Papers associated with head (and gabarap)

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	GABAergic Neurotransmission in Human Tissues Is Modulated by Cannabidiol., Ruffolo G., Life (Basel). December 6, 2022; 12 (12):
	GABAA receptor function is enhanced by Interleukin-10 in human epileptogenic gangliogliomas and its effect is counteracted by Interleukin-1β., Ruffolo G., Sci Rep. October 26, 2022; 12 (1): 17956.
	Unexpected Effect of IL-1β on the Function of GABAA Receptors in Pediatric Focal Cortical Dysplasia., Alfano V., Brain Sci. June 19, 2022; 12 (6):
	Basmisanil, a highly selective GABAA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man., Hipp JF., Sci Rep. April 8, 2021; 11 (1): 7700.
	GABAA Receptors Expressed in Oligodendrocytes Cultured from the Neonatal Rat Contain α3 and γ1 Subunits and Present Differential Functional and Pharmacological Properties., Ordaz RP., Mol Pharmacol. February 1, 2021; 99 (2): 133-146.
	GABAA Receptor Subunit Composition Drives Its Sensitivity to the Insecticide Fipronil., Soualah Z., Front Neurosci. January 1, 2021; 15 768466.
	In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders., Grupe M., Eur J Pharmacol. November 15, 2020; 887 173440.
	The desensitization pathway of GABAA receptors, one subunit at a time., Gielen M., Nat Commun. October 23, 2020; 11 (1): 5369.
	Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites., Germann AL., Mol Pharmacol. October 1, 2020; 98 (4): 280-291.
	Erythropoietin Increases GABAA Currents in Human Cortex from TLE Patients., Roseti C., Neuroscience. July 15, 2020; 439 153-162.
	Differential Coassembly of α1-GABAARs Associated with Epileptic Encephalopathy., Hannan S., J Neurosci. July 15, 2020; 40 (29): 5518-5530.
	Cloning and Expression of Cockroach α7 Nicotinic Acetylcholine Receptor Subunit., Cartereau A., Front Physiol. January 1, 2020; 11 418.
	Steady-state activation of the high-affinity isoform of the α4β2δ GABAA receptor., Pierce SR., Sci Rep. November 5, 2019; 9 (1): 15997.
	Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions., Anderson LL., Epilepsia. November 1, 2019; 60 (11): 2224-2234.
	Involvement of the GABAA receptor α subunit in the mode of action of etifoxine., Mattei C., Pharmacol Res. July 1, 2019; 145 104250.
	Multiple actions of fenamates and other nonsteroidal anti-inflammatory drugs on GABAA receptors., Mansikkamäki S., Eur J Pharmacol. June 15, 2019; 853 247-255.
	Ketone body modulation of ligand-gated ion channels., Pflanz NC., Neuropharmacology. April 1, 2019; 148 21-30.
	Design and Synthesis of Novel Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors with the Ability To Rescue Auditory Gating Deficit in Mice., Li Y., J Med Chem. January 10, 2019; 62 (1): 159-173.
	A novel GABAergic dysfunction in human Dravet syndrome., Ruffolo G., Epilepsia. November 1, 2018; 59 (11): 2106-2117.
	Suramin is a novel competitive antagonist selective to α1β2γ2 GABAA over ρ1 GABAC receptors., Luo H., Neuropharmacology. October 1, 2018; 141 148-157.
	Structural basis of neurosteroid anesthetic action on GABAA receptors., Chen Q., Nat Commun. September 28, 2018; 9 (1): 3972.
	Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission., Knoflach F., J Vis Exp. August 16, 2018; (138):
	A novel action of lacosamide on GABAA currents sets the ground for a synergic interaction with levetiracetam in treatment of epilepsy., Ruffolo G., Neurobiol Dis. July 1, 2018; 115 59-68.
	Direct intertectal inputs are an integral component of the bilateral sensorimotor circuit for behavior in Xenopus tadpoles., Gambrill AC., J Neurophysiol. May 1, 2018; 119 (5): 1947-1961.
	Assembly rules for GABAA receptor complexes in the brain., Martenson JS., Elife. August 17, 2017; 6
	Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes., Borghese CM., Sci Rep. July 24, 2017; 7 (1): 6230.
	HPLC-Based Activity Profiling for GABAA Receptor Modulators in Extracts: Validation of an Approach Utilizing a Larval Zebrafish Locomotor Assay., Moradi-Afrapoli F., J Nat Prod. May 26, 2017; 80 (5): 1548-1557.
	GABAB receptor attenuation of GABAA currents in neurons of the mammalian central nervous system., Shen W., Physiol Rep. March 1, 2017; 5 (6):
	Preclinical development of moxidectin as a novel therapeutic for alcohol use disorder., Huynh N., Neuropharmacology. February 1, 2017; 113 (Pt A): 60-70.
	Low Expression in Xenopus Oocytes and Unusual Functional Properties of α1β2γ2 GABAA Receptors with Non-Conventional Subunit Arrangement., Baur R., PLoS One. January 3, 2017; 12 (1): e0170572.
	Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the α5 subunit., Stamenić TT., Eur J Pharmacol. November 15, 2016; 791 433-443.
	Functional aspects of early brain development are preserved in tuberous sclerosis complex (TSC) epileptogenic lesions., Ruffolo G., Neurobiol Dis. November 1, 2016; 95 93-101.
	Cannabis in epilepsy: From clinical practice to basic research focusing on the possible role of cannabidivarin., Morano A., Epilepsia Open. September 19, 2016; 1 (3-4): 145-151.
	Molecular mode of action of CGS 9895 at α1 β2 γ2 GABAA receptors., Maldifassi MC., J Neurochem. September 1, 2016; 138 (5): 722-30.
	A pharmacological assessment of agonists and modulators at α4β2γ2 and α4β2δ GABAA receptors: The challenge in comparing apples with oranges., Ahring PK., Pharmacol Res. September 1, 2016; 111 563-576.
	Zolpidem is a potent stoichiometry-selective modulator of α1β3 GABAA receptors: evidence of a novel benzodiazepine site in the α1-α1 interface., Che Has AT., Sci Rep. June 27, 2016; 6 28674.
	Functional sites involved in modulation of the GABAA receptor channel by the intravenous anesthetics propofol, etomidate and pentobarbital., Maldifassi MC., Neuropharmacology. June 1, 2016; 105 207-214.
	Novel positive allosteric modulators of GABAA receptors with anesthetic activity., Maldifassi MC., Sci Rep. May 20, 2016; 6 25943.
	Pharmacological induction of skin pigmentation unveils the neuroendocrine circuit regulated by light., Bertolesi GE., Pigment Cell Melanoma Res. March 1, 2016; 29 (2): 186-98.
	A Cysteine Substitution Probes β3H267 Interactions with Propofol and Other Potent Anesthetics in α1β3γ2L γ-Aminobutyric Acid Type A Receptors., Stern AT., Anesthesiology. January 1, 2016; 124 (1): 89-100.
	Structure-dependent inhibition of the human α1β2γ2 GABAA receptor by piperazine derivatives: A novel mode of action., Hondebrink L., Neurotoxicology. December 1, 2015; 51 1-9.
	A novel GABA(A) alpha 5 receptor inhibitor with therapeutic potential., Ling I., Eur J Pharmacol. October 5, 2015; 764 497-507.
	GABAA currents are decreased by IL-1β in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis., Roseti C., Neurobiol Dis. October 1, 2015; 82 311-320.
	Direct evidence for GABAergic activity of Withania somnifera on mammalian ionotropic GABAA and GABAρ receptors., Candelario M., J Ethnopharmacol. August 2, 2015; 171 264-72.
	Positive modulation of synaptic and extrasynaptic GABAA receptors by an antagonist of the high affinity benzodiazepine binding site., Middendorp SJ., Neuropharmacology. August 1, 2015; 95 459-67.
	A Multifaceted GABAA Receptor Modulator: Functional Properties and Mechanism of Action of the Sedative-Hypnotic and Recreational Drug Methaqualone (Quaalude)., Hammer H., Mol Pharmacol. August 1, 2015; 88 (2): 401-20.
	Re-engineering a neuroprotective, clinical drug as a procognitive agent with high in vivo potency and with GABAA potentiating activity for use in dementia., Luo J., BMC Neurosci. June 19, 2015; 16 67.
	MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity., Rosso JP., Proc Natl Acad Sci U S A. February 24, 2015; 112 (8): E891-900.
	Inhibitory effects of insulin on GABAA currents modulated by the GABAA alpha subunit., Williams DB., J Recept Signal Transduct Res. January 1, 2015; 35 (6): 516-22.
	Probing α4βδ GABAA receptor heterogeneity: differential regional effects of a functionally selective α4β1δ/α4β3δ receptor agonist on tonic and phasic inhibition in rat brain., Hoestgaard-Jensen K., J Neurosci. December 3, 2014; 34 (49): 16256-72.

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