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The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis. , Guo Y., Dev Biol. May 1, 2019; 449 (1): 1-13.
Id genes are essential for early heart formation. , Cunningham TJ., Genes Dev. July 1, 2017; 31 (13): 1325-1338.
The CapZ interacting protein Rcsd1 is required for cardiogenesis downstream of Wnt11a in Xenopus laevis. , Hempel A., Dev Biol. April 1, 2017; 424 (1): 28-39.
CUG-BP, Elav-like family member 1 (CELF1) is required for normal myofibrillogenesis, morphogenesis, and contractile function in the embryonic heart. , Blech-Hermoni Y., Dev Dyn. August 1, 2016; 245 (8): 854-73.
Direct nkx2-5 transcriptional repression of isl1 controls cardiomyocyte subtype identity. , Dorn T., Stem Cells. April 1, 2015; 33 (4): 1113-29.
Tcf21 regulates the specification and maturation of proepicardial cells. , Tandon P ., Development. June 1, 2013; 140 (11): 2409-21.
Dissociation of cardiogenic and postnatal myocardial activities of GATA4. , Gallagher JM., Mol Cell Biol. June 1, 2012; 32 (12): 2214-23.
Tbx5 overexpression favors a first heart field lineage in murine embryonic stem cells and in Xenopus laevis embryos. , Herrmann F., Dev Dyn. December 1, 2011; 240 (12): 2634-45.
Focal adhesion kinase is essential for cardiac looping and multichamber heart formation. , Doherty JT., Genesis. August 1, 2010; 48 (8): 492-504.
Early activation of FGF and nodal pathways mediates cardiac specification independently of Wnt/beta-catenin signaling. , Samuel LJ., PLoS One. October 28, 2009; 4 (10): e7650.
Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5. , Espinoza-Lewis RA., Dev Biol. March 15, 2009; 327 (2): 376-85.
Cardiac differentiation in Xenopus requires the cyclin-dependent kinase inhibitor, p27Xic1. , Movassagh M., Cardiovasc Res. August 1, 2008; 79 (3): 436-47.
IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis. , Zhu W., Nature. July 17, 2008; 454 (7202): 345-9.
A crucial role of a high mobility group protein HMGA2 in cardiogenesis. , Monzen K., Nat Cell Biol. May 1, 2008; 10 (5): 567-74.
HIF-1alpha signaling upstream of NKX2.5 is required for cardiac development in Xenopus. , Nagao K., J Biol Chem. April 25, 2008; 283 (17): 11841-9.
Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart. , Wu SM ., Cell. December 15, 2006; 127 (6): 1137-50.
Retinoic acid signaling is essential for formation of the heart tube in Xenopus. , Collop AH., Dev Biol. March 1, 2006; 291 (1): 96-109.
Wnt11 facilitates embryonic stem cell differentiation to Nkx2.5-positive cardiomyocytes. , Terami H., Biochem Biophys Res Commun. December 17, 2004; 325 (3): 968-75.
Myocardin expression is regulated by Nkx2.5, and its function is required for cardiomyogenesis. , Ueyama T., Mol Cell Biol. December 1, 2003; 23 (24): 9222-32.
Csm, a cardiac-specific isoform of the RNA helicase Mov10l1, is regulated by Nkx2.5 in embryonic heart. , Ueyama T., J Biol Chem. August 1, 2003; 278 (31): 28750-7.
Chamber-specific differentiation of Nkx2.5-positive cardiac precursor cells from murine embryonic stem cells. , Hidaka K., FASEB J. April 1, 2003; 17 (6): 740-2.
Nkx2.5 homeoprotein regulates expression of gap junction protein connexin 43 and sarcomere organization in postnatal cardiomyocytes. , Kasahara H., J Mol Cell Cardiol. March 1, 2003; 35 (3): 243-56.
Cardiomyogenic differentiation in cardiac myxoma expressing lineage-specific transcription factors. , Kodama H., Am J Pathol. August 1, 2002; 161 (2): 381-9.
Csx/ Nkx2-5 is required for homeostasis and survival of cardiac myocytes in the adult heart. , Toko H., J Biol Chem. July 5, 2002; 277 (27): 24735-43.
The Polycomb-group gene Rae28 sustains Nkx2.5/ Csx expression and is essential for cardiac morphogenesis. , Shirai M., J Clin Invest. July 1, 2002; 110 (2): 177-84.
Differential regulation of the cardiac sodium calcium exchanger promoter in adult and neonatal cardiomyocytes by Nkx2.5 and serum response factor. , Müller JG., J Mol Cell Cardiol. July 1, 2002; 34 (7): 807-21.
Embryonic expression of an Nkx2-5/Cre gene using ROSA26 reporter mice. , Moses KA., Genesis. December 1, 2001; 31 (4): 176-80.
BMP signaling regulates Nkx2-5 activity during cardiomyogenesis. , Jamali M., FEBS Lett. November 30, 2001; 509 (1): 126-30.
The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation. , Yamagishi H., Dev Biol. November 15, 2001; 239 (2): 190-203.
Nkx2-5 activity is essential for cardiomyogenesis. , Jamali M., J Biol Chem. November 9, 2001; 276 (45): 42252-8.
Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation. , Hiroi Y., Nat Genet. July 1, 2001; 28 (3): 276-80.
Characterization of homo- and heterodimerization of cardiac Csx/ Nkx2.5 homeoprotein. , Kasahara H., J Biol Chem. February 16, 2001; 276 (7): 4570-80.
Functional analyses of three Csx/ Nkx-2.5 mutations that cause human congenital heart disease. , Zhu W., J Biol Chem. November 10, 2000; 275 (45): 35291-6.
A role for GATA-4/5/6 in the regulation of Nkx2.5 expression with implications for patterning of the precardiac field. , Jiang Y., Dev Biol. December 1, 1999; 216 (1): 57-71.
Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/ Nkx-2.5 and GATA-4. , Monzen K., Mol Cell Biol. October 1, 1999; 19 (10): 7096-105.
The cardiac homeobox gene Csx/ Nkx2.5 lies genetically upstream of multiple genes essential for heart development. , Tanaka M., Development. March 1, 1999; 126 (6): 1269-80.
CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway. , Zou Y., Development. February 1, 1997; 124 (4): 793-804.
Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. , Chen JN ., Development. December 1, 1996; 122 (12): 3809-16.
Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription. , Chen CY ., Mol Cell Biol. November 1, 1996; 16 (11): 6372-84.
Activation of the cardiac alpha-actin promoter depends upon serum response factor, Tinman homologue, Nkx-2.5, and intact serum response elements. , Chen CY ., Dev Genet. January 1, 1996; 19 (2): 119-30.
Induction of avian cardiac myogenesis by anterior endoderm. , Schultheiss TM., Development. December 1, 1995; 121 (12): 4203-14.