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Summary Anatomy Item Literature (350) Expression Attributions Wiki
XB-ANAT-1675

Papers associated with cardiac myocyte (and kcnh2)

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Polyunsaturated fatty acid analogues differentially affect cardiac NaV, CaV, and KV channels through unique mechanisms., Bohannon BM., Elife. March 24, 2020; 9                                                               


Non-sedating antihistamines block G-protein-gated inwardly rectifying K+ channels., Chen IS., Br J Pharmacol. September 1, 2019; 176 (17): 3161-3179.


Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are IKr blockers with proarrhythmic effects in vitro and in vivo., Baburin I., Pharmacol Res. May 1, 2018; 131 150-163.


Regulation of human cardiac potassium channels by full-length KCNE3 and KCNE4., Abbott GW., Sci Rep. December 6, 2016; 6 38412.              


Eag Domains Regulate LQT Mutant hERG Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes., Liu QN., PLoS One. April 22, 2015; 10 (4): e0123951.                


Concatenated hERG1 tetramers reveal stoichiometry of altered channel gating by RPR-260243., Wu W., Mol Pharmacol. January 1, 2015; 87 (3): 401-9.


Concerted all-or-none subunit interactions mediate slow deactivation of human ether-à-go-go-related gene K+ channels., Thomson SJ., J Biol Chem. August 22, 2014; 289 (34): 23428-36.


Up-regulation of Kir2.1 (KCNJ2) by the serum & glucocorticoid inducible SGK3., Munoz C., Cell Physiol Biochem. January 1, 2014; 33 (2): 491-500.


Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel., Park MH., J Pharmacol Sci. September 20, 2013; 123 (1): 67-77.


Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells., Jehle J., Br J Pharmacol. March 1, 2013; 168 (5): 1215-29.


Blocking of the human ether-à-go-go-related gene channel by imatinib mesylate., Dong Q., Biol Pharm Bull. January 1, 2013; 36 (2): 268-75.


hERG K+ channel-associated cardiac effects of the antidepressant drug desipramine., Staudacher I., Naunyn Schmiedebergs Arch Pharmacol. February 1, 2011; 383 (2): 119-39.


Response of i(kr) and HERG currents to the antipsychotics tiapride and sulpiride., Jo SH., Korean J Physiol Pharmacol. October 1, 2010; 14 (5): 305-10.


Differential expression of hERG1 channel isoforms reproduces properties of native I(Kr) and modulates cardiac action potential characteristics., Larsen AP., PLoS One. February 2, 2010; 5 (2): e9021.            


Selective noradrenaline reuptake inhibitor atomoxetine directly blocks hERG currents., Scherer D., Br J Pharmacol. January 1, 2009; 156 (2): 226-36.


Papaverine, a vasodilator, blocks the pore of the HERG channel at submicromolar concentration., Kim YJ., J Cardiovasc Pharmacol. December 1, 2008; 52 (6): 485-93.


Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current., Larsen AP., Pflugers Arch. September 1, 2008; 456 (6): 1137-48.


Molecular interaction of droperidol with human ether-a-go-go-related gene channels: prolongation of action potential duration without inducing early afterdepolarization., Schwoerer AP., Anesthesiology. May 1, 2007; 106 (5): 967-76.


Biophysical characterization of the new human ether-a-go-go-related gene channel opener NS3623 [N-(4-bromo-2-(1H-tetrazol-5-yl)-phenyl)-N'-(3'-trifluoromethylphenyl)urea]., Hansen RS., Mol Pharmacol. October 1, 2006; 70 (4): 1319-29.


Blockade of HERG human K+ channel and IKr of guinea pig cardiomyocytes by prochlorperazine., Kim MD., Eur J Pharmacol. August 21, 2006; 544 (1-3): 82-90.


Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine., Lee SY., Br J Pharmacol. June 1, 2006; 148 (4): 499-509.


Frequency-dependent modulation of KCNQ1 and HERG1 potassium channels., Diness TG., Biochem Biophys Res Commun. May 19, 2006; 343 (4): 1224-33.


Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643)., Hansen RS., Mol Pharmacol. January 1, 2006; 69 (1): 266-77.


Inhibition of human ether-a-go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine., Choi SY., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.


Class Ia anti-arrhythmic drug ajmaline blocks HERG potassium channels: mode of action., Kiesecker C., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 423-35.


Direct block of hERG potassium channels by the protein kinase C inhibitor bisindolylmaleimide I (GF109203X)., Thomas D., Cardiovasc Res. December 1, 2004; 64 (3): 467-76.


Activation properties of Kv4.3 channels: time, voltage and [K+]o dependence., Wang S., J Physiol. June 15, 2004; 557 (Pt 3): 705-17.


Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin., Thomas D., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2004; 369 (5): 462-72.


Block of HERG human K(+) channel and IKr of guinea pig cardiomyocytes by chlorpromazine., Lee SY., J Cardiovasc Pharmacol. May 1, 2004; 43 (5): 706-14.


Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine., Scholz EP., Naunyn Schmiedebergs Arch Pharmacol. November 1, 2003; 368 (5): 404-14.


Inhibitory effect of the class III antiarrhythmic drug nifekalant on HERG channels: mode of action., Kushida S., Eur J Pharmacol. December 13, 2002; 457 (1): 19-27.


Interaction with GM130 during HERG ion channel trafficking. Disruption by type 2 congenital long QT syndrome mutations. Human Ether-à-go-go-Related Gene., Roti EC., J Biol Chem. December 6, 2002; 277 (49): 47779-85.


[Evaluation of pro-arrhythmic risk of drugs due to QT interval prolongation by the HERG expression system]., Chachin M., Nihon Yakurigaku Zasshi. June 1, 2002; 119 (6): 345-51.


Inhibition of cardiac potassium currents by pentobarbital., Bachmann A., Naunyn Schmiedebergs Arch Pharmacol. January 1, 2002; 365 (1): 29-37.


Characterization of a novel Kv1.5 channel blocker in Xenopus oocytes, CHO cells, human and rat cardiomyocytes., Bachmann A., Naunyn Schmiedebergs Arch Pharmacol. November 1, 2001; 364 (5): 472-8.


High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872., Thomas D., J Pharmacol Exp Ther. May 1, 2001; 297 (2): 753-61.


Blocking effects of the antiarrhythmic drug propafenone on the HERG potassium channel., Mergenthaler J., Naunyn Schmiedebergs Arch Pharmacol. April 1, 2001; 363 (4): 472-80.


Inhibitory effects of berberine on IK1, IK, and HERG channels of cardiac myocytes., Li BX., Acta Pharmacol Sin. February 1, 2001; 22 (2): 125-31.


Inhibition of IKs channels by HMR 1556., Gögelein H., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2000; 362 (6): 480-8.


KChAP as a chaperone for specific K(+) channels., Kuryshev YA., Am J Physiol Cell Physiol. May 1, 2000; 278 (5): C931-41.


Norpropoxyphene-induced cardiotoxicity is associated with changes in ion-selectivity and gating of HERG currents., Ulens C., Cardiovasc Res. December 1, 1999; 44 (3): 568-78.


Mechanism for the effects of extracellular acidification on HERG-channel function., Jiang M., Am J Physiol. October 1, 1999; 277 (4): H1283-92.


Pathways of HERG inactivation., Kiehn J., Am J Physiol. July 1, 1999; 277 (1): H199-210.


HERG potassium channel activation is shifted by phorbol esters via protein kinase A-dependent pathways., Kiehn J., J Biol Chem. September 25, 1998; 273 (39): 25285-91.


Effects of the chromanol 293B, a selective blocker of the slow, component of the delayed rectifier K+ current, on repolarization in human and guinea pig ventricular myocytes., Bosch RF., Cardiovasc Res. May 1, 1998; 38 (2): 441-50.


Blockade of HERG channels by the class III antiarrhythmic azimilide: mode of action., Busch AE., Br J Pharmacol. January 1, 1998; 123 (1): 23-30.


Suppression of slow delayed rectifier current by a truncated isoform of KvLQT1 cloned from normal human heart., Jiang M., J Biol Chem. September 26, 1997; 272 (39): 24109-12.


A minK-HERG complex regulates the cardiac potassium current I(Kr)., McDonald TV., Nature. July 17, 1997; 388 (6639): 289-92.


Suppression of mammalian K+ channel family by ebastine., Ko CM., J Pharmacol Exp Ther. April 1, 1997; 281 (1): 233-44.


Single HERG delayed rectifier K+ channels expressed in Xenopus oocytes., Zou A., Am J Physiol. March 1, 1997; 272 (3 Pt 2): H1309-14.

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