Based on Echinobase, the sycp3 gene in Strongylocentrotus purpuratus encodes a synaptonemal complex protein essential for meiosis, specifically involved in chromosome synapsis and recombination during ...[+]

Based on Echinobase, the sycp3 gene in Strongylocentrotus purpuratus encodes a synaptonemal complex protein essential for meiosis, specifically involved in chromosome synapsis and recombination during gametogenesis. The sycp3 protein functions as a structural component of the synaptonemal complex, facilitating chromosome pairing and crossover formation. It is expressed in germ cells, particularly in the testes and ovaries, and is crucial for proper chromosome segregation during meiosis. The protein localizes to the synaptonemal complex and is required for accurate chromosome segregation and genetic diversity. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD