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XB-IMG-177049

Xenbase Image ID: 177049


Fig 3 RAR-selective agonist TTNPB modulates expression of genes identified by RNA-seq. (A-P) WISH from embryos treated at stage 6/7 with 1 μM TTNPB or control vehicle (0.1% ethanol). (A-D,I-L) Control expression of znf703, znf503, kremen2, mamdc2, skida1, nkx6-2, dhh and cyp26a1. (E-H,M-P) TTNPB expands expression of these genes. All embryos are shown in vegetal view at stage 10.5/11 with dorsal lip at the top. N, number of embryos scored in the experiment; 100% of embryos displayed the phenotype shown.

Image published in: Janesick A et al. (2018)

Copyright © 2018. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

GeneSynonymsSpeciesStage(s)Tissue
znf703.Lznf703-a, znf703-bX. laevisSometime during NF stage 10.5 to NF stage 11mesoderm
dorso-lateral marginal zone
ventro-lateral marginal zone
ventral marginal zone
znf503.LX. laevisSometime during NF stage 10.5 to NF stage 11ventral marginal zone
ventro-lateral marginal zone
dorso-lateral marginal zone
kremen2.Skrm2, kremen 2X. laevisSometime during NF stage 10.5 to NF stage 11ventral marginal zone
ventro-lateral marginal zone
dorso-lateral marginal zone
mamdc2.LMAM domain protein, gene B, genebX. laevisSometime during NF stage 10.5 to NF stage 11ventral marginal zone
ventro-lateral marginal zone
dorso-lateral marginal zone
nkx6-2.Lnkx6.2X. laevisSometime during NF stage 10.5 to NF stage 11dorsal marginal zone
upper blastopore lip
dhh.Lcephalic hedgehog, chh, x-chh, dhh-1, desert hedgehog, Xchh, dhh-a, dhh-bX. laevisSometime during NF stage 10.5 to NF stage 11marginal zone
blastopore lip
cyp26a1.SxCYP26, XCYP26A1, cyp26, RACE, retinoic acid converting enzymeX. laevisSometime during NF stage 10.5 to NF stage 11circumblastoporal collar
mesoderm

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