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Profile Publications(42)
XB-PERS-1295


Pierre D McCrea

Position

Professor

Research Description

Our overall goal is to understand the cellular and developmental functions of catenins.
1) Reveal the roles of additional catenins in the canonical-Wnt pathway, as well as non-canonical Wnt pathways in animal development.
2) Examine the developmental functions of lesser understood catenins such as p120-catenin, ARVCF-catenin and delta-catenin. Aim (2) occupies most of our laboratory's current efforts. For example, we are working upon delta-catenin in the context of shaping neurons/ dendrites, which has implications for both normal development (e.g. brain function) and disease processes.

Lab Memberships

McCrea Lab (Principal Investigator/Director)