The gene flcn in Strongylocentrotus purpuratus encodes a protein that functions as a tumor suppressor and is involved in cell growth regulation. It is expressed in the gut and immune cells. The protein...[+]

The gene flcn in Strongylocentrotus purpuratus encodes a protein that functions as a tumor suppressor and is involved in cell growth regulation. It is expressed in the gut and immune cells. The protein is localized in the cytoplasm and functions in mTOR signaling pathways. [-]

             Birt-Hogg-Dube syndrome

          BIRT-HOGG-DUBE SYNDROME; BHD
          PNEUMOTHORAX, PRIMARY SPONTANEOUS
          POTOCKI-LUPSKI SYNDROME; PTLS

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD