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XB-PHENO-21514

Xla Wt + Hsa.FGF10 + Hsa.SHH + forelimb amputation, Lin G et al. (2013)

Experiment + Assay: Xla Wt + Hsa.FGF10 + Hsa.SHH + forelimb amputation + juvenile (stained tissue microscopy)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
peptide/protein shh
 NF stage 53 regenerating forelimb
amputation/regeneration  
NF stage 53 forelimb
peptide/protein fgf10
 NF stage 53 regenerating forelimb
Conditions:
Assay Type Assay Stages Antibody
stained tissue microscopy juvenile frog stage  
Anatomical Phenotypes: abnormal digit-joint region , abnormal forelimb digit , abnormal regenerating forelimb , abnormal regenerating forelimb morphology , increased branchiness of regenerating forelimb
Source: Fig.3.E, F
Article: XB-ART-46437, PubMed