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XB-IMG-153789

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Figure 5. Effects of Eya1 knockdown on target genes. Tail bud (A–G) and neural plate (H–I) stage embryos after unilateral injection of Eya1-MO1+2. In each case, lacZ was co-injected as a lineage tracer and panels A1–G1 show the control (un-injected) side and A2–G2 show the injected side (lacZ staining out of frame in most specimens). The injected side is positioned to the right in H–J, as marked by blue lacZ staining. Arrows and arrowheads mark reductions in marker gene expression in placodal and non-placodal derivatives, respectively.

Image published in: Riddiford N and Schlosser G (2016)

© 2016, Riddiford et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license

GeneSynonymsSpeciesStage(s)Tissue
atoh1.Lath1, bhlha14, hath1, math-1, math1, xath-1X. laevisThroughout NF stage 28hindbrain
neurogenic placode
otic vesicle
gfi1.Lgfi1aX. laevisThroughout NF stage 28neurogenic placode
trigeminal placode
lateral line ganglion
ventral blood island
hes5.4.Lhes8X. laevisThroughout NF stage 28trigeminal placode
trigeminal ganglion
trigeminal nerve
retina
olfactory placode
eye
hes5.6.LX. laevisThroughout NF stage 28retina
eye
hindbrain
midbrain
forebrain
telencephalon
trigeminal placode
trigeminal ganglion
trigeminal nerve
pou4f4.LBrn3d, pou4f1.2X. laevisThroughout NF stage 28trigeminal placode
trigeminal ganglion
trigeminal nerve
otic vesicle
neurogenic placode
tlx1.Lhox11, hox11-a, LOC108697427, Xhox11, XHox11L2X. laevisThroughout NF stage 28trigeminal placode
trigeminal ganglion
otic vesicle
neurogenic placode
heart
primary heart field
secondary heart field
isl2.Lislet-2, islet2b, LOC108711275X. laevisThroughout NF stage 28trigeminal placode
trigeminal ganglion
trigeminal nerve
otic vesicle
neurogenic placode
spinal cord
neurog1.Lneurod3, neurogenin, neurogenin 1, neurogenin-1, neurogenin1, ngn, ngn1X. laevisThroughout NF stage 18chordal neural plate
chordal neural plate border
Rohon-Beard neuron
neurogenic placode
sox2.Sanop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2X. laevisThroughout NF stage 18neural plate
pre-chordal neural plate
chordal neural plate
neural groove
eye primordium
optic vesicle
sox3.LSry, Xlsox3, xSox3, Xtsox3X. laevisThroughout NF stage 18neural plate
pre-chordal neural plate
chordal neural plate
optic vesicle
eye primordium

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