasmic extract., Quaas CE,Lin B,Long DT, J Biol Chem. November 1, 2022; 298(11):1083-351X.

Mink1 regulates spemann organizer cell fate in the xenopus gastrula via Hmga2., Colleluori V,Khokha MK, Dev Biol. March 1, 2023; 495:1095-564X.

The Flavonol Quercitrin Hinders GSK3 Activity and Potentiates the Wnt/β-Catenin Signaling Pathway., Predes D,Maia LA,Matias I,Araujo HPM,Soares C,Barros-Aragão FGQ,Oliveira LFS,Reis RR,Amado NG,Simas ABC,Mendes FA,Gomes FCA,Figueiredo CP,Abreu JG, Int J Mol Sci. October 11, 2022; 23(20):1422-0067.

GABAA receptor function is enhanced by Interleukin-10 in human epileptogenic gangliogliomas and its effect is counteracted by Interleukin-1β., Ruffolo G,Alfano V,Romagnolo A,Zimmer T,Mills JD,Cifelli P,Gaeta A,Morano A,Anink J,Mühlebner A,Vezzani A,Aronica E,Palma E, Sci Rep. October 26, 2022; 12(1):2045-2322.

De novo KCNA6 variants with attenuated KV 1.6 channel deactivation in patients with epilepsy., Salpietro V,Galassi Deforie V,Efthymiou S,O'Connor E,Marcé-Grau A,Maroofian R,Striano P,Zara F,Morrow MM,Reich A,Blevins A,Sala-Coromina J,Accogli A,Fortuna S,Alesandrini M,Au PYB,Singhal NS,Cogne B,Isidor B,Hanna MG,Macaya A,Kullmann DM,Houlden H,Männikkö R, Epilepsia. February 1, 2023; 64(2):1528-1167.

Hnf1b renal expression directed by a distal enhancer responsive to Pax8., Goea L,Buisson I,Bello V,Eschstruth A,Paces-Fessy M,Le Bouffant R,Chesneau A,Cereghini S,Riou JF,Umbhauer M, Sci Rep. November 19, 2022; 12(1):2045-2322.

Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels., Zou X,Wu X,Sampson KJ,Colecraft HM,Larsson HP,Kass RS, Front Physiol. January 1, 2022; 13:1664-042X.

Genome-wide analysis of copy-number variation in humans with cleft lip and/or cleft palate identifies COBLL1, RIC1, and ARHGEF38 as clefting genes., Lansdon LA,Dickinson A,Arlis S,Liu H,Hlas A,Hahn A,Bonde G,Long A,Standley J,Tyryshkina A,Wehby G,Lee NR,Daack-Hirsch S,Mohlke K,Girirajan S,Darbro BW,Cornell RA,Houston DW,Murray JC,Manak JR, Am J Hum Genet. January 5, 2023; 110(1):1537-6605.

HNF1B Alters an Evolutionarily Conserved Nephrogenic Program of Target Genes., Grand K,Stoltz M,Rizzo L,Röck R,Kaminski MM,Salinas G,Getwan M,Naert T,Pichler R,Lienkamp SS, J Am Soc Nephrol. March 1, 2023; 34(3):1533-3450.

Long-QT mutations in KCNE1 modulate the 17β-estradiol response of Kv7.1/KCNE1., Erlandsdotter LM,Giammarino L,Halili A,Nikesjö J,Gréen H,Odening KE,Liin SI, Sci Adv. March 17, 2023; 9(11):2375-2548.

Increased Hemichannel Activity Displayed by a Connexin43 Mutation Causing a Familial Connexinopathy Exhibiting Hypotrichosis with Follicular Keratosis and Hyperostosis., Crouthamel OE,Li L,Dilluvio MT,White TW, Int J Mol Sci. January 22, 2023; 24(3):1422-0067.

The phenotypic spectrum of pathogenic ATP1A1 variants expands: the novel p.P600R substitution causes demyelinating Charcot-Marie-Tooth disease., Cinarli Yuksel F,Nicolaou P,Spontarelli K,Dohrn MF,Rebelo AP,Koutsou P,Georghiou A,Artigas P,Züchner SL,Kleopa KA,Christodoulou K, J Neurol. May 1, 2023; 270(5):1432-1459.

Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome KCNQ1 Variants., Rinné S,Oertli A,Nagel C,Tomsits P,Jenewein T,Kääb S,Kauferstein S,Loewe A,Beckmann BM,Decher N, Int J Mol Sci. January 10, 2023; 24(2):1422-0067.

OXGR1 is a candidate disease gene for human calcium oxalate nephrolithiasis., Majmundar AJ,Widmeier E,Heneghan JF,Daga A,Wu CW,Buerger F,Hugo H,Ullah I,Amar A,Ottlewski I,Braun DA,Jobst-Schwan T,Lawson JA,Zahoor MY,Rodig NM,Tasic V,Nelson CP,Khaliq S,Schönauer R,Halbritter J,Sayer JA,Fathy HM,Baum MA,Shril S,Mane S,Alper SL,Hildebrandt F, Genet Med. March 1, 2023; 25(3):1530-0366.

RAF1 deficiency causes a lethal syndrome that underscores RTK signaling during embryogenesis., Wong S,Tan YX,Loh AYT,Tan KY,Lee H,Lee H,Aziz Z,Nelson SF,Özkan E,Kayserili H,Escande-Beillard N,Reversade B, EMBO Mol Med. May 8, 2023; 15(5):1757-4684.

Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease., Mishra-Gorur K,Barak T,Kaulen LD,Henegariu O,Jin SC,Aguilera SM,Yalbir E,Goles G,Nishimura S,Miyagishima D,Djenoune L,Altinok S,Rai DK,Viviano S,Prendergast A,Zerillo C,Ozcan K,Baran B,Sencar L,Goc N,Yarman Y,Ercan-Sencicek AG,Bilguvar K,Lifton RP,Moliterno J,Louvi A,Yuan S,Deniz E,Brueckner M,Gunel M, Proc Natl Acad Sci U S A. April 18, 2023; 120(16):1091-6490.

The Splicing Factor PTBP1 Represses TP63 γ Isoform Production in Squamous Cell Carcinoma., Taylor W,Deschamps S,Reboutier D,Paillard L,Méreau A,Audic Y, Cancer Res Commun. December 1, 2022; 2(12):2767-9764.

The histone H4K20 methyltransferase SUV4-20H1/KMT5B is required for multiciliated cell differentiation in Xenopus., Angerilli A,Tait J,Berges J,Shcherbakova I,Pokrovsky D,Schauer T,Smialowski P,Hsam O,Mentele E,Nicetto D,Rupp RA, Life Sci Alliance. July 1, 2023; 6(7):2575-1077.

Age-associated DNA methylation changes in Xenopus frogs., Morselli M,Bennett R,Shaidani NI,Horb M,Peshkin L,Pellegrini M, Epigenetics. December 1, 2023; 18(1):1559-2308.

TPX2 expression as a negative predictor of gemcitabine efficacy in pancreatic cancer., Guenther M,Surendran SA,Haas M,Heinemann V,von Bergwelt-Baildon M,Engel J,Werner J,Boeck S,Ormanns S, Br J Cancer. July 1, 2023; 129(1):0007-0920.

Phenotype-genotype relationships in Xenopus sox9 crispants provide insights into campomelic dysplasia and vertebrate jaw evolution., Hossain N,Igawa T,Suzuki M,Suzuki M,Tazawa I,Nakao Y,Hayashi T,Suzuki N,Ogino H, Dev Growth Differ. October 1, 2023; 65(8):1440-169X.

Rare variants in CAPN2 increase risk for isolated hypoplastic left heart syndrome., Blue EE,White JJ,Dush MK,Gordon WW,Wyatt BH,White P,Marvin CT,Helle E,Ojala T,Priest JR,Jenkins MM,Almli LM,Reefhuis J,Pangilinan F,Brody LC,McBride KL,Garg V,Shaw GM,Romitti PA,Nembhard WN,Browne ML,Werler MM,Kay DM,Mital S,Chong JX,Nascone-Yoder NM,Bamshad MJ, HGG Adv. October 12, 2023; 4(4):2666-2477.

Inactivation influences the extent of inhibition of voltage-gated Ca+2 channels by Gem-implications for channelopathies., Allam S,Levenson-Palmer R,Chia Chang Z,Kaur S,Cernuda B,Raman A,Booth A,Dobbins S,Suppa G,Yang J,Buraei Z, Front Physiol. January 1, 2023; 14:1664-042X.

TBC1D32 variants disrupt retinal ciliogenesis and cause retinitis pigmentosa., Bocquet B,Borday C,Erkilic N,Mamaeva D,Donval A,Masson C,Parain K,Kaminska K,Quinodoz M,Perea-Romero I,Garcia-Garcia G,Jimenez-Medina C,Boukhaddaoui H,Coget A,Leboucq N,Calzetti G,Gandolfi S,Percesepe A,Barili V,Uliana V,Delsante M,Bozzetti F,Scholl HP,Corton M,Ayuso C,Millan JM,Rivolta C,Meunier I,Perron M,Kalatzis V, JCI Insight. November 8, 2023; 8(21):2379-3708.

ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer., Pandey A,Cousin H,Horr B,Alfandari D,Alfandari D, Front Cell Dev Biol. January 1, 2023; 11:2296-634X.

Deleterious functional consequences of perfluoroalkyl substances accumulation into the myelin sheath., Butruille L,Jubin P,Martin E,Aigrot MS,Lhomme M,Fini JB,Demeneix B,Stankoff B,Lubetzki C,Zalc B,Remaud S, Environ Int. October 1, 2023; 180:0160-4120.

Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation., Cervino AS,Collodel MG,Lopez IA,Roa C,Hochbaum D,Hukriede NA,Cirio MC, Sci Rep. October 4, 2023; 13(1):2045-2322.

The structural mechanism of dimeric DONSON in replicative helicase activation., Cvetkovic MA,Passaretti P,Butryn A,Reynolds-Winczura A,Kingsley G,Skagia A,Fernandez-Cuesta C,Poovathumkadavil D,George R,Chauhan AS,Jhujh SS,Stewart GS,Gambus A,Costa A, Mol Cell. November 16, 2023; 83(22):1097-4164.

The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH,Spencer Z,Neitzel LR,Nayak A,Loberg MA,Shen C,Kassel SN,Kroh HK,An Z,Anthony CC,Bryant JM,Lawson A,Goldsmith L,Benchabane H,Hansen AG,Li J,D'Souza S,Lebensohn AM,Rohatgi R,Weiss WA,Weiss VL,Williams C,Hong CC,Robbins DJ,Ahmed Y,Lee E,Lee E, Nat Commun. October 5, 2023; 14(1):2041-1723.

Advancements in the use of xenopus oocytes for modelling neurological disease for novel drug discovery., O'Connor EC,Kambara K,Bertrand D, Expert Opin Drug Discov. February 1, 2024; 19(2):1746-045X.

FGFR1 variants contributed to families with tooth agenesis., Yao S,Zhou X,Zhou X,Gu M,Zhang C,Bartsch O,Vona B,Fan L,Ma L,Pan Y, Hum Genomics. October 13, 2023; 17(1):1479-7364.

GRIN2A mutation and early-onset epileptic encephalopathy: personalized therapy with memantine., Pierson TM,Yuan H,Marsh ED,Fuentes-Fajardo K,Adams DR,Markello T,Golas G,Simeonov DR,Holloman C,Tankovic A,Karamchandani MM,Schreiber JM,Mullikin JC,Tifft CJ,Toro C,Boerkoel CF,Traynelis SF,Gahl WA, Ann Clin Transl Neurol. March 1, 2014; 1(3):2328-9503.

Remarkable effect of transdermal nicotine in children with CHRNA4-related autosomal dominant sleep-related hypermotor epilepsy., Lossius K,de Saint Martin A,Myren-Svelstad S,Bjørnvold M,Minken G,Seegmuller C,Valenti Hirsch MP,Chelly J,Steinlein O,Picard F,Brodtkorb E, Epilepsy Behav. April 1, 2020; 105:1525-5069.

Mertk-expressing microglia influence oligodendrogenesis and myelin modelling in the CNS., Nguyen LT,Aprico A,Nwoke E,Walsh AD,Blades F,Avneri R,Martin E,Zalc B,Kilpatrick TJ,Binder MD, J Neuroinflammation. November 6, 2023; 20(1):1742-2094.

Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders., Kaiyrzhanov R,Rad A,Lin SJ,Bertoli-Avella A,Kallemeijn WW,Godwin A,Zaki MS,Huang K,Lau T,Petree C,Efthymiou S,Karimiani EG,Hempel M,Normand EA,Rudnik-Schöneborn S,Schatz UA,Baggelaar MP,Ilyas M,Sultan T,Alvi JR,Ganieva M,Fowler B,Aanicai R,Tayfun GA,Al Saman A,Alswaid A,Amiri N,Asilova N,Shotelersuk V,Yeetong P,Azam M,Babaei M,Monajemi GB,Mohammadi P,Samie S,Banu SH,Pinto Basto J,Kortüm F,Bauer M,Bauer P,Beetz C,Garshasbi M,Issa AH,Eyaid W,Ahmed H,Hashemi N,Hassanpour K,Herman I,Ibrohimov S,Abdul-Majeed BA,Imdad M,Isrofilov M,Kaiyal Q,Khan S,Kirmse B,Koster J,Lourenço CM,Mitani T,Moldovan O,Murphy D,Najafi M,Pehlivan D,Rocha ME,Salpietro V,Schmidts M,Shalata A,Mahroum M,Talbeya JK,Taylor RW,Vazquez D,Vetro A,Waterham HR,Zaman M,Schrader TA,Chung WK,Guerrini R,Lupski JR,Gleeson J,Suri M,Jamshidi Y,Bhatia KP,Vona B,Schrader M,Severino M,Guille M,Tate EW,Varshney GK,Houlden H,Maroofian R, Brain. April 4, 2024; 147(4):1460-2156.

Functional and clinical characterization of a novel homozygous KCNH2 missense variant in the pore region of Kv11.1 leading to a viable but severe long-QT syndrome., Delinière A,Jaupart L,Janin A,Millat G,Boulin T,Andrini O,Chevalier P, Gene. March 1, 2024; 897:1879-0038.

Enhanced Membrane Incorporation of H289Y Mutant GluK1 Receptors from the Audiogenic Seizure-Prone GASH/Sal Model: Functional and Morphological Impacts on Xenopus Oocytes., Díaz-Rodríguez SM,Ivorra I,Espinosa J,Vegar C,Herrero-Turrión MJ,López DE,Gómez-Nieto R,Alberola-Die A, Int J Mol Sci. November 28, 2023; 24(23):1422-0067.

Alcohol induces neural tube defects by reducing retinoic acid signaling and promoting neural plate expansion., Edri T,Cohen D,Shabtai Y,Fainsod A, Front Cell Dev Biol. January 1, 2023; 11:2296-634X.

Selective block of human Kv1.1 channels and an epilepsy-associated gain-of-function mutation by AETX-K peptide., Zhao R,Qasim A,Sophanpanichkul P,Dai H,Nayak M,Sher I,Chill J,Goldstein SAN, FASEB J. January 1, 2024; 38(1):1530-6860.

A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus., Singh AK,Allington G,Viviano S,McGee S,Kiziltug E,Ma S,Zhao S,Mekbib KY,Shohfi JP,Duy PQ,DeSpenza T,Furey CG,Reeves BC,Smith H,Sousa AMM,Cherskov A,Allocco A,Nelson-Williams C,Haider S,Rizvi SRA,Alper SL,Sestan N,Shimelis H,Walsh LK,Lifton RP,Moreno-De-Luca A,Jin SC,Kruszka P,Deniz E,Kahle KT, Brain. April 4, 2024; 147(4):1460-2156.

Genetic models of fibrillinopathies., Summers KM, Genetics. January 3, 2024; 226(1):1943-2631.

SMC5 Plays Independent Roles in Congenital Heart Disease and Neurodevelopmental Disability., O'Brien MP,Pryzhkova MV,Lake EMR,Mandino F,Shen X,Karnik R,Atkins A,Xu MJ,Ji W,Konstantino M,Brueckner M,Ment LR,Khokha MK,Jordan PW, Int J Mol Sci. December 28, 2023; 25(1):1422-0067.

Toward New AQP4 Inhibitors: ORI-TRN-002., Thormann M,Traube N,Yehia N,Koestler R,Galabova G,MacAulay N,Toft-Bertelsen TL, Int J Mol Sci. January 11, 2024; 25(2):1422-0067.

Cannabidiol Strengthening of Gastric Tight Junction Complexes Analyzed in an Improved Xenopus Oocyte Assay., Stein L,Vollstaedt ML,Amasheh S, Membranes (Basel). January 8, 2024; 14(1):2077-0375.

Novel insights into voltage-gated ion channels: Translational breakthroughs in medical oncology., Sakellakis M,Yoon SM,Reet J,Chalkias A, Channels (Austin). December 1, 2024; 18(1):1933-6969.

Ibuprofen-induced multiorgan malformation during embryogenesis in Xenopus laevis (FETAX)., Park MJ,Chae JP,Woo D,Kim JY,Kim JY,Bae YC,Lee JY,Lee JY,Lee SY,Nam EJ,Nam SW, Biochem Biophys Res Commun. April 9, 2024; 703:1090-2104.

Prdm15 acts upstream of Wnt4 signaling in anterior neural development of Xenopus laevis., Saumweber E,Mzoughi S,Khadra A,Werberger A,Schumann S,Guccione E,Schmeisser MJ,Kühl SJ, Front Cell Dev Biol. January 1, 2024; 12:2296-634X.

XPR1: a regulator of cellular phosphate homeostasis rather than a Pi exporter., Burns D,Berlinguer-Palmini R,Werner A, Pflugers Arch. March 20, 2024; :1432-2013.