Xenbase Image ID: 145825

Fie. 8. Spatial pattet·ns of int.lgrin {33 mRNA expression analyzed by whole mount in situ hybridization. Whole n10unt in situ hybridizations reveal a more restricted pattern of integrin 13, mRNA expression in comparison to that of /31 • (A) Side view of a stage 17 neurula; note staining in a line of cells in the neural groove at the anterior end (arrow). (B) Dorsal view of the same embryo in (A), staining in the neural groove (arrow) and neural folds (arrowheads). (C) Dorsal view of a stage 18 neurula; {J3 mRNA expression in the neural groove (arrow) decreases beginning at the posterior end of the embryo and proceeding anteriorly. Arrowheads indicate staining along the neural folds. (D) Side view of a stage 30 embryo that has begun to express /33 mRNA in a subset ofventral blood island cells (arrow). (E) Side view of a stage :32/33 tailbud embryo before the onset of blood circulation; note the broadly distributed mass of stained ventral cells (arrows). (F} Stage 33/34 embryo after circulation has begun. The /13-positive cells are now found scattered throughout the embryo. (G, H) Stage 35/36 and 37/38 embryos have an increased number of cells expressing Ps associated with major blood vessels. (H) Note the line of stained cells along dorsal blood vessels (arrowheads) and in the regi()n o£ the heart (arrow}. Image published in: Ransom DG et al. (1993) Copyright © 1993. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue itgb3.L cd61, gp3a X. laevis Sometime during NF stage 17 to NF stage 18 neural groove neural fold itgb3.L cd61, gp3a X. laevis Throughout NF stage 29 and 30 ventral blood island itgb3.L cd61, gp3a X. laevis Sometime during NF stage 33 and 34 to NF stage 37 and 38 blood Image source: Published Larger Image Printer Friendly View

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