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XB-PHENO-24163

Xla Wt + dyrk1a MO, Blackburn ATM et al. (2019)

Experiment + Assay: Xla Wt + dyrk1a MO + NF40 (immunohistochemistry)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection dyrk1a MO1 dyrk1a (Xla)
 NF stage 4 (8-cell) blastomere V2
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 40 to NF stage 40 Kidney Ab1
immunohistochemistry NF stage 40 to NF stage 40 Kidney Ab2
Anatomical Phenotypes: abnormal distal tubule morphology , abnormal proximal tubule morphology
Human Disease Associations: CAKUT
Source: Fig. S 4 B-D
Article: XB-ART-56082, PubMed