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XB-IMG-158179

Xenbase Image ID: 158179


FIGUTRE 8. Genes repressing or being downregulated during cancer development/progression show varied expression patterns in Xenopus embryos. A, spatial expression patterns were examined with WMISH. Embryos at the same stages as shown in Fig. 6 were used and presented in the same way as in Fig. 6. A, anterior; ad, adenohypophysial placode; ba, branchial arch; cg, cement gland; cgp, cement gland primordium; ep, epidermis; ev, ear vesicle; ey, eye; fb, forebrain; hb, hindbrain; le, lens; mb, midbrain; mhb, midbrain-hindbrain boundary; nc, notochord; nu, neuron; np, neural plate; nt, neural tube; P, posterior; pn, pronephros; pm, paraxial mesoderm; ps, posterior somite; sm, somite; tg, trigeminal nerve. B, summary of the relatedness of gene expression/function in cancer and their expression.

Image published in: Zhang Z et al. (2017)

Copyright © 2017. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

GeneSynonymsSpeciesStage(s)Tissue
apc.SxapcX. laevisSometime during NF stage 15 to NF stage 20neuroectoderm
neural plate
apc.SxapcX. laevisSometime during NF stage 26 to NF stage 32brain
forebrain
midbrain
hindbrain
central nervous system
eye
branchial arch
trigeminal ganglion
head
pharyngeal region
neurogenic placode
arid1a.SLOC108708921X. laevisSometime during NF stage 15 to NF stage 20neuroectoderm
neural plate
neural tube
arid1a.SLOC108708921X. laevisSometime during NF stage 26 to NF stage 32brain
forebrain
midbrain
hindbrain
central nervous system
eye
branchial arch
head
pharyngeal region
intermediate mesoderm
axin1.SxAxin, axin, fusedX. laevisSometime during NF stage 15 to NF stage 20 
axin1.SxAxin, axin, fusedX. laevisSometime during NF stage 26 to NF stage 32 
brms1.LX. laevisSometime during NF stage 15 to NF stage 20 
brms1.LX. laevisSometime during NF stage 26 to NF stage 32 
casp9.SxCaspase-9, caspase-9, caspase 9, caspase9, iCasp9X. laevisSometime during NF stage 15 to NF stage 20neuroectoderm
neural plate
casp9.SxCaspase-9, caspase-9, caspase 9, caspase9, iCasp9X. laevisSometime during NF stage 26 to NF stage 32brain
forebrain
midbrain
hindbrain
head
eye
pharyngeal region
somite
central nervous system
cdkn1a.Lp16Xic2, p21, cip1X. laevisSometime during NF stage 15 to NF stage 20cement gland primordium
ectoderm
cdkn1a.Lp16Xic2, p21, cip1X. laevisSometime during NF stage 26 to NF stage 32cement gland
somite
eye
otic vesicle
lens placode
cdkn1b.Sp16Xic3, kip1, men4, cdkn4, men1b, p27kip1, p17Xic3X. laevisSometime during NF stage 15 to NF stage 20neural plate
cdkn1b.Sp16Xic3, kip1, men4, cdkn4, men1b, p27kip1, p17Xic3X. laevisSometime during NF stage 26 to NF stage 32 
cdkn2b.Lp15, mts2, tp15, cdk4l, ink4b, p15ink4bX. laevisSometime during NF stage 15 to NF stage 20neural plate
cdkn2b.Lp15, mts2, tp15, cdk4l, ink4b, p15ink4bX. laevisSometime during NF stage 26 to NF stage 32head
pharyngeal region
chfr.LX. laevisSometime during NF stage 15 to NF stage 20neural plate
neuroectoderm
chfr.LX. laevisSometime during NF stage 26 to NF stage 32brain
forebrain
midbrain
hindbrain
central nervous system
head
pharyngeal region
otic vesicle
eye
paraxial mesoderm
dlc1.Srhogap7X. laevisSometime during NF stage 15 to NF stage 20neuroectoderm
neural plate
dlc1.Srhogap7X. laevisSometime during NF stage 26 to NF stage 32 
dmbt1.Sgp340, muclin, hensin, gp-340, glycoprotein 340, salivary agglutininX. laevisSometime during NF stage 15 to NF stage 20ectoderm
dmbt1.Sgp340, muclin, hensin, gp-340, glycoprotein 340, salivary agglutininX. laevisSometime during NF stage 26 to NF stage 32 
gas1.LX. laevisSometime during NF stage 15 to NF stage 20neuroectoderm
neural plate
paraxial mesoderm
epidermis
gas1.LX. laevisSometime during NF stage 26 to NF stage 32brain
midbrain
hindbrain
central nervous system
somite
otic vesicle
head
hexim1.LX. laevisSometime during NF stage 15 to NF stage 20neuroectoderm
neural plate
hexim1.LX. laevisSometime during NF stage 26 to NF stage 32pronephric nephrostome
head
eye
pharyngeal region
tail bud
otic vesicle
brain
hic1.LX. laevisSometime during NF stage 15 to NF stage 20neuron
neuroectoderm
hic1.LX. laevisSometime during NF stage 26 to NF stage 32trigeminal ganglion
notochord
mgmt.LX. laevisSometime during NF stage 15 to NF stage 20 
mgmt.LX. laevisSometime during NF stage 26 to NF stage 32 
pbrm1.Lpb1X. laevisSometime during NF stage 15 to NF stage 20neuroectoderm
neural plate
pbrm1.Lpb1X. laevisSometime during NF stage 26 to NF stage 32central nervous system
brain
eye
forebrain
midbrain
hindbrain
pharyngeal region
otic vesicle
pdcd4.Lh731X. laevisSometime during NF stage 15 to NF stage 20neuroectoderm
neural plate
ectoderm
pdcd4.Lh731X. laevisSometime during NF stage 26 to NF stage 32eye
lens placode
midbrain-hindbrain boundary
perp.Sthw, kcp1, pigpc1, krtcap1X. laevisSometime during NF stage 15 to NF stage 20neuroectoderm
perp.Sthw, kcp1, pigpc1, krtcap1X. laevisSometime during NF stage 26 to NF stage 32 
phlpp1.Sscop, phlpp, plekhe1X. laevisSometime during NF stage 15 to NF stage 20 
phlpp1.Sscop, phlpp, plekhe1X. laevisSometime during NF stage 26 to NF stage 32 
pten.LX. laevisSometime during NF stage 15 to NF stage 20neuroectoderm
neural plate
ectoderm
pten.LX. laevisSometime during NF stage 26 to NF stage 32head
brain
eye
pharyngeal region
central nervous system
otic vesicle
branchial arch
forebrain
midbrain
hindbrain
st13.SX. laevisSometime during NF stage 15 to NF stage 20neuroectoderm
neural plate
st13.SX. laevisSometime during NF stage 26 to NF stage 32brain
hindbrain
central nervous system
eye
head
pharyngeal region
otic vesicle
midbrain
intermediate mesoderm
tet2.LX. laevisSometime during NF stage 15 to NF stage 20 
tet2.LX. laevisSometime during NF stage 26 to NF stage 32brain
forebrain
midbrain
midbrain-hindbrain boundary
central nervous system
head
eye
pharyngeal region
tgfbr1.Saat5, alk5, skr4, alk-5, lds1a, lds2a, tgfr-1, acvrlk4, xTrR-1, TrR-1X. laevisSometime during NF stage 15 to NF stage 20 
tgfbr1.Saat5, alk5, skr4, alk-5, lds1a, lds2a, tgfr-1, acvrlk4, xTrR-1, TrR-1X. laevisSometime during NF stage 26 to NF stage 32 
tp53.Lp53, Xp53, Trp248, Xrel3, tumor suppressor p53X. laevisSometime during NF stage 15 to NF stage 20neuroectoderm
neural plate
tp53.Lp53, Xp53, Trp248, Xrel3, tumor suppressor p53X. laevisSometime during NF stage 26 to NF stage 32brain
midbrain
hindbrain
midbrain-hindbrain boundary
head
eye
pharyngeal region
central nervous system
otic vesicle
branchial arch
presomitic mesoderm
tp73.LxP73, LOC108696624X. laevisSometime during NF stage 15 to NF stage 20 
tp73.LxP73, LOC108696624X. laevisSometime during NF stage 26 to NF stage 32 
tp53bp2.LX. laevisSometime during NF stage 15 to NF stage 20neuroectoderm
neural plate
cement gland primordium
tp53bp2.LX. laevisSometime during NF stage 26 to NF stage 32brain
forebrain
midbrain
midbrain-hindbrain boundary
head
eye
pharyngeal region
pronephric mesenchyme
otic vesicle
central nervous system
txnip.LX. laevisSometime during NF stage 15 to NF stage 20 
txnip.LX. laevisSometime during NF stage 26 to NF stage 32somite
ventral mesoderm

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