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XB-PHENO-24172

Xla Wt + chd1 MO, Wyatt BH et al. (2021)

Experiment + Assay: Xla Wt + chd1 MO + NF45-46 (stained tissue microscopy)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection chd1 MO1 chd1 (Xla)
 NF stage 1 zygote
Conditions:
Assay Type Assay Stages Antibody
stained tissue microscopy NF stage 45 to NF stage 46  
Anatomical Phenotypes: absent ethmoid bone , decreased size of the Meckel's cartilage , decreased size of the basihyal , decreased size of the ceratohyal
Human Disease Associations: orofacial cleft
Source: Fig. 5 d e
Article: XB-ART-57345, PubMed