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Profile Publications(43)
XB-PERS-2190

Publications By Barry M Gumbiner

Results 1 - 43 of 43 results

Page(s): 1


p53 and microRNA-34 are suppressors of canonical Wnt signaling., Kim NH, Kim HS, Kim NG, Lee I, Choi HS, Li XY, Kang SE, Cha SY, Ryu JK, Na JM, Park C, Kim K, Lee S, Gumbiner BM, Yook JI, Weiss SJ., Sci Signal. November 1, 2011; 4 (197): ra71.


Axial protocadherin (AXPC) regulates cell fate during notochordal morphogenesis., Yoder MD, Gumbiner BM., Dev Dyn. November 1, 2011; 240 (11): 2495-504.          


A protocadherin-cadherin-FLRT3 complex controls cell adhesion and morphogenesis., Chen X, Koh E, Yoder M, Gumbiner BM., PLoS One. December 22, 2009; 4 (12): e8411.                    


Identification of targets of the Wnt pathway destruction complex in addition to beta-catenin., Kim NG, Xu C, Gumbiner BM., Proc Natl Acad Sci U S A. March 31, 2009; 106 (13): 5165-70.


Convergence and extension at gastrulation require a myosin IIB-dependent cortical actin network., Skoglund P, Rolo A, Chen X, Gumbiner BM, Keller R., Development. August 1, 2008; 135 (14): 2435-44.  


The Xenopus Nieuwkoop center and Spemann-Mangold organizer share molecular components and a requirement for maternal Wnt activity., Vonica A, Gumbiner BM., Dev Biol. December 1, 2007; 312 (1): 90-102.            


Structural elements necessary for oligomerization, trafficking, and cell sorting function of paraxial protocadherin., Chen X, Molino C, Liu L, Gumbiner BM., J Biol Chem. November 2, 2007; 282 (44): 32128-37.


Cadherin conformations associated with dimerization and adhesion., Tsuiji H, Xu L, Schwartz K, Gumbiner BM., J Biol Chem. April 27, 2007; 282 (17): 12871-82.


Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating C-cadherin adhesion activity., Chen X, Gumbiner BM., J Cell Biol. July 17, 2006; 174 (2): 301-13.                


Coordinate gene regulation by two different catenins., Gumbiner BM., Dev Cell. June 1, 2005; 8 (6): 795-6.


Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes., Gottardi CJ, Gumbiner BM., J Cell Biol. October 25, 2004; 167 (2): 339-49.                  


Translocation of beta-catenin into the nucleus independent of interactions with FG-rich nucleoporins., Suh EK, Gumbiner BM., Exp Cell Res. November 1, 2003; 290 (2): 447-56.


Zygotic Wnt activity is required for Brachyury expression in the early Xenopus laevis embryo., Vonica A, Gumbiner BM., Dev Biol. October 1, 2002; 250 (1): 112-27.


C-cadherin ectodomain structure and implications for cell adhesion mechanisms., Boggon TJ, Murray J, Chappuis-Flament S, Wong E, Gumbiner BM, Shapiro L., Science. May 17, 2002; 296 (5571): 1308-13.


Cadherin-mediated cell sorting not determined by binding or adhesion specificity., Niessen CM, Gumbiner BM., J Cell Biol. January 21, 2002; 156 (2): 389-399.            


Multiple cadherin extracellular repeats mediate homophilic binding and adhesion., Chappuis-Flament S, Wong E, Hicks LD, Kay CM, Gumbiner BM., J Cell Biol. July 9, 2001; 154 (1): 231-43.                    


A mode of regulation of beta-catenin signaling activity in Xenopus embryos independent of its levels., Guger KA, Gumbiner BM., Dev Biol. July 15, 2000; 223 (2): 441-8.


TCF is the nuclear effector of the beta-catenin signal that patterns the sea urchin animal-vegetal axis., Vonica A, Weng W, Gumbiner BM, Venuti JM., Dev Biol. January 15, 2000; 217 (2): 230-43.


A cell-free assay system for beta-catenin signaling that recapitulates direct inductive events in the early xenopus laevis embryo., Nelson RW, Gumbiner BM., J Cell Biol. October 18, 1999; 147 (2): 367-74.              


Analysis of C-cadherin regulation during tissue morphogenesis with an activating antibody., Zhong Y, Brieher WM, Gumbiner BM., J Cell Biol. January 25, 1999; 144 (2): 351-9.            


Beta-catenin directly induces expression of the Siamois gene, and can initiate signaling indirectly via a membrane-tethered form., Nelson RW, Gumbiner BM., Ann N Y Acad Sci. October 23, 1998; 857 86-98.


Propagation and localization of Wnt signaling., Gumbiner BM., Curr Opin Genet Dev. August 1, 1998; 8 (4): 430-5.


The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn., Yap AS, Niessen CM, Gumbiner BM., J Cell Biol. May 4, 1998; 141 (3): 779-89.                  


Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin., Fagotto F, Glück U, Gumbiner BM., Curr Biol. February 12, 1998; 8 (4): 181-90.


Antagonism of cell adhesion by an alpha-catenin mutant, and of the Wnt-signaling pathway by alpha-catenin in Xenopus embryos., Sehgal RN, Gumbiner BM, Reichardt LF., J Cell Biol. November 17, 1997; 139 (4): 1033-46.                      


The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation., Zeng L, Fagotto F, Zhang T, Hsu W, Vasicek TJ, Perry WL, Lee JJ, Tilghman SM, Gumbiner BM, Costantini F., Cell. July 11, 1997; 90 (1): 181-92.        


Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function., Yap AS, Brieher WM, Pruschy M, Gumbiner BM., Curr Biol. May 1, 1997; 7 (5): 308-15.


Adenomatous polyposis coli tumor suppressor protein has signaling activity in Xenopus laevis embryos resulting in the induction of an ectopic dorsoanterior axis., Vleminckx K, Wong E, Guger K, Rubinfeld B, Polakis P, Gumbiner BM., J Cell Biol. January 27, 1997; 136 (2): 411-20.            


A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier., Wong V, Gumbiner BM., J Cell Biol. January 27, 1997; 136 (2): 399-409.            


Induction of the primary dorsalizing center in Xenopus by the Wnt/GSK/beta-catenin signaling pathway, but not by Vg1, Activin or Noggin., Fagotto F, Guger K, Gumbiner BM., Development. January 1, 1997; 124 (2): 453-60.


Lateral dimerization is required for the homophilic binding activity of C-cadherin., Brieher WM, Yap AS, Gumbiner BM., J Cell Biol. October 1, 1996; 135 (2): 487-96.


Binding to cadherins antagonizes the signaling activity of beta-catenin during axis formation in Xenopus., Fagotto F, Funayama N, Gluck U, Gumbiner BM., J Cell Biol. March 1, 1996; 132 (6): 1105-14.                


beta-Catenin has Wnt-like activity and mimics the Nieuwkoop signaling center in Xenopus dorsal-ventral patterning., Guger KA, Gumbiner BM., Dev Biol. November 1, 1995; 172 (1): 115-25.


Signal transduction of beta-catenin., Gumbiner BM., Curr Opin Cell Biol. October 1, 1995; 7 (5): 634-40.


Disruption of gastrulation movements in Xenopus by a dominant-negative mutant for C-cadherin., Lee CH, Gumbiner BM., Dev Biol. October 1, 1995; 171 (2): 363-73.


Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling., Funayama N, Fagotto F, McCrea P, Gumbiner BM., J Cell Biol. March 1, 1995; 128 (5): 959-68.


Beta-catenin localization during Xenopus embryogenesis: accumulation at tissue and somite boundaries., Fagotto F, Gumbiner BM., Development. December 1, 1994; 120 (12): 3667-79.                  


Regulation of C-cadherin function during activin induced morphogenesis of Xenopus animal caps., Brieher WM, Gumbiner BM., J Cell Biol. July 1, 1994; 126 (2): 519-27.


Selective disruption of E-cadherin function in early Xenopus embryos by a dominant negative mutant., Levine E, Lee CH, Kintner C, Gumbiner BM., Development. April 1, 1994; 120 (4): 901-9.


Induction of a secondary body axis in Xenopus by antibodies to beta-catenin., McCrea PD, Brieher WM, Gumbiner BM., J Cell Biol. October 1, 1993; 123 (2): 477-84.


Catenins as mediators of the cytoplasmic functions of cadherins., Gumbiner BM, McCrea PD., J Cell Sci Suppl. January 1, 1993; 17 155-8.


The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties., Peifer M, McCrea PD, Green KJ, Wieschaus E, Gumbiner BM., J Cell Biol. August 1, 1992; 118 (3): 681-91.


Purification of a 92-kDa cytoplasmic protein tightly associated with the cell-cell adhesion molecule E-cadherin (uvomorulin). Characterization and extractability of the protein complex from the cell cytostructure., McCrea PD, Gumbiner BM., J Biol Chem. March 5, 1991; 266 (7): 4514-20.

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