Elly M Tanaka
Molecular cell biology of limb and spinal cord regeneration as well as the evolution of regeneration using Axolotl, Mouse, and sometimes also Xenopus models. Our group seeks to understand the cellular mechanisms underlying salamander limb and spinal cord regeneration as a model for how successful regeneration occurs in a vertebrate. This model acts as a starting point to rigorously investigate how mammals such as mice have lost regeneration capabilities over evolution. In addition, these studies act as a springboard to design novel strategies for regenerating or replacing mammalian tissues. Toward that end we have engineered three-dimensional spinal cord tissue from mouse embryonic stem cells and retinal pigment epithelia from human embryonic stem cells.
Lab MembershipsTanaka Lab (Principal Investigator/Director)
Research Institute of Molecular Pathology