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XB-PHENO-16426

Xla WT + notch1 ICD [bilateral], Solini GE et al. (2020)

Experiment + Assay: Xla WT + notch1 ICD [bilateral] + NF 18
Background: Xla.J-strainNXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(canotch1) notch1.L
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 18 to NF stage 18  
Anatomical Phenotypes: abnormal neural plate, absent Rohon-Beard neuron
Expression Phenotypes (1):
decreased amount tubb2b.L expression in neural plate
Source: Fig 3 A
Article: XB-ART-56609, PubMed