Xenbase Image ID: 26300

Figure 4. A: Comparative in situ hybridization analysis of X. tropicalis Ngn1, Ngn2, Ngn3, and X. laevis Ngn1, Ngnr-1, and Ngn3 in stage 30 embryos. Probes are indicated on the left of each line of embryos. Shown: first panel, lateral view, anterior to the left; second panel, close-up of the head region; third panel dorsal view of head region; fourth panel, transverse section at the level of the retina; fifth panel, transverse section at the level of the otic vesicle. The transversal sections were performed with embryos stained for both Ngn (dark blue) and N-tubulin (red). VII, facial epibranchial placode; IX, glossopharyngeal epibranchial placode; X1, first vagal epibranchial placode; X2, second vagal epibranchial placode; X3, third vagal epibranchial placode; hb, hindbrain; mb, midbrain; nc, notochord; op, olfactory placode; vOT, otic vesicle; tg, trigeminal placode; pg, pineal gland; pP, posterior lateral line placode; pM, middle lateral line placode; pAD, anterodorsal lateral line placode; r, retina. B: Double in situ hybridization of stage 30 X. laevis embryos with Ngn1, Ngnr-1, Ngn3 (dark blue) and the mid-hindbrain boundary marker En-2 (red) or with the ventral forebrain marker Nkx2.1 (red) (transversal section). Black arrowhead marks the expression of Ngn3 in the ventral forebrain. Image published in: Nieber F et al. (2009) Copyright © 2009. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue neurog1 neurod3, neurogenin, neurogenin 1, neurogenin-1, neurogenin1, ngn, ngn1 X. tropicalis Throughout NF stage 29 and 30 midbrain trigeminal placode hindbrain lateral line placode otic vesicle epibranchial placode spinal cord ventricular zone pineal gland olfactory placode anterior dorsal lateral line middle lateral line facial nerve glossopharyngeal nerve vagus nerve posterior neurog2.L atoh4, neurog2-a, neurog2-b, neurogenin 2, neurogenin-2, neurogenin-related-1, neurogenin2, ngn-2, ngn2, ngnr, ngnr 1a, Ngnr-1, Ngnr1, X-ngnr-1, xngn2, Xngnr-1, XNgnr1 X. laevis Throughout NF stage 29 and 30 forebrain retinal neural layer spinal cord hindbrain epibranchial placode midbrain vagus nerve pineal gland olfactory placode trigeminal placode facial nerve glossopharyngeal nerve neurog2 atoh4, neurog2-a, neurog2-b, neurogenin 2, neurogenin-2, neurogenin-related-1, neurogenin2, ngn-2, ngn2, ngnr, ngnr 1a, Ngnr-1, Ngnr1, X-ngnr-1, xngn2, Xngnr-1, XNgnr1 X. tropicalis Throughout NF stage 29 and 30 hindbrain epibranchial placode brain spinal cord midbrain ventricular zone retinal neural layer neurog3.S atoh5, bhlha7, math4b, neurogenin-3, neurogenin3, ngn-3, ngn3 X. laevis Throughout NF stage 29 and 30 spinal cord hindbrain neurog3 atoh5, bhlha7, math4b, neurogenin-3, neurogenin3, ngn-3, ngn3 X. tropicalis Throughout NF stage 29 and 30 hindbrain spinal cord neurog1.L neurod3, neurogenin, neurogenin 1, neurogenin-1, neurogenin1, ngn, ngn1 X. laevis Throughout NF stage 29 and 30 midbrain trigeminal placode lateral line placode facial nerve glossopharyngeal nerve vagus nerve hindbrain otic vesicle olfactory pit pineal gland tubb2b N-Tub, n-tubulin, NBT, neural beta-tubulin, NST, ntubulin, Xn-tubulin X. tropicalis Throughout NF stage 29 and 30 midbrain trigeminal placode tubb2b.S N-Tub, n-tubulin, NBT, neural beta-tubulin, NST, ntubulin, Xn-tubulin X. laevis Throughout NF stage 29 and 30 retina otic vesicle midbrain trigeminal placode en2.L En-2, en2-a, en2-b, eng2, engrailed 2, engrailed homolog 2, engrailed-2, maben, xen2 X. laevis Throughout NF stage 29 and 30 midbrain-hindbrain boundary nkx2-1.L nkx2.1, titf1, ttf1, Xnkx-2.1, xnkx2-1 X. laevis Throughout NF stage 29 and 30 forebrain ventral Image source: Published Larger Image Printer Friendly View

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