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XB-PHENO-22907

Xla Wt + lhx1 + otx2, Rankin SA et al. (2011)

Experiment + Assay: Xla Wt + lhx1 + otx2 + NF11 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection otx2.L otx2.L
otx2.S
 NF stage 4 (8-cell) blastomere V2
mRNA injection lhx1.L lhx1.S
lhx1.L
 NF stage 4 (8-cell) blastomere V2
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 11  
Expression Phenotypes (7):
increased amount gsc.L expression in dorsal endomesoderm
increased amount gsc.L expression in ventral endoderm
mislocalised gsc.L expression in ventral endoderm
increased amount hhex.L expression in dorsal endoderm
mislocalised hhex.L expression in ventral endoderm
increased amount hhex.L expression in ventral endoderm
increased amount otx2.L expression in ventral endoderm
Source: fig.7.c
Article: XB-ART-42631, PubMed